Gambaran Kadar Kreatinin Serum Pada Pasien Penyakit Ginjal Kronik Stadium 5 Non Dialisis

: Chronic kidney disease is a pathophysiology process with various etiology, causing a progressive decline on kidney function, and in general ends with kidney failure (stage 5). For the last forty years, creatinine serum had been the most common and affordable detection serum to measure kidney performance. The amount of creatinine serum is increased on non-dialysis chronic kidney disease patients. Approximately, 57% of non-dialysis chronic kidney disease patients have 7-12 mg/dL creatinine level. Research objective: To understand the description of creatinine serum level on non-dialysis chronic kidney disease patients. Research method: Cross sectional descriptive, to obtain the data of creatinine serum on non-dialysis chronic kidney disease patients carried out on December 2015 – January 2016 at two hospitals, which are RSUP. Prof. Dr. R. D. Kandou Manado and Rumah Sakit Advent Manado. The research sample were the blood sample from 35 people suffering a stage five non dialysis chronic kidney disease, which determined by consecutive sampling from non-probability sampling model. Result: Based on the laboratory result, the 35 patients diagnosed with a stage five non dialysis chronic kidney disease are undergoing an increase on creatinine serum (100%). Conclusion: Based on the research result, it can be concluded that the increase of creatinine level is occurred on stage five non dialysis chronic kidney disease patients

Hitung Jenis Leukosit Pada Pasien Anak Dengan Infeksi Virus Dengue Di Manado

: Dengue is the most rapidly spreading mosquito-borne viral disease in the world. The decreasing leukocytes can be found between the third and eighth day with normal differential telling. The number of granulocytes decreases on the third until the eighth day. This study used a cross-sectional design. esearch. Samples were children with dengue virus infection at Wolter Mongisidi Hospital, Advent Hospital, and Pancaran Kasih Hospital in Manado from December 2014 until January 2015. There were 36 children as samples. The results showed that 48.6% of samples had increases of basophils, 54% had decreases of eosinophils, 64.8% had decreases of neutrophils, 54% had increases of lymphocytes, and 59.4% had increases of monocytes. Conclusion: In this study, most of the children with dengue viral infection had decreased number of neutrophil

Gambaran Kadar Serum Magnesium Pada Pasien Penyakit Ginjal Kronik Stadium 5 Non Dialisis Di Manado

: Magnesium is a metal, one of the eight most abundant element in universe. Magnesium also is a mineral that responsible for bone metabolism control, neural transmission, cardiac excitability, neuromuscular conduction, muscular contraction, vasomotor, and blood pressure. In chronic kidney disease stage 4-5, compensation mechanism become inadequate that caused a hypermagnesemia. Objectives: This study aimed to know the picture of magnesium serum in non dialysis CKD stage 5 in Manado. Material Methods: This is a descriptive study, conducted by selecting 35 blood samples in Nephrology-Hypertension Polyclinic and IRINA of Interna of Prof. Dr. R.D Kandou Hospital and Teling Adventist Hospital. Result: There are 16 samples (45.7%) experience hypomagnesemia consisted of 8 home-care patient (22.9%) and 8 hospital-care patient (22.9%), 10 samples (28.6%) are in normal range consisted of 3 home-care patient (8.6%) and 7 hospital-care patient (20.0%), and 9 samples (25.7%) are experience hypermagnesemia consisted of 6 home-care patient (17.1%) and 3 hospital-care patient (8.6%) from total non dialysis CKD stage 5 samples result from laboratory examination. Conclusion: Patient with hypomagnesemia most frekuent than patient with hypermagnesemia

Gambaran Kadar Kalium Serum Pada Pasien Penyakit Ginjal Kronik Stadium 5 Non Dialisis Di Manado

: Potassium is the main intracellular ion in the body and plays a key role in maintaining cell function. Total body potassium distributed 98% in intracellular and 2% in extracellular fluid. A slight change in the distribution of these can cause hypokalemia or hyperkalemia. A healthy kidney has great capacity to maintain potassium homeostasis in the cace of excess potassium. The kidney is primarily responsible for maintaining total body potassium content by matching potassium intake with potassium excretion. This study aimed to obtain the profile of potassium serum in non dialysis CKD stage 5 patients in Manado. This was an obsevartional descriptive study. There were 35 blood samples obtained from patients in Nephrology-Hypertension Polyclinic and IRINA of Prof. Dr. R.D Kandou Hospital and Teling Adventist Hospital. There were 11 samples (31,4%) with hypokalemia consisted of 6 home-care patients (35.3%) and 5 hospital-care patients (27.8%), 15 samples (42.9%) were in normal range consisted of 8 home-care patients (47.1%) and 7 hospital-care patients (38.9%), and 9 samples (25.7%) with hyperkalemia consisted of 3 home-care patients (17.6%) and 6 hospital-care patients (33,3%) from total non-dialysis CKD stage 5 samples resulted from laboratory examination. Conclusion: In non dialysis CKD stage 5 patients in Manado, normokalemia was the most common found than hypokalemia and hyperkalemia

Perbandingan Nilai Agregasi Trombosit Pada Pasien Hipertensi Yang Diberi Aspirin Dan Tidak Diberi Aspirin Di Rsup. Prof. Dr. R. D. Kandou Manado

: Thrombocyte hyperaggregation occurs in hypertensive patients. Thrombocyte accumulates and thrombi formation caused by hyperaggregation are important factors in pathogenesis of cardiovaskular and cerebrovascular disease. Around 50 million people consume aspirin everyday to treat or to prevent cardiovascular or cerebrovascular disease. The use of aspirin known can increase bleeding risk especially when trauma occurs or intraoperative, but inhypertensive patients50 or over 50 years old, the benefit of aspirin can be greater then the bleeding risk it carries. Method: This study used comparative study, which compared thrombocyte aggregation value in hypertensive patients with aspirin and without aspirin. The tools that used for thrombocyte aggregation examination is an aggregometer and the data analysis is done by using SPSS software. Result: The difference value of thrombocyte aggregation in hypertensive patients with aspirin and without aspirin used T 2 independent samples test gave significant for ADP 10 µM and 5 µM(p <0.05), respectively 0.001 and 0.01. Conclusion: There is a difference between thrombocyte aggregation value in hypertensive patients with aspirin and without aspirin. Mean value ofthrombocyte aggregation in hypertensive patients with aspirin is lower than hypertensive patients without aspirin

Gambaran Berat Jenis Urin Pada Pasien Tuberkulosis Paru Dewasa Di Rsup Prof. Dr. R. D. Kandou Manado

: Tuberculosis (TB) is a chronic infectious disease caused by Mycobacterium Tuberculosis. Drugs that given to the TB patients such as isoniazid, pyrazinamide, ethambutol, streptomycin, and rifampicin. Rifampicin and streptomycin can damage the kidneys and can changes in the urine specific gravity. This study aims to describe the specific gravity of urine in adult pulmonary TB patients in the department of Prof. Dr. R. D. Kandou Manado. This research uses descriptive observational method by means of random consecutive sampling to obtain data on the weight of the urine in adult pulmonary TB patients conducted in October-November 2016 in the department Prof. Dr. R. D. Kandou Manado. The sample used is a urine sample from pulmonary TB patient with inclusion criteria. The result of urine specific gravity test that obtained from 30 patients with pulmonary tuberculosis, 27 patients (90%) with the results of 1010-1025, 1 patient (3.33%) with the results of the urine specific gravity ≤1.005, and 2 patients with the results of the urine specific gravity ≥ 1030. outpatients have an average urine specific gravity higher than inpatients. Overview urine specific gravity in this study largely still in the normal range