Percutaneous lipiodol lymphangiogram in chylous leakage successful embolisation post mastectomy: a case report

Complication of chyle leakage is rare post mastectomy, ranging from 0.36 – 0.84%. This case report discuses a rare case of chylous leakage post mastectomy in a 79-year-old female. The complication was suspected when the draining colour of axillary drainage change from serous fluid to milky colour, diagnosis then confirmed clinically and biochemically as chyle. The patient was initially managed conservatively, but this was not successful and was referred to an interventional radiology for lymphangiogram and embolization. Percutaneous lipiodol embolization was performed with immediate success

Successful intravenous thrombolysis of a wake-up stroke with underlying valvular atrial fibrillation

A 42-year-old female admitted with new-onset atrial fibrillation had a wake-up stroke on the high-dependency unit and the time last seen well (TLSW) was 6.5 h. She suffered left-sided body weakness and her National Institutes of Health Stroke Scale (NIHSS) score was 17. An emergency CT perfusion showed right M1 segment occlusion with more than 50% penumbra. She was given recombinant tissue plasminogen activator (r-tPA) at 9 h from TLSW. An immediate diagnostic angiogram with intention to treat, owing to the presence of large vessel occlusion, showed complete reperfusion after intravenous r-tPA. She was discharged with NIHSS of 2, and at 3-month follow up her Modified Rankin Scale was 0. We demonstrated a successful reperfusion and excellent clinical recovery with intravenous thrombolysis in a patient who presented with a wake-up stroke with underlying valvular atrial fibrillation despite evidence of large vessel occlusion. © 2018, Royal College of Physicians of Edinburgh. All rights reserved

Giant intracavernous aneurysm presenting with isolated trigeminal neuralgia: a case report

Background: Trigeminal neuralgia (TN) commonly affects individuals aged more than 50 years and is mostly primary owing to trigeminal nerve neurovascular compression. We report a case of secondary TN attributed to a giant intracavernous aneurysm compressing the trigeminal nerve. Case presentation: A 74-year-old female presented with classic TN symptoms, which were initially refractory to medical treatment. Imaging including MRI brain, MR angiography, and cerebral angiogram revealed a giant intracavernous aneurysm measuring 1.7 cm × 2.8 cm, inducing mass effect on the left Meckel's cave. Aneurysm embolization was challenging due to the difficult cannulation of the distal portion of the aneurysm. The patient opted for conservative management with mild improvement of symptoms. Conclusions: Intracavernous aneurysm rarely present with isolated trigeminal neuralgia. This case report emphasizes that the assessment of the intracranial vasculature should be considered as part of the diagnostic imaging work-up for patients presenting with TN

A complete right oculomotor nerve palsy secondary to carotid cavernous fistula with a background of poorly controlled diabetes: a case report

Background: The coulometer or the third cranial nerve gives innervation to the four of the six extraocular muscles, namely the medial rectus, superior rectus, inferior rectus, inferior oblique. This cranial nerve is responsible for the upward and downward as well as adduction movement of the eyeball. It also retract the upper eyelid by innervating the levator palpebrae superioris muscle.Oculomotor nerve regulates the pupillary constriction via the parasympathetic nervous system. Oculomotor nerve palsy may affect any of these roles depending from its aetiology. Case presentation: We are reporting a case of complete right sided oculomotor nerve palsy secondary to carotid cavernous fistulain a poorly controlled diabetic patient. This patient had a complete right sided ptosis with the eyeball deviated to the ‘down and out’ position in keeping with dilated pupil. A magnetic resonance angiography had confirmed the diagnosis of carotidcavernous fistula of which an urgent embolization procedure was performed. Conclusions: Diagnosing an oculomotor cranial nerve palsy correctly and to determine its exact etiology is vital. A complete, pupil-involving oculomotor nerve palsy warrants an urgent radiological imaging as to accurately localized the lesion that give rise to the presenting symptoms

Pre-operative spine embolisation for spinal tumors and metastases: 6 years experience at Pusat Perubatan Universiti Kebangsaan Malaysia

Objective: Our aim is to determine the average intraoperative blood loss in patients who underwent pre-operative spinal tumour embolisation in PPUKM from 2010 until 2016 and to compare with other centres from literature review. Material And Methodology: 15 patients in PPUKM with spinal tumour and spinal metastatic disease underwent pre-operative embolisation before palliative spinal surgery between 2010 and 2016 in PPUKM. Intraoperative blood loss during palliative spinal surgery was documented obtaining the average and median blood loss. Secondary analyses were made on the amount of intraoperative blood loss in comparison to the embolisation materials, degree of embolisation completion, primary malignancy, level of spinal metastatic involvement and total operating time. Result: The average and median intraoperative blood loss during palliative spinal surgery were 1480mls and 1000mls respectively, which is comparable with other centre from literature review. Significant difference is noted in intraoperative blood loss between the different embolisation materials used (P<0.01). 10 patients had complete embolisation and 4 patients had incomplete embolisation with significant difference in terms of blood loss between these 2 groups with P value of <0.01. There was significant positive correlation between operating time and intra-operative blood loss, whereby the longer the operation, the higher the amount of blood loss. Conclusion: The average intraoperative blood loss in patients with pre-operative spinal tumour embolisation in PPUKM is comparable to other centres from literature review thus pre-operative tumour embolisation can reduce perioperative haemorrhage. However, larger study is needed to further analyse correlation between these factors in affecting intraoperative blood loss

