Sequences of weak solutions for fractional equations

This work is devoted to study the existence of infinitely many weak solutions to nonlocal equations involving a general integrodifferential operator of fractional type. These equations have a variational structure and we find a sequence of nontrivial weak solutions for them exploiting the ${\mathbb{Z}}_2$-symmetric version of the Mountain Pass Theorem. To make the nonlinear methods work, some careful analysis of the fractional spaces involved is necessary. As a particular case, we derive an existence theorem for the fractional Laplacian, finding nontrivial solutions of the equation \left\{\begin{array}{ll} (-\Delta)^s u=f(x,u) & {\mbox{in}} \Omega\\ u=0 & {\mbox{in}} \erre^n\setminus \Omega. \end{array} \right. As far as we know, all these results are new and represent a fractional version of classical theorems obtained working with Laplacian equations

Yamabe-type equations on Carnot groups

This article is concerned with a class of elliptic equations on Carnot groups depending of one real positive parameter and involving a critical nonlinearity. As a special case of our results we prove the existence of at least one nontrivial solution for a subelliptic critical equation defined on a smooth and bounded domain $D$ of the {Heisenberg group} $\mathbb{H}^n=\mathbb{C}^n\times \mathbb{R}$. Our approach is based on pure variational methods and locally sequentially weakly lower semicontinuous arguments

Existence Results for a critical fractional equation

We are concerned with existence results for a critical problem of Brezis-Nirenberg Type involving an integro-differential operator. Our study includes the fractional Laplacian. Our approach still applies when adding small singular terms. It hinges on appropriate choices of parameters in the mountain-pass theore

Existence results for nonlinear elliptic problems on fractal domains

Some existence results for a parametric Dirichlet problem defined on the Sierpi\'nski fractal are proved. More precisely, a critical point result for differentiable functionals is exploited in order to prove the existence of a well determined open interval of positive eigenvalues for which the problem admits at least one non-trivial weak solution

Nonlinear equations involving the square root of the Laplacian

In this paper we discuss the existence and non-existence of weak solutions to parametric fractional equations involving the square root of the Laplacian $A_{1/2}$ in a smooth bounded domain $\Omega\subset \mathbb{R}^n$ ($n\geq 2$) and with zero Dirichlet boundary conditions. Namely, our simple model is the following equation \begin{equation*} \left\{ \begin{array}{ll} A_{1/2}u=\lambda f(u) & \mbox{ in } \Omega\\ u=0 & \mbox{ on } \partial\Omega. \end{array}\right. \end{equation*} The existence of at least two non-trivial $L^{\infty}$-bounded weak solutions is established for large value of the parameter $\lambda$ requiring that the nonlinear term $f$ is continuous, superlinear at zero and sublinear at infinity. Our approach is based on variational arguments and a suitable variant of the Caffarelli-Silvestre extension method

Multiple solutions of nonlinear equations involving the square root of the Laplacian

In this paper we examine the existence of multiple solutions of parametric fractional equations involving the square root of the Laplacian $A_{1/2}$ in a smooth bounded domain $\Omega\subset \mathbb{R}^n$ ($n\geq 2$) and with Dirichlet zero-boundary conditions, i.e. \begin{equation*} \left\{ \begin{array}{ll} A_{1/2}u=\lambda f(u) & \mbox{ in } \Omega\\ u=0 & \mbox{ on } \partial\Omega. \end{array}\right. \end{equation*} The existence of at least three $L^{\infty}$-bounded weak solutions is established for certain values of the parameter $\lambda$ requiring that the nonlinear term $f$ is continuous and with a suitable growth. Our approach is based on variational arguments and a variant of Caffarelli-Silvestre's extension method

Multiplicity results for elliptic Kirchhoff-type problems

Abstract The aim of this paper is to establish the existence of multiple solutions for a perturbed Kirchhoff-type problem depending on two real parameters. More precisely, we show that an appropriate oscillating behaviour of the nonlinear part, even under small perturbations, ensures the existence of at least three nontrivial weak solutions. Our approach combines variational methods with properties of nonlocal fractional operators

Clinical relevance and treatment of nonautoimmune anemia in chronic lymphocytic leukemia

Anemia has an unfavorable impact on quality of life in chronic lymphocytic leukemia (CLL), increases the likelihood of receiving blood transfusions, and eventually has a negative impact on overall survival. Although discrepancies in perception of health-related quality of life between doctors and patients lead to the undertreatment of anemia, CLL patients undergoing chemotherapy who have a hemoglobin level <10 g/dL should be considered for treatment with erythropoiesis-stimulating agents. For hemoglobin values of 10–12 g/dL, the role of performance status and comorbidities should not be underestimated. In this setting, the evaluation of physical fitness using the Cumulative Illness Rating Scale should help physicians to identify those patients with hemoglobin levels of 10–12 g/dL who are suitable for therapy with erythropoiesis-stimulating agents. Finally, the increasing use of aggressive approaches to therapy should encourage physicians towards appropriate management of chemotherapy-induced anemia in CLL patients