Improving Voltage Profile of Islanded Microgrid using PI Controller

In islanding operating mode of microgrid, the voltage and frequency of system must be maintained by the microgrid, or else the system will crumble due to the characteristics of different distributed generators (DG) utilized in microgrid. The voltage and frequency lost provision when main grid is disconnected. This paper presents PI controller based voltage controller to regulate voltage to its normal condition. The controller is proposed to be utilized individually with each distributed generator (DG) in microgrid. The controller compares inverter output voltage with voltage at point of common coupling (PCC) and its output is feed to PWM pulse generator to generate appropriate pulses for inverter to regulate voltage to its nominal value. The simulation results of proposed system are shown using MATLAB/Simulink platform

A Review paper based on spectrum sensing techniques in Cognitive Radio Networks

Natural frequency spectrum is scared resource; the efficient use of it can only accommodate the need of future computing world. But efficient use of it is not possible within the existing system, where the allocation of spectrum is done based on fixed spectrum access (FSA) policy. Many survey shows that it leads to under use of spectrum. For efficient utilization of spectrum innovative techniques is needed. using Dynamic spectrum access (DSA) policy we can exploiting the available spectrum, For given purpose Cognitive radio arises to be a tempting solution to the spectral congestion problem by introducing opportunistic usage of the frequency bands that are not heavily occupied by licensed users. This paper presents the study of different spectrum sensing techniques of cognitive radio networks. As we know Cognitive radio is a form of wireless communication where radio transceiver intelligently detects which spectrums are free which are not. After this it occupies the vacant one while avoiding busy one spectrum. Cognitive radios promote open spectrum allocation which is a clear departure from traditional command and control allocation schemes for radio spectrum usage. In short, they allow the formation of “infrastructure-less” collaborative network clusters—cognitive radio networks. However, how to detect free spectrum we have to use the spectrum sensing techniques, here we are describing all the spectrum sensing techniques and Finally concluded that cooperative sensing is better than Non-Cooperative sensing for primary user (PU) signal with  low SNR value. Keywords- CRN, FSA, PU, DSA, SU, SNR.

Accelerated Design of Chalcogenide Glasses through Interpretable Machine Learning for Composition Property Relationships

Chalcogenide glasses possess several outstanding properties that enable several ground breaking applications, such as optical discs, infrared cameras, and thermal imaging systems. Despite the ubiquitous usage of these glasses, the composition property relationships in these materials remain poorly understood. Here, we use a large experimental dataset comprising approx 24000 glass compositions made of 51 distinct elements from the periodic table to develop machine learning models for predicting 12 properties, namely, annealing point, bulk modulus, density, Vickers hardness, Littleton point, Youngs modulus, shear modulus, softening point, thermal expansion coefficient, glass transition temperature, liquidus temperature, and refractive index. These models, by far, are the largest for chalcogenide glasses. Further, we use SHAP, a game theory based algorithm, to interpret the output of machine learning algorithms by analyzing the contributions of each element towards the models prediction of a property. This provides a powerful tool for experimentalists to interpret the models prediction and hence design new glass compositions with targeted properties. Finally, using the models, we develop several glass selection charts that can potentially aid in the rational design of novel chalcogenide glasses for various applications.Comment: 17 pages, 8 figure

THERAPIES OVER MEDICATION: COMPARING THE EFFECT OF TENS AND CUPPING THERAPY TO ENHANCE THE PERFORMANCE IN FEMALE COLLEGE GOING STUDENTS

