The Reading Perception Of Medical Staff About The Use Of Prehospital Ultrasound

This study was a focus on the use of pre-hospital ultrasound in Saudi Arabia. Generally, ultrasound is used in a high frequency by health care providers in different countries within hospitals or pre-hospital. The main point of using the ultrasound was to reduce the time of diagnosis at the hospital and decrease the rate of mortality and morbidity. The study was a cross-sectional study and was used to assess the perception of medical staff about the use of pre-hospital ultrasound. This survey study had 130 participants, and 80 of them were agreed to involve in this study. It was conducted in King Abdulaziz Hospital of National Guards, Al Ahsa and College of Applied Medical Sciences, King Saud Bin Abdul Aziz University for Health Sciences, Al Ahsa Campus, Saudi Arabia. ATLAST ti 8 was used for systematic literature review and SPSS v23 obviously for data analysis. This was a new and novel study as the Pre-hospital ultrasound was not used before in the pre-hospital. On the other hand, the findings showed that the participants displayed a high level of interest in improving their knowledge and skills of using ultrasound during its application in the pre-hospital setting. It was also recommended to have more research in future on the subject

Nonhomologous end joining of complex DNA double-strand breaks with proximal thymine glycol and interplay with base excision repair

DNA double-strand breaks induced by ionizing radiation are often accompanied by ancillary oxidative base damage that may prevent or delay their repair. In order to better define the features that make some DSBs repair-resistant, XLF-dependent nonhomologous end joining of blunt-ended DSB substrates having the oxidatively modified nonplanar base thymine glycol at the first (Tg1), second (Tg2), third (Tg3) or fifth (Tg5) positions from one 3' terminus, was examined in human whole-cell extracts. Tg at the third position had little effect on end-joining even when present on both ends of the break. However, Tg as the terminal or penultimate base was a major barrier to end joining (>10-fold reduction in ligated products) and an absolute barrier when present at both ends. Dideoxy trapping of base excision repair intermediates indicated that Tg was excised from Tg1, Tg2 and Tg3 largely if not exclusively after DSB ligation. However, Tg was rapidly excised from the Tg5 substrate, resulting in a reduced level of DSB ligation, as well as slow concomitant resection of the opposite strand. Ligase reactions containing only purified Ku, XRCC4, ligase IV and XLF showed that ligation of Tg3 and Tg5 was efficient and only partially XLF-dependent, whereas ligation of Tg1 and Tg2 was inefficient and only detectable in the presence of XLF. Overall, the results suggest that promoting ligation of DSBs with proximal base damage may be an important function of XLF, but that Tg can still be a major impediment to repair, being relatively resistant to both trimming and ligation. Moreover, it appears that base excision repair of Tg can sometimes interfere with repair of DSBs that would otherwise be readily rejoined

Correlation and factors influencing knee pain status among patients who underwent sleeve gastrectomy in Saudi Arabia: A cross sectional study

Objective: The goal of this study was to see if there was a link between individuals who had a sleeve gastrectomy and their knee discomfort, as well as what factors could influence knee pain after a sleeve gastrectomy. Materials and Methods: The general population of Saudi Arabia was studied in this cross-sectional survey, which took place from August 2021 to February 2022. Only people who had had a sleeve gastrectomy and were experiencing knee discomfort were included in the research. Results: The results revealed that bariatric surgery had improved knee pain status in most of the participants (76%) while (12.1%) complained that the pain worsened after the surgery. The results also showed that nearly half of our participants (49.8%) that complain of knee pain have lost more than 35 kg after bariatric surgery, which illustrates the impact of a number of kilograms (kg) lost after bariatric surgery. Only (12.8%) of the participants considered physiotherapy as an intervention for their knee pain. Also, the results showed that severe pain was considerably more prevalent in the older age group and those with concomitant chronic disease. Conclusions: Our data revealed that a small percentage of participants had worsening knee discomfort, which might be connected to inactivity following sleeve gastrectomy surgery. As a result, we urge that further clinical studies be conducted to learn more about the exacerbation of knee pain after a gastrectomy

THE READING PERCEPTION OF MEDICAL STAFF ABOUT THE USE OF PREHOSPITAL ULTRASOUND

This study was a focus on the use of pre-hospital ultrasound in Saudi Arabia. Generally, ultrasound is used in a high frequency by health care providers in different countries within hospitals or pre-hospital. The main point of using the ultrasound was to reduce the time of diagnosis at the hospital and decrease the rate of mortality and morbidity. The study was a cross-sectional study and was used to assess the perception of medical staff about the use of pre-hospital ultrasound. This survey study had 130 participants, and 80 of them were agreed to involve in this study. It was conducted in King Abdulaziz Hospital of National Guards, Al Ahsa and College of Applied Medical Sciences, King Saud Bin Abdul Aziz University for Health Sciences, Al Ahsa Campus, Saudi Arabia. ATLAST ti 8 was used for systematic literature review and SPSS v23 obviously for data analysis. This was a new and novel study as the Pre-hospital ultrasound was not used before in the pre-hospital. On the other hand, the findings showed that the participants displayed a high level of interest in improving their knowledge and skills of using ultrasound during its application in the pre-hospital setting. It was also recommended to have more research in future on the subject