A SHORT REVIEW ON HERBAL PRODUCTS ACTING AS ANTI-HIV AGENTS

Over the previous decade, considerable advancement has been made in research on the regular items having hostility to HIV movement. An assortment of optional metabolites got from natural origin demonstrated mild to strong anti-HIV properties. Nature has consistently given a wellspring of medications to different sicknesses. Various therapeutic plants have been accounted for to have against HIV. The investigation of regular items in biomedical exploration is not an advanced idea. vast numbers of the best medicinal therapeutic drugs are extracted from natural products and concentrated in HIV/AIDS. The Biomedical review has a long history of disclosure depending on the screen of medicinal spices and conventional medicines. It is essential to remember the clinical study convention to conclude Therapies based on these herbal products combat the negative view of alternative medicine as therapeutic remedies. This review addressed different herbal products that are having anti-HIV properties

Defect Tracking System

The main purpose of this project is it is an online Bug Hawker system and which is used for providing the solutions to correct the errors. This application is a totally web based tool and any user can access this tool by registering into the software. This software works once we login into the software and we can choose the error what kind of error it is etc. from the dropdown list. This software also has the extra facilities like email notifications, generating the reports, user access control etc

IPOs as Catalysts for Retail Investor Wealth Creation: Evidence from the Indian Stock Market

The study delves into the dynamics of wealth creation for retail investors in the context of Initial Public Offerings (IPOs) within the Indian equity markets. Against the backdrop of a burgeoning retail investor base, the research offers a comprehensive analysis spanning April 2012 to December 2022, evaluating short-term and long-term IPO performance metrics. The study reveals nuanced insights into wealth creation dynamics by scrutinizing listing day returns, first-week to third-year returns, and market-adjusted returns vis-à-vis the Nifty50 Index. Notably, the research suggests that while IPOs exhibit promise with positive listing day returns, sustaining growth over extended horizons poses challenges. The hypothesis of inflation serving as a pragmatic hurdle rate for retail investors is explored, offering a novel perspective on wealth preservation. It also sheds light on the significant variability in the Real Rate of Returns (RRRs) among IPOs, with some contributing to wealth generation while others result in wealth erosion. This underscores the importance of retail investors carefully assessing and managing risks, emphasizing the need for prudent portfolio diversification and effective risk mitigation strategies, particularly over longer investment horizons

DRUG UTILISATION EVALUATION OF ANTIHYPERTENSIVES IN GERIATRIC PATIENTS IN A TERTIARY CARE HOSPITAL

Objective: Hypertension is a leading contributor to the global burden of cardiovascular morbidity and mortality. The main objective of the present study was to assess the drug utilization patterns of antihypertensives in geriatric patients in a teaching hospital. Methods: A Single centre Prospective Observational study was carried out for a period of three months in an out-patient department of Owaisi Hospital & Research Centre. Elderly patients who have been diagnosed with hypertension as per JNC-7 guidelines and patients receiving or prescribed with antihypertensive drugs were included. Results: A total of 100 prescriptions were analyzed during the three month study period. 72% of the patients were in the age group of 65-67 years and this was found to be higher in men 68%. During the study period 80% of the patients were Pre-Hypertensive systolic (80-89 mmHg) and Diastolic (120-139 mmHg) followed by Stage-I Hypertension and Stage-II Hypertension. The most common drug classes involved in the study was Calcium Channel Blockers 37% followed by Angiotensin II receptor antagonists 21% and the most commonly prescribed drugs in the study population were Amlodipine 37%, Losartan 11% and Telmisartan 10%. The most common anti-hypertensive fixed dose combination therapy involved in the study was Telmisartan + Hydrochlorothiazide 15% and most common two drug combination therapy involved in the study was Amlodipine + Atenolol 7% followed by Metoprolol + Amlodipine 1%. Conclusion: Our study shows that the most commonly prescribed drug classes involved were Calcium Channel Blockers followed by Angiotensin II receptor antagonists and the anti-hypertensive drug combinations among hypertensive patients were considerable and this practice positively impacted on the overall blood pressure control

Digitized Engineering Notebook

The GSURobotics.org is a Digitized Engineering web based application which will allow the students to upload projects details thru the website. Each team needs to create their account and can be able to create or edit their project details such as texts, images or even the team videos. It’s an annual robotics competition where in each team will be reviewed by a team of pioneers and awards will be facilitated to the team that shows creativity and innovation. The competition is completely online. Goals • Challenge students to apply skills in creative ways. • Encourage participation by the public and private firms. • Integrate technology and creativity skills. It’s a new application which can provide the following: • Competitions are open to all school clubs. • Each team can submit as many projects as they want. • There is no time limit for the projects. • Projects will be ranked for their creativity, structure, and their functions. • As per the project deadline the application will be released on April 17 2017. Methods or Algorithms: GSURobotics.com is a rock-solid web application and easy to navigate, dynamic web application with multiple features. We have planned to implement this project by using ASP.net technology for the front end and to store the data in the backend we will be using SQL server. The front page will guide for the team registration. Once the registration is done then the student can upload their project with the project documents, videos and images

Antidiabetic Activity of Vinca rosea Extracts in Alloxan-Induced Diabetic Rats

The present study was carried out to evaluate the antidiabetic activity of Vinca rosea methanolic whole plant extracts in alloxan induced diabetic rats for 14 days. The methanolic whole plant extract at high dose (500 mg/kg) exhibited significant anti-hyperglycemic activity than whole plant extract at low dose (300 mg/kg) in diabetic rats. The methanolic extracts also showed improvement in parameters like body weight and lipid profile as well as regeneration of β-cells of pancreas in diabetic rats. Histopathological studies reinforce the healing of pancreas, by methanolic Vinca rosea extracts, as a possible mechanism of their antidiabetic activity