Spontaneous thrombosis of non-tuberculous pulmonary artery mycotic pseudoaneurysm in prolonged childhood pneumonia

Pulmonary tuberculosis (PTB) is common in tropical country like Malaysia. Prolonged PTB infection may lead to mycotic pulmonary artery pseudoaneurysm (PAP). We report a case of childhood non-tuberculous pulmonary infection causing mycotic PAP which resolved spontaneously after antibiotics therapy. A 1 year 6 months old girl underlying Down syndrome presented with prolonged fever for two weeks , cough and breathlessness. Her leucocytes count were elevated and she developed several hypotensive episodes secondary to septicaemia. Chest radiograph showed loculated right sided pleural effusion. Ultrasound revealed complex pleural collection and initial aspiration revealed a thick stale blood. Thinking of possible vascular cause, ultrasound able to locate a well-defined rounded structure with high flow velocity seen on Doppler ultrasound consistent with pseudoaneurysm and CT thorax confirmed the findings. Pulmonary artery angiogram prior to embolization revealed no evidence of abnormal vasculature or contrast blush at the region of interest. Complimentary ultrasound showed evidence of spontaneous thrombosis within the pseudoaneurysm. Non-tuberculous PAP is a rare but possible life-threatening sequela of pneumonia. Pleural drainage in a haemothorax with concomitant mycotic thoracic pseudoaneurysm may cause loss of pressure tamponade and will end up with devastating consequences. Careful ultrasound image acquisition must be made by the attending radiologist prior to pleural drainage

The prominent hypointense vessel sign on susceptibility-weighted imaging (SWI) as a potential imaging biomarker for poor clinical outcome in acute ischemic stroke (AIS)

Susceptibility-weighted imaging (SWI) is a relatively new magnetic resonance imaging (MRI) technique used in the workup and diagnosis of brain pathologies. In the context of acute ischemic stroke (AIS), it is increasingly becoming useful in the diagnosis, treatment, and further management of these patients. An elderly man with metabolic syndrome presented to us with an acute onset of right sided body weakness and aphasia. Urgent imaging via MRI noted a left middle cerebral artery (MCA) occlusion. Diffusion-weighted imaging (DWI)/fluid attenuated inversion recovery (FLAIR) mismatch was noted with an acute infarct involving the left MCA territory; hence, treatment with intravenous (IV) thrombolysis was administered. On SWI, the prominent hypointense vessel sign was noted. Recanalization of the occluded left MCA was seen on diagnostic cerebral angiography post IV thrombolysis, however, the patient was noted to have early neurological deterioration (END) and poor early stage clinical outcome, despite repeat MRI showing recanalization of the left MCA occlusion and reversal of the prominent hypointense vessel sign on SWI. Presence of the prominent hypointense vessel sign on SWI in AIS patients is associated with poor clinical outcome, unsuccessful recanalization rates, END, poor early stage clinical outcome, and infarct core progression. Some studies have shown an association between this imaging sign and poor collateral circulation status. Therefore, this imaging sign could potentially prove to be a useful imaging biomarker. However, more studies are needed to validate this theory

Spontaneous Middle Cerebral Artery (MCA) dissection and stenosis: Role of vessel wall imaging and 3D-RA endoluminal view as adjunct diagnostic tools in endovascular therapy

Intracranial dissection has a wide spectrum of clinical presentation from causing intracranial hemorrhage to steno-occlusive ischemia. Anterior intracranial circulation is an uncommon site for dissection. Multimodality imaging is required before deciding on the best treatment for each patient. We present a case of left middle cerebral artery dissection causing steno-occlusive ischemia and hypoperfusion. This case demonstrates how MRI vessel wall imaging and endoluminal view of three-dimensional rotational angiogram as an adjunct tool to help us diagnosed and achieve optimum endovascular therapy for our patients

Spontaneous Middle Cerebral Artery MCA dissection and stenosis: role of vessel wall imaging and 3D-RA endoluminal view as adjunct diagnostic tools in endovascular therapy

Intracranial dissection has a wide spectrum of clinical presentation from causing intracranial hemorrhage to steno-occlusive ischemia. Anterior intracranial circulation is an uncommon site for dissection. Multimodality imaging is required before deciding on the best treatment for each patient. We present a case of left middle cerebral artery dissection causing steno-occlusive ischemia and hypoperfusion. This case demonstrates how MRI vessel wall imaging and endoluminal view of three-dimensional rotational angiogram as an adjunct tool to help us diagnosed and achieve optimum endovascular therapy for our patients

False negative bronchial artery caliber on multi-detector computed tomography in predicting outcome of bronchial artery embolization in patient with haemoptysis

Bronchial artery embolization was first performed in 1973 by Remy et al with widespread acceptance since then. Multi-detector computed tomography (MDCT) CT angiography (CTA) is currently the gold standard imaging modality used to identify the site and cause of bleeding in patient presented with haemoptysis. Bronchial artery anatomies and precise location can be obtained by scrutinizing CTA prior to interventional procedures. CTA has the advantage of not only can preclude the need of digital subtraction angiography (DSA) in inappropriate cases, but also can shorten the intervention procedure timing. We present a case of false negative bronchial artery caliber seen on MDCT which was abnormal in DSA