International Competitive Strategy Choices: Comparing Firms in China and India

The international business literature has yet to adequately explore international competitive strategy choices made by firms in developing countries. This study aims to address this gap by investigating the types of international competitive strategies followed by Chinese and Indian firms. Using firm-level primary data, the study analyzes factors that affect strategy choices and whether these factors differ between the two countries. The empirical results indicate that besides cost leadership strategies, firms have already developed international differentiation strategies and strategies combining cost and differentiation advantages (hybrid strategies). This confirms that firms from China and India are moving to international markets not only because of their low cost advantage but also because they are upgrading their capabilities to compete in the global market. The study highlights the fact that firms’ resources and capabilities influence firms’ propensity to choose a specific international competitive strategy and that the strategies can also differ in relation to the destination market. In general, the pursuit of well-articulated international competitive strategies (in particular differentiation strategy) is more common among Indian firms than among Chinese firms.

Cost of health care utilization among homeless frequent emergency department users

Research demonstrates that homelessness is associated with frequent use of emergency department (ED) services, yet prior studies have not adequately examined the relationship between frequent ED use and utilization of non-ED health care services among those experiencing homelessness. There has also been little effort to assess heterogeneity among homeless individuals who make frequent use of ED services. To address these gaps, the present study used Medicaid claims data from 2010 to estimate the association between the number of ED visits and non-ED health care costs for a cohort of 6,338 Boston Health Care for the Homeless Program patients, and to identify distinct subgroups of persons in this cohort who made frequent use of ED services based on their clinical and demographic characteristics. A series of gamma regression models found more frequent ED use to be associated with higher non-ED costs, even after adjusting for demographic and clinical characteristics. Latent class analysis was used to examine heterogeneity among frequent ED users, and the results identified 6 characteristically distinct subgroups among these persons. The subgroup of persons with trimorbid illness had non-ED costs that far exceeded members of all 5 other subgroups. Study findings reinforce the connection between frequent ED use and high health care costs among homeless individuals and suggest that different groups of homeless frequent ED users may benefit from interventions that vary in terms of their composition and intensity

Asian American College Students and Civic Engagement

This chapter centers Asian American young adults within a discussion about civic engagement by highlighting findings from 35 years of data on Asian American college freshmen. It will also address future directions for Asian American undergraduate student civic engagement, taking immigration and population trends into account. Calling attention to Asian American civic engagement within the college context achieves at least two main goals. First, it will help scholars, practitioners, and policy makers move beyond racial stereotypes of this group and consider their complete college experiences, including their involvement outside the classroom. Doing so will help facilitate efforts to develop curricular and co-curricular practices that can better serve the learning and development of this fast-growing population in higher education. Second, examining these patterns of civic engagement will shed light on how Asian American students, as part of the future of our nation, are positioned for greater participation in a democratic U.S. society

Searching on the go : the effects of fragmented attention on mobile web search tasks

Smart phones and tablets are rapidly becoming our main method of accessing information and are frequently used to perform on-the-go search tasks. Mobile devices are commonly used in situations where attention must be divided, such as when walking down a street. Research suggests that this increases cognitive load and, therefore, may have an impact on performance. In this work we conducted a laboratory experiment with both device types in which we simulated everyday, common mobile situations that may cause fragmented attention, impact search performance and affect user perception. Our results showed that the fragmented attention induced by the simulated conditions significantly affected both participants' objective and perceived search performance, as well as how hurried they felt and how engaged they were in the tasks. Furthermore, the type of device used also impacted how users felt about the search tasks, how well they performed and the amount of time they spent engaged in the tasks. These novel insights provide useful information to inform the design of future interfaces for mobile search and give us a greater understanding of how context and device size affect search behaviour and user experience

The 11 March 2011 Tohoku tsunami wavefront mapping across offshore Southern California

