Comparison of 7T 16-channel Dual-row Transmit Arrays

We evaluated and compared the performance of an inductively decoupled and overlapped dual-row transmit arrays for MRI at 7T. For the evaluated designs, the coupling between adjacent elements in the same row was higher for the overlapped compared to the non-overlapped configuration. However the transmit efficiencies for the circular polarization mode of both coils were similar. For comparisons of array transmit performance, consideration of array-internal losses as well as reflected and radiated power is very important, because their sum can be as high as 55% of the total transmit power

DNA repair phenotype and dietary antioxidant supplementation

Phytochemicals may protect cellular DNA by direct antioxidant effect or modulation of the DNA repair activity. We investigated the repair activity towards oxidised DNA in human mononuclear blood cells (MNBC) in two placebo-controlled antioxidant intervention studies as follows: (1) wellnourished subjects who ingested 600 g fruits and vegetables, or tablets containing the equivalent amount of vitamins and minerals, for 24 d; (2) poorly nourished male smokers who ingested 500 mg vitamin C/d as slow- or plain-release formulations together with 182 mg vitamin E/d for 4 weeks. The mean baseline levels of DNA repair incisions were 65\u20222 (95% CI 60\u20224, 70\u20220) and 86\u20221 (95% CI 76\u20222, 99\u20229) among the male smokers and well-nourished subjects, respectively. The male smokers also had high baseline levels of oxidised guanines in MNBC. After supplementation, only the male smokers supplemented with slow-release vitamin C tablets had increased DNA repair activity (27 (95% CI 12, 41) % higher incision activity). These subjects also benefited from the supplementation by reduced levels of oxidised guanines in MNBC. In conclusion, nutritional status, DNA repair activity and DNA damage are linked, and beneficial effects of antioxidants might only be observed among poorly nourished subjects with high levels of oxidised DNA damage and low repair activity

Assessment of collateral supply by two-coil continuous arterial spin labeling after coil occlusion of the internal carotid artery.

A patient undergoing coil occlusion of a left internal carotid artery aneurysm was investigated by continuous arterial spin labeling MR imaging to evaluate perfusion territory mapping. Labeling was restricted to the left- or right-sided carotid artery by use of a separate neck coil. Before embolization, perfusion contrast was largely restricted to the labeled hemisphere. After embolization, perfusion contrast was created symmetrically in both hemispheres on labeling the right side, verifying sufficient collateral supply