Polarimetric detection of laser induced ultrashort magnetic pulses in overdense plasma

The interaction of intense ( ~ 1016 Wcm-2), subpicosecond pulses with solid targets can generate highly directional jets of hot electrons. These electrons can propagate in the solid along with the counterpropagating return shielding currents. The spontaneous magnetic field that is generated by these currents, captures in its time evolution, important information about the dynamics of the complex transport processes. By using a two pulse pump-probe polarimetric technique the temporal evolution of multimegagauss magnetic fields is measured for optically polished BK7 glass targets, each coated with a thin layer of either copper or silver. A simple model is then used for explaining the observations and for deducing quantitative information about the transport of hot electrons

The beneficial role of N-acetylcysteine as an adjunctive drug in treatment of COVID-19 patients in a tertiary care hospital in India: an observational study

Background: N-acetyl cysteine, a mucolytic agent, demonstrates free radical scavenging and anti-inflammatory properties, and prevents endothelial dysfunction by inhibition of NF-KB and formation of no adducts. This has a potential role to tackle cytokine storms, endothelial dysfunction and prothrombotic state observed in COVID-19 manifestations like ARDS and Multi organ dysfunction.Methods: Institution based descriptive cross sectional study, 164 patients from laboratory confirmed RT PCR positive COVID-19 patients, in the study period from 27th May 2020 to 10th August 2020, were assessed, in medical college Kolkata, a dedicated COVID-19 care facility.Results: It was observed that moderate-severe patients who received N-acetyl cysteine along with standard therapy had average hospital stay duration of 12 days, higher rate of discharge, average duration of oxygen therapy of 8 days, less number of deaths and reduced transfer to critical care facilities.Conclusions: N-acetyl cysteine can be considered as an adjunctive therapy with standard protocol driven care, due to its beneficial anti-inflammatory and free radical scavenging properties

Effect of substitution at amine functionality of 2,6-Diaminopyridine-coupled rhodamine on metal-ion interaction and self-assembly

2,6-Diaminopyridine-coupled rhodamines 1 and 2 have been synthesized, and the effect of substitution on amine functionality toward metal-ion interactions and self-assembly is thoroughly investigated. Both the compounds effectively recognize different metal ions of biological significance fluorimetrically and colorimetrically with a high degree of selectivity and sensitivities. While compound 1 is sensitive to Fe3+ ions, compound 2 is responsive to both Fe3+ and Al3+ ions in aqueous CH3CN (4/1, v/v; 10 mM tris HCl buffer, pH 6.8). The sensing mechanism involves the metal-ion chelation-induced spirolactam ring opening of the rhodamine scaffold that results in both color and fluorescence changes, while the extent of interactions with the metal ions is truly governed by the chemical structure of the compounds. Both 1 and 2 are proficient in detecting Fe3+ and Al3+ ions in human lung cancer cells (A549). As new findings, unlike 1, compound 2 formed a faint pink gel in the toluene-hexane mixture solvent (1:1, v/v), and the gel state of 2 selectively recognizes Ag+ ions by exhibiting a phase change from gel to purple sol. Experimental findings establish the role of the formamide moiety in forming the self-assembly

Measurements of high energy density electrons via observation of Cherenkov radiation

Copyright 2010 American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The following article appeared in Physics of Plasmas, 17(5), 056306, 2010 and may be found at http://dx.doi.org/10.1063/1.334637

Direct, absolute, and in situ measurement of fast electron transport via cherenkov emission

We present direct measurements of the absolute energy distribution of relativistic electrons generated in intense, femtosecond laser interaction with a solid. Cherenkov emission radiated by these electrons in a novel prism target is spectrally dispersed to obtain yield and energy distribution of electrons simultaneously. A crucial advance is the observation of high density electron current as predicted by particle simulations and its transport as it happens inside the target. In addition, the strong sheath potential present at the rear side of the target is inferred from a comparison of the electron spectra derived from Cherenkov light observation with that from a magnet spectrometer

Constraining R-parity violating couplings using dimuon data at Tevatron Run-II

The dimuon plus dijet signal is analyzed in the top squark pair production at Tevatron Run-II experiment and the total event rate is compared with the existing dimuon data. This comparison rules out top squark mass upto 188(104) GeV for the branching fraction 100%(50%) of top squark decay into the muon plus quark via lepton number violating coupling. Interpretation of this limit in the framework of R-parity violating(RPV) SUSY model puts limit on relevant RPV coupling for a given top squark mass and other supersymmetric model parameters. If \MST \lsim 180 GeV we found that the RPV couplings are roughly restricted to be within $\sim 10^{-4}$ which is at the same ballpark value obtained from the neutrino data. The limits are very stringent for a scenario where top squarks appear to be the next lightest supersymmetric particles.Comment: 7 pages, 3 figures,added minor clarifications,version to appear in Phys. Lett.

Constraining top squark in R-parity violating SUSY model using existing Tevatron data

Signal of lighter top squark has been looked for using Tevatron data in the di-electron plus di-jet channel. We find that the mass of the lighter top squark when it decays dominantly in the electron plus jet channel, can be ruled out up to 220 GeV at 95% C.L. using di-electron data. In the framework of R-parity breaking SUSY model we exclude relevant R-parity violating couplings for a range of top squark masses and other SUSY parameters. The bounds on R-parity violating couplings are very stringent for the parameter space where lighter top squark turns out to be the next to lightest supersymmetric particle.Comment: 12 pages, 4 Figures, LateX, minor changes, few references added, version to appear in Physical Rev.

Application of Matched-Filter Concepts to Unbiased Selection of Data in Pump-Probe Experiments with Free Electron Lasers

Pump-probe experiments are commonly used at Free Electron Lasers (FEL) to elucidate the femtosecond dynamics of atoms, molecules, clusters, liquids and solids. Maximizing the signal-to-noise ratio of the measurements is often a primary need of the experiment, and the aggregation of repeated, rapid, scans of the pump-probe delay is preferable to a single long-lasting scan. The limited availability of beamtime makes it impractical to repeat measurements indiscriminately, and the large, rapid flow of single-shot data that need to be processed and aggregated into a dataset, makes it difficult to assess the quality of a measurement in real time. In post-analysis it is then necessary to devise unbiased criteria to select or reject datasets, and to assign the weight with which they enter the analysis. One such case was the measurement of the lifetime of Intermolecular Coulombic Decay in the weakly-bound neon dimer. We report on the method we used to accomplish this goal for the pump-probe delay scans that constitute the core of the measurement; namely we report on the use of simple auto- and cross-correlation techniques based on the general concept of “matched filter”. We are able to unambiguously assess the signal-to-noise ratio (SNR) of each scan, which then becomes the weight with which a scan enters the average of multiple scans. We also observe a clear gap in the values of SNR, and we discard all the scans below a SNR of 0.45. We are able to generate an average delay scan profile, suitable for further analysis: in our previous work we used it for comparison with theory. Here we argue that the method is sufficiently simple and devoid of human action to be applicable not only in post-analysis, but also for the real-time assessment of the quality of a dataset