Systolic blood pressure in quintiles of protein intake, stratified by hypertension status.

<p>SBP = systolic blood pressure. p_interaction for total protein = 0.14, p_interaction for animal protein = 0.16, p_interaction for plant protein = <0.01. Values are average BP and 95% confidence interval, adjusted for age, gender, BMI, education, smoking, alcohol consumption, total energy, saturated fatty acids, carbohydrates, fiber, calcium, magnesium, potassium, and protein intake from other sources than the one under study, if applicable.</p

Characteristics by quintiles of energy adjusted total protein intake of 20,820 Dutch adults.

<p>Unless indicated otherwise, data are presented as mean ± SD or %.</p>1<p>Hypertension is defined as systolic BP≥140 mmHg or diastolic BP≥90 mmHg (participants using antihypertensive medication were excluded).</p>2<p>Data from a subgroup (n = 16,073). In consecutive quintiles n = 3,255, n = 3,229, n = 3,190, n = 3,184, and n = 3,215. High physical activity was defined as ≥3.5 hours moderate activity (4.0>MET≥6.5) and ≥2 h/wk vigorous activity (MET≥6.5).</p>3<p>Percentage of alcohol consumers in consecutive quintiles 63%, 63%, 63%, 60% and 58%.</p>4<p>Presented as median with interquartile range because of skewed distribution.</p>5<p>Protein intake from all kind of milk, yogurt, coffee creamer, curd, pudding, porridge, custard, whipped cream, and cheese.</p>6<p>Protein intake from all kind of meats, meat products and poultry.</p>7<p>Plant protein intake from all kinds of breads, cake and cookies, grains and grain products.</p

Fully adjusted systolic and diastolic BP levels in 20,820 untreated Dutch adults in quintiles of energy adjusted total, animal and plant protein intake.

<p>Values are average BP and 95% confidence interval.</p><p>Model 1: Adjusted for age and gender.</p><p>Model 2: Additionally adjusted for BMI, educational level, smoking, and alcohol consumption.</p><p>Model 3: Additionally adjusted for total energy, saturated fatty acids, carbohydrates, fiber, calcium, magnesium, potassium, and protein intake from other sources than the one under study, if applicable.</p

Distribution of patients over the risk groups for all patients (n = 1892) and BCG treated patients (n = 449).

<p>*The high risk group is the combined group from intermediate-high and high-risk EORTC and CUETO scores, because of low patient numbers.</p

A–F. Kaplan-Meier estimates of recurrence of bladder cancer in a ten-year period from transurethral resection of a non-muscle invasive bladder tumour.

<p>Full line: low risk patients, dotted line: intermediate risk patients, dashed line: high risk patients. Number of patients per country: Denmark n = 280; The Netherlands n = 639; Spain n = 973.</p

A–F. Kaplan-Meier estimates of progression of bladder cancer in a ten-year period from transurethral resection of a non-muscle invasive bladder tumour.

<p>Full line: low risk patients, dotted line: intermediate risk patients, dashed line: high risk patients. Number of patients per country: Denmark n = 280; The Netherlands n = 639; Spain n = 973.</p