Introduction: Education is about teaching, learning skills and knowledge. And if we talk about college and universities, they have different kind of furniture which is not fit for all students few and very short and very long for that so, everyone cannot fit in same. The leading technologies lead to impact on student’s posture and posture impairment causes impact on the back and that result in pain. And pain causes, impact on performance. That pain and their effects on student’s performance related to back activity. Performance is the completion of a task with application of knowledge, skills and abilities. Methodology: Study was observational; a total number of sixty samples was selected from Noida and G. Noida. Simple random sampling was used, upon evaluation the inclusion criteria were (1). Female students (2).Age: 18to 25yrs (3). BMI: 19.5 - 24.9 kg/m2. (4) Sitting duration 4hrs/day (5). Chronic back pain for three months. Exclusion criteria were (1). Low and high BP (2). Any pathological condition. (3). Neurological deficits (4). Menstrual irregularities. After that, all subjects were randomly assigned to one of the four groups. Group 1 has given the Tens and Group 2 has given the Cupping therapy. Both the groups have further divided according to the treatment duration 5min and 10min. Treatment description: Tens and Cupping were performed for all the groups the electrodes and cups were placed over the area of most severe pain. The treatment was administered for the specific duration of each group. Result & Conclusion: In our study, we have found that the cupping therapy is equally effective as compared to Tens when the treatment were given for 5min Tens comes out more effective and Cupping is more effective when the therapy time duration is 10min. So, Cupping therapy can be used as an alternative method of back pain therapy depends upon the situation.  Article visualizations

Comparative Molecular Docking Studies with ABCC1 and Aquaporin 9 in the Arsenite Complex Efflux

Arsenic is the most toxic metalloid present in the natural environment in both organic and inorganic arsenic forms. Inorganic arsenic is often more hazardous than the organic form. Arsenite and arsenate compounds are the major inorganic forms which are toxic causing severe human health dysfunction including cancer. Excretion of arsenic from the system is found elusive. Therefore, it is of interest to screen channel proteins with the arsenic complex in the different combination of arsenic, GSH (glutathione) and arsenic, selenium using docking methods. The mode of arsenic removal. The complex structure revealed the mode of arsenic binding efficiency with the receptor aquaporine 9 and ABCC1 channel protein. This provides insights to understand the mechanism of arsenic efflux. These inferences find application in the design, identification and development of novel nutracetucal or any other formulation useful in the balance of arsenic efflux

THERAPIES OVER MEDICATION: COMPARING THE EFFECT OF TENS AND CUPPING THERAPY TO ENHANCE THE PERFORMANCE IN FEMALE COLLEGE GOING STUDENTS

Introduction: Education is about teaching, learning skills and knowledge. And if we talk about college and universities, they have different kind of furniture which is not fit for all students few and very short and very long for that so, everyone cannot fit in same. The leading technologies lead to impact on student’s posture and posture impairment causes impact on the back and that result in pain. And pain causes, impact on performance. That pain and their effects on student’s performance related to back activity. Performance is the completion of a task with application of knowledge, skills and abilities. Methodology: Study was observational; a total number of sixty samples was selected from Noida and G. Noida. Simple random sampling was used, upon evaluation the inclusion criteria were (1). Female students (2).Age: 18to 25yrs (3). BMI: 19.5 - 24.9 kg/m2. (4) Sitting duration 4hrs/day (5). Chronic back pain for three months. Exclusion criteria were (1). Low and high BP (2). Any pathological condition. (3). Neurological deficits (4). Menstrual irregularities. After that, all subjects were randomly assigned to one of the four groups. Group 1 has given the Tens and Group 2 has given the Cupping therapy. Both the groups have further divided according to the treatment duration 5min and 10min. Treatment description: Tens and Cupping were performed for all the groups the electrodes and cups were placed over the area of most severe pain. The treatment was administered for the specific duration of each group. Result & Conclusion: In our study, we have found that the cupping therapy is equally effective as compared to Tens when the treatment were given for 5min Tens comes out more effective and Cupping is more effective when the therapy time duration is 10min. So, Cupping therapy can be used as an alternative method of back pain therapy depends upon the situation

Correlation of circulatory VEGF and miRNA 126 in angiographically proven coronary artery disease and its clinical importance