Comprehensive Performance Measurement Methodology for Reverse Logistics Enterprise

Nowadays, due to increased competition caused by globalization and high rates of innovation supply chains continue to have shorter life-cycle products. More liberal return policies, increasing enforcement of take-back laws, heightened environmental regulations, increase in financial returns, good corporate image, increasing customer demands, have made enterprises face the challenges of strategically managing the returned and discarded products. Therefore, handling of product returns has led the reverse logistics activities to be effective and efficient. Efficiency of reverse logistics is achieved by reducing the waste, recapturing recovered value, reducing inventory investments, and optimizing the collection networks. Reverse logistics effectiveness allows enterprises an opportunity to improve competitiveness by building consumer confidence through handling of returned products, liberalized returns policies, operations of take-back networks, and green aspects of performance. But due to the intrinsic complexities of reverse logistics operations, such as uncertainty in quality, quantity, and timing of returns, makes the product returns process more complicated. The present literature on reverse logistics focuses on the factors that support the enterprises to manage and optimize their operations to remain competitive, but does not reflect upon the comprehensive performance measurement on how enterprises have to measure their reverse logistics activities. To contribute to the field, this research is carried out to study the performance measurement in reverse logistics enterprise to fill the gap in the literature. This dissertation presents a CRLEPMS - Comprehensive Reverse Logistics Enterprise Performance Measurement methodology to facilitate performance measurement and decision making for the enterprise involved in reverse logistics. It examines different performance measurement attributes and criteria for measuring reverse logistics performance. It investigates the inner and inter relationships among different criteria of attributes and also among clusters of attributes applying DEMATEL, FANP and AHP MCDM methods. Further, the enterprise computes the comprehensive overall performance index in order to benchmark its performance with best in class practices. The application of the CRLEPMS methodology provides the enterprises with a real world viewpoint of what and how performance attributes and measures impact the comprehensive overall performance index, so that they get feedback and continuously improve their product returns practices

PRICE DEMAND MODEL FOR A CLOUD CACHE

Cloud applications that offer data management services are emerging. Such clouds support caching of data in order to provide quality query services. The users can query the cloud data, paying the price for the infrastructure they use. Cloud management necessitates an economy that manages the service of multiple users in an efficient, but also, resource economic way that allows for cloud profit. Naturally, the maximization of cloud profit given some guarantees for user satisfaction presumes an appropriate price-demand model that enables optimal pricing of query services. The model should be plausible in that it reflects the correlation of cache structures involved in the queries. Optimal pricing is achieved based on a dynamic pricing scheme that adapts to time changes. This paper proposes a novel price-demand model designed for a cloud cache and a dynamic pricing scheme for queries executed in the cloud cache. The pricing solution employs a novel method that estimates the correlations of the cache services in an time-efficient manner. The experimental study shows the efficiency of the solution

Sales Management Portal

In any business organization, sales is the department that generates revenue. No matter how good your manufacturing operation is, how cutting-edge your technology is, how tight your financial goals are or how progressive and forward-thinking your management techniques are, you must still have a sales mechanism in place, or everything else is useless. Why is this project important? A sales management portal is a phenomenal way to explain the importance of marketing or sales within the organization. it involves the possible way for all the people to get connected and get the information they may need for potential sales. Indeed, portal is a doorway for the process of marketing and get to the next step of any business. What problem does it solves? This project will cover all the options about the selling activities, where management can easily access the detailed report about the sales team and managing their performance. Therefore, the management will have the option of accessing updated information through their DASHBOARD and can leave important notes to the employee. The other important benefit includes, all the information about the clients and the communication between the sales team and the managers will be easily accessible for future purposes. Does it provide a new application/service, replace an existing application/service, or enhance an existing application/service? This project will cover more focused functionalities, such as: USER FRIENDLY OPTIONS: the designed features used in this project is easily understandable to anyone. NOTES: this is an additional feature, where the sales team can leave their opinion or comments in order to know the management about the ongoing work, which in turn the management can give their feedbacks. OPPORTUNITY: in addition to above, there is another feature included in this project where the sales person can easily evaluate the possibility of having opportunities to finalize the initiation of project. The Sales Management Portal will be available for its final presentation and release before 5th December 2016

Phytochemical, elemental and biotechnological study of Cryptocarya latifolia

Background: Existing populations of Cryptocarya latifolia (Lauraceae) are rapidly declining as a consequence of their substitutive use for Ocotea bullata. The  uncontrolled and excessive removal of the bark and roots of this species has led to the death of many of these plants and may eventually result in its depletion in the natural habitat.Materials and Methods: The secondary metabolites from the leaves and fruits of C. latifolia were extracted using solvents of various polarities, isolated using column chromatography and identified using spectroscopic techniques. The in vitro free radical scavenging activity (antioxidant capacity) of selected phytocompounds at varied concentrations was determined by the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay. A propagation study of the species was also conducted.Results: The compounds isolated from the plant were the novel compound, α-pyrone (5-hexyltetrahydro-2H-pyran-2-one) and known compounds quercetin- 3-O-rhamnoside, β-sitosterol, copaene and nerolidol. The radical scavenging  activity of the isolated compounds indicated moderate to good anti-oxidant activity. Treatment of explants with BAP: NAA at 1.0:0.01 mg L-1 produced the highest percentage of shoots (94%) and longest shoot length (8.06 mm).Conclusion: This study validates the ethno-medicinal use of the plant and supports the replacement of bark and roots by leaves and fruits for the management and conservation of this declining plant species. The benefits of consuming the fruits are two-fold as they can also contribute to the recommended dietary allowances of most essential elements for the majority of individuals.Key words: secondary metabolites, antioxidants, bud break, nutrition