161 research outputs found
Raising Self-Awareness and Developing Intercultural Competence by Activating Personal Filters
All individuals are fitted with filters which affect their experience of the world, and which depend on various factors, including personal traits and cultural influences. Language is a reflection of the self, and of the culture and people it belongs to, thus when learning a new language each individual is approaching a different identity and culture with personal filters which act on the learning process. Learning involves approaching something new and inevitably leads to some change, which may occur without conscious awareness but is affected by the individual’s attitude towards novelty and diversity.This joint project involved learners of English (Parma University) and of Italian (University of Salzburg) as L2, and aimed at indirectly testing these filters. The objectives were to verify if their filters are subtly expressed in their way of seeing themselves, their own language and culture, and the ‘other’ language and culture, and also raise their awareness of them. This hopefully is a stepping stone towards discovering aspects of their personality, developing sensitivity to differences and recognizing factors to be exploited to become more efficient learners
Positioning tips for distal fibula ankle fracture fixation
Patient positioning is key to successful fixation of distal fibula fractures. When supine, the leg rests in an externally rotated or neutral position. The leg must be rotated internally throughout the operation to enable adequate visualisation of the lateral ankle. Exposure is improved by elevating the ipsilateral hip with a sandbag. However, in patients with a stiff hip or excessive external rotation, this is not enough. In these cases, exposure can be improved further by placing a size 7.5 or greater glove over the foot and securing the glove fingers over the contralateral foot. This provides internal rotation throughout the operation and covers dirty toes
An Example of the Use of Interdigital PVDF Transducers to Generate and Receive a High Order Lamb Wave Mode in a Pipe
From a non-destructive evaluation point of view, Lamb waves are a highly attractive means of inspecting a large area of a structure from a single point. Interdigital PVDF transducers have been used previously in signal processing applications [1] to generate acoustic waves in piezoelectric substrates. This paper in conjunction with that of Monkhouse et al [2] aims to provide an overview of the work accomplished so far at Imperial College in the use of interdigital PVDF transducers to transmit and receive Lamb waves in certain structures for non-destructive evaluation purposes. Interdigital PVDF transducers may be permanently bonded to either flat of curved surfaces and this attribute together with their low cost means that they are potentially suitable for“smart structure” applications
DF-4 defibrillator downgrade to pacemaker, a novel method of device downgrade for implantable cardioverter-defibrillator patients
Exploiting SMART pass filter deactivation detection to minimize inappropriate subcutaneous implantable cardioverter defibrillator therapies: a real-world single-centre experience and management guide
Laser-In-Situ Monitoring of Combustion Processes
Several examples of laser in situ monitoring of combustion processes are presented. Using a frequency modulated 13CO2 waveguide laser, in situ concentrations of NH3 down to 1 ppm were measured at temperatures up to 600°C in waste incinerators and power or chemical plants. Following ignition of CH3OH-O2 mixtures by a TEA CO2 laser, gas temperature profiles were measured using rapid scanning tunable diode laser spectroscopy of CO molecules. In laminar CH4-air counterflow diffusion flames at atmospheric pressure absolute concentrations, temperatures, and collisional lifetimes of OH radicals were determined by 2-D and picosecond LIF and absorption spectroscopy. Two-dimensional LIF and Mie scattering were used to observe fuel injection and combustion in a diesel engine.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/86767/1/Sick52.pd
Temperature and Pressure Dependences of the Laser-Induced Fluorescence of Gas-Phase Acetone and 3-Pentanone
Laser-Induced Fluorescence (LIF) from the S1 state of acetone and 3-pentanone was studied as a function of temperature and pressure using excitation at 248 nm. Additionally, LIF of 3-pentanone was investigated using 277 and 312 nm excitation. Added gases were synthetic air, O2, and N2 respectively, in the range 0–50 bar. At 383 K and for excitation at 248 nm, all the chosen collision partners gave an initial enhancement in fluorescence intensity with added gas pressure. Thereafter, the signal intensity remained constant for N2 but decreased markedly for O2. For synthetic air, only a small decrease occurred beyond 25 bar. At longer excitation wavelengths (277 and 312 nm), the corresponding initial rise in signal with synthetic air pressure was less than that for 248 nm. The temperature dependence of the fluorescence intensity was determined in the range 383–640 K at a constant pressure of 1 bar synthetic air. For 248 nm excitation, a marked fall in the fluorescence signal was observed, whereas for 277 nm excitation the corresponding decrease was only half as strong. By contrast, exciting 3-pentanone at 312 nm, the signal intensity increased markedly in the same temperature range. These results are consistent with the observation of a red shift of the absorption spectra (9 nm) over this temperature range. Essentially, the same temperature dependence was obtained at 10 and 20 bar pressure of synthetic air. It is demonstrated that temperatures can be determined from the relative fluorescence intensities following excitation of 3-pentanone at 248 and 312 nm, respectively. This new approach could be of interest as a non-intrusive thermometry method, e.g., for the compression phase in combustion engines.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/86780/1/Sick44.pd
Razvoj matriksnih sustava za transdermalnu isporuku pentazocina: In vitro/in vivo ispitivanje
The present study aimed to develop hydroxypropyl methylcellulose based transdermal delivery of pentazocine. In formulations containing lower proportions of polymer, the drug released followed the Higuchi kinetics while, with an increase in polymer content, it followed the zero-order release kinetics. Release exponent (n) values imply that the release of pentazocine from matrices was non-Fickian. FT-IR, DSC and XRD studies indicated no interaction between drug and polymer.