The 11 March 2011 (M_w = 9.0) Tohoku tsunami was recorded by a temporary array of seafloor pressure gauges deployed off the coast of Southern California, demonstrating how dense array data can illustrate and empirically validate predictions of linear tsunami wave propagation characteristics. A noise cross-correlation method was used to first correct for the pressure gauge instrument phase response. Phase and group travel times were then measured for the first arrival in the pressure gauge tsunami waveforms filtered in narrow bands around 30 periods between 200 and 3000 s. For each period, phase velocities were estimated across the pressure gauge array based on the phase travel time gradient using eikonal tomography. Clear correlation was observed between the phase velocity and long-wavelength bathymetry variations where fast and slow velocities occurred for deep and shallow water regions, respectively. In particular, velocity gradients are pronounced at the Patton Escarpment and near island plateaus due to the abrupt bathymetry change. In the deep open ocean area, clear phase velocity dispersion is observed. Comparison with numerically calculated tsunami waveforms validates the approach and provides an independent measure of the finite-frequency effect on phase velocities at long periods

Singular limits for the bi-laplacian operator with exponential nonlinearity in R4\R^4

Let $\Omega$ be a bounded smooth domain in $\mathbb{R}^{4}$ such that for some integer $d\geq1$ its $d$-th singular cohomology group with coefficients in some field is not zero, then problem {\Delta^{2}u-\rho^{4}k(x)e^{u}=0 & \hbox{in}\Omega, u=\Delta u=0 & \hbox{on}\partial\Omega, has a solution blowing-up, as $\rho\to0$, at $m$ points of $\Omega$, for any given number $m$.Comment: 30 pages, to appear in Ann. IHP Non Linear Analysi

Epitopes Targeted by Bullous Pemphigoid T Lymphocytes and Autoantibodies Map to the Same Sites on the Bullous Pemphigoid 180 Ectodomain

Bullous pemphigoid is a blistering skin disease characterized by autoantibodies directed against the NC16A domain of bullous pemphigoid 180 (collagen XVII), a transmembrane protein of epidermal basal cells. Passive transfer studies in mice have shown that antibodies that bind to this immunodominant region of bullous pemphigoid 180 are capable of inducing a skin disease that closely mimics bullous pemphigoid, supporting the hypothesis that epitopes within NC16A are involved in the pathogenesis of bullous pemphigoid. In this study, we examined the autoimmune T cell response in bullous pemphigoid patients. T cells from eight of 12 bullous pemphigoid patients, all of whom had circulating anti-bullous pemphigoid 180 autoantibodies, showed a specific proliferative response to recombinant forms of NC16A. T cell lines and clones developed from four of these patients recognize the same NC16A peptides as those targeted by autoantibodies from the corresponding individuals. These NC16A-responding T lymphocytes express alpha/beta T cell receptors and CD4 memory T cell surface markers and exhibited a Th1/Th2 mixed cytokine profile that may support the production of antibodies. This new information will aid in defining the key steps involved in the development of the autoimmune response in bullous pemphigoid

Chemical composition and cytotoxic properties of Clinacanthus nutans root extracts

Context: Clinacanthus nutans Lindau (Acanthaceae) is a medicinal plant that has been reported to have anti-inflammatory, antiviral, antimicrobial and antivenom activities. In Malaysia, it has been widely claimed to be effective in various cancer treatments but scientific evidence is lacking. Objective: This study investigates the chemical constituents, anti-proliferative, and apoptotic properties of C. nutans root extracts. Materials and methods: The roots were subjected to solvent extraction using methanol and ethyl acetate. The anti-proliferative effects of root extracts were tested at the concentrations of 10 to 50 μg/mL on MCF-7 and HeLa by using 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay for 72 h. Morphological changes were observed under light microscope. Pro-apoptotic effects of root extracts were examined using flow cytometric analysis and RT-PCR. The chemical compositions of root extracts were detected using GC-MS. Results: The proliferation of MCF-7 cells was inhibited with the IC50 values of 35 and 30 μg/mL, respectively, for methanol and ethyl acetate root extracts. The average inhibition of HeLa cells was ∼25%. Induction of apoptosis in MCF-7 was supported by chromatin condensation, down-regulation of BCL2 and unaltered expression of BAX. However, only ethyl acetate extract caused the loss of mitochondrial membrane potential. GC-MS analysis revealed the roots extracts were rich with terpenoids and phytosterols. Discussion and conclusions: The results demonstrated that root extracts promote apoptosis by suppressing BCL2 via mitochondria-dependent or independent manner. The identified compounds might work solely or cooperatively in regulating apoptosis. However, further studies are required to address this