Background: Atherosclerotic ischemic coronary artery disease (CAD) is a major cause of morbidity and mortality in both developed and developing countries, indicating the need for the discovery of deeper molecular insights of CAD mechanisms, biomarkers, and innovative therapeutic targets. Vascular endothelial growth factor (VEGF) may have some role, in the progression of human coronary atherosclerosis. Circulating microRNAs (miR) have a potential as a diagnostic as well as a prognostic biomarker of cardiovascular disease and dysfunctions. Aims and Objectives: The aim of the study was to correlate the levels of miRNA-126 and VEGF in the serum of CAD patients. Materials and Methods: The study was conducted on 100 cases of freshly diagnosed CAD patients (angiographically proven) and 80 normal healthy patients. Various serum biomarkers were estimated. The level of serum VEGF and Mi-RNA was correlated for CAD patients. Results: Highly significantly difference was found in levels of hemoglobin A1C, low density lipoprotein, total cholesterol, and total homocysteine while high-density lipoproteins and triglycerides were less significantly different for controls and cases. VEGF levels of CAD cases were found to be very significantly higher as compared to controls. The miRNA-126 expression was found to be lower in the CAD subjects compared to non-CAD subjects. Conclusion: The study was suggested the role of VEGF in atherogenesis and plaque instability. No significant correlation was found among between miR-126 levels and VEGF levels among CAD cases. The study is limited by a smaller sample size and was single-centered; therefore, multicentric study with a larger patient cohort needs to be done and to validate our findings

Analysis of adverse drug reactions of antimicrobial agents reported to ADR monitoring centre of a rural tertiary care teaching hospital

Background: ADRs are iatrogenic diseases, escalates the burden of health care system by increasing the morbidity and mortality and also additional cost of ADRs management to patients.Methods: A prospective observational study was conducted over 1 year from January 2015 to December 2015. The yellow forms dropped in the red ADR boxes are collected and ADRs due to antimicrobials were analyzed for demographic data, causality, severity, drugs implicated, and organ system affected. The data were presented as counts and percentages.Results: Cephalosporins were the most common antimicrobial class implicated in ADRs, and the dermatological system was the most common system affected by ADRs. All the reactions either belonged to the probable or possible category. Majority of reactions were non-serious.Conclusions: Regular prescription auditing and awareness about polypharmacy will further reduce ADRs due to antimicrobials

Molecular Docking of Known Carcinogen 4- (Methyl-nitrosamino)-1-(3-pyridyl)-1-butanone (NNK) with Cyclin Dependent Kinases towards Its Potential Role in Cell Cycle Perturbation

Cell cycle is maintained almost all the times and is controlled by various regulatory proteins and their complexes (Cdk+Cyclin) in different phases of interphase (G1, S and G2) and mitosis of cell cycle. A number of mechanisms have been proposed for the initiation and progression of carcinogenesis by abruption in cell cycle process. One of the important features of cancer/carcinogenesis is functional loss of these cell cycle regulatory proteins particularly in CDKs and cyclins. We hypothesize that there is a direct involvement of these cell cycle regulatory proteins not only at the genetic level but also proteins level, during the initiation of carcinogenesis. Therefore, it becomes significant to determine inconsistency in the functioning of regulatory proteins due to interaction with carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Hence, we investigated the interaction efficiency of NNK, against cell cycle regulatory proteins. We found a different value of ΔG (free energy of binding) among the studied proteins ranging between -3.29 to -7.25 kcal/mol was observed. To validate the results, we considered Human Oxy-Hemoglobin at 1.25 Å Resolution, [PDB_ID:1HHO] as a +ve control, (binding energy -6.06 kcal/mol). Finally, the CDK8 (PDB_ID:3RGF) and CDK2 (PDB_ID:3DDP) regulatory proteins showing significantly strong molecular interaction with NNK -7.25 kcal/mol, -6.19 kcal/mol respectively were analyzed in details. In this study we predicted that CDK8 protein fails to form functional complex with its complementary partner cyclin C in presence of NNK. Consequently, inconsistency of functioning in regulatory proteins might lead to the abruption in cell cycle progression; contribute to the loss of cell cycle control and subsequently increasing the possibility of carcinogenesis