The in vitro dissolution rate constant, dissolution half-life and pharmacokinetic parameters (Cmax, tmax, AUC(s), t1/2, Kel, and MRT) were evaluated statistically by two-way ANOVA. A significant difference was observed between but not within the tested products. Statistically, a good correlation was found between per cent of drug absorbed from patches vs. Cmax, and AUC(s). A good correlation was also observed when per cent drug released was correlated with the blood drug concentration obtained at the same time point. The results of this study indicate that the polymeric matrix films of pentazocine hold potential for transdermal drug delivery.U radu je opisan razvoj transdermalnih sustava na bazi hidroksipropil metilceluloze za isporuku pentazocina. U pripravcima koji sadrže manje udjele polimera, otpuštanje lijeka slijedilo je Higuchijevu kinetiku. Međutim, ako je udio polimera veći oslobađanje je najbolje odgovaralo kinetici nultog reda. Vrijednost eksponenta n implicira da oslobađanje pentazocina iz matriksa nije po Fickovom zakonu. FT-IR, DSC i X RD studije ukazuju da nema interakcije između ljekovite tvari i polimera.
In vitro konstanta oslobađanja, poluvrijeme oslobađanja i farmakokinetički parametri (Cmax, tmax, AUC(s), t1/2, Kel, i MRT) procijenjeni su statistički koristeći ANOVA program. Značajna razlika primijećena je između, ali ne i unutar testiranih pripravaka. Pronađena je dobra korelacija između lijeka apsorbiranog iz flastera i Cmax i AUC(s) te oslobođenog lijeka i koncentracije lijeka u krvi. Rezultati ukazuju da su polimerni matriksni filmovi pentazocina potencijalno dobri sustavi za transdermalnu primjenu lijeka
A nurse-led implantable loop recorder service is safe and cost effective
Introduction: Implantable loop recorders (ILR) are predominantly implanted by cardiologists in the catheter laboratory. We developed a nurse‐delivered service for the implantation of LINQ (Medtronic; Minnesota) ILRs in the outpatient setting. This study compared the safety and cost‐effectiveness of the introduction of this nurse‐delivered ILR service with contemporaneous physician‐led procedures. /
Methods: Consecutive patients undergoing an ILR at our institution between 1st July 2016 and 4th June 2018 were included. Data were prospectively entered into a computerized database, which was retrospectively analyzed. /
Results: A total of 475 patients underwent ILR implantation, 271 (57%) of these were implanted by physicians in the catheter laboratory and 204 (43%) by nurses in the outpatient setting. Six complications occurred in physician‐implants and two in nurse‐implants (P = .3). Procedural time for physician‐implants (13.4 ± 8.0 minutes) and nurse‐implants (14.2 ± 10.1 minutes) were comparable (P = .98). The procedural cost was estimated as £576.02 for physician‐implants against £279.95 with nurse‐implants, equating to a 57.3% cost reduction. In our center, the total cost of ILR implantation in the catheter laboratory by physicians was £10 513.13 p.a. vs £6661.55 p.a. with a nurse‐delivered model. When overheads for running, cleaning, and maintaining were accounted for, we estimated a saving of £68 685.75 was performed by moving to a nurse‐delivered model for ILR implants. Over 133 catheter laboratory and implanting physician hours were saved and utilized for other more complex procedures. /
Conclusion: ILR implantation in the outpatient setting by suitably trained nurses is safe and leads to significant financial savings
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