High Speed and Low Power Consumption Carry Skip Adder using Binary to Excess-One Converter

Arithmetic and Logic Unit (ALU) is a vital component of any CPU. In ALU, adders play a major role not only in addition but also in performing many other basic arithmetic operations like subtraction, multiplication, etc. Thus realizing an efficient adder is required for better performance of an ALU and therefore the processor. For the optimization of speed in adders, the most important factor is carry generation. For the implementation of a fast adder, the generated carry should be driven to the output as fast as possible, thereby reducing the worst path delay which determines the ultimate speed of the digital structure. In conventional carry skip adder the multiplexer is used as a skip logic that provides a better performance and performs an efficient operation with the minimum circuitry. Even though, it affords a significant advantages there may be a large critical path delay revealed by the multiplexer that leads to increase of area usage and power consumption. The basic idea of this paper is to use Binary to Excess-1 Converters (BEC) to achieve lower area and power consumption

Power Efficient and High Speed Carry Skip Adder using Binary to Excess One Converter

The design of high-speed and low-power VLSI architectures need efficient arithmetic processing units, which are optimized for the performance parameters, namely, speed and power consumption. Adders are the key components in general purpose microprocessors and digital signal processors. As a result, it is very pertinent that its performance augers well for their speed performance. Additionally, the area is an essential factor which is to be taken into account in the design of fast adders. Towards this end, high-speed, low power and area efficient addition and multiplication have always been a fundamental requirement of high-performance processors and systems. The major speed limitation of adders arises from the huge carry propagation delay encountered in the conventional adder circuits, such as ripple carry adder and carry save adder. Observing that a carry may skip any addition stages on certain addend and augend bit values, researchers developed the carry-skip technique to speed up addition in the carry-ripple adder. Using a multilevel structure, carry-skip logic determines whether a carry entering one block may skip the next group of blocks. Because multilevel skip logic introduces longer delays, Therefore, in this paper we examine The basic idea of this work is to use Binary to Excess- 1 converter (BEC) instead of RCA with Cin=1 in conventional CSkA in order to reduce the area and power. BEC uses less number of logic gates than N-bit full adder

Induction de sens pour enrichir des ressources lexicales

International audienceEn traitement automatique des langues, les ressources lexico-sémantiques ont été incluses dans un grand nombre d'applications. La création manuelle de telles ressources est consommatrice de temps humain et leur couverture limitée ne permet pas toujours de couvrir les besoins des applications. Ce problème est encore plus important pour les langues moins dotées que le français ou l'anglais. L'induction de sens présente dans ce cadre une piste intéressante. À partir d'un corpus de texte, il s'agit d'inférer les sens possibles pour chacun des mots qui le composent. Nous étudions dans cet article une approche basée sur une représentation vectorielle pour chaque occurrence d'un mot correspondant à ses voisins. À partir de cette représentation, construite sur un corpus en bengali, nous comparons plusieurs approches de clustering (k-moyennes, clustering hiérarchique et espérance-maximisation) des occurrences d'un mot pour déterminer les différents sens qu'il peut prendre. Nous comparons nos résultats au Bangla WordNet ainsi qu'à une référence établie pour l'occasion. Nous montrons que cette méthode permet de trouver des sens qui ne se trouvent pas dans le Bangla WordNet

EVALUATION OF EFFICACY AND SAFETY OF NIGELLA SATIVA OIL SUPPLEMENTATION IN PATIENTS OF CHRONIC KIDNEY DISEASE

ABSTRACTObjective: To evaluate efficacy and safety of add-on therapy of Nigella sativa oil in patients of stage 3 and 4 of chronic kidney disease (CKD).Materials and Methods: The study was conducted in a tertiary care center of north India in stage 3 and 4 patients of CKD. It was a prospective,comparative, and open label study. Patients were randomly divided into two interventional groups. Group I (Control) received conservativemanagement of CKD while Group II (Test) received conservative management along with N. sativa oil (2.5 mL, per orally, once daily) for 12 weeks.Hemogram and renal function tests were done, and adverse events were recorded at 0, 6, and 12 weeks of treatment.Results: After 12 weeks of treatment, there was a progressive improvement in clinical features and biochemical parameters in both the groups, but itwas more marked in the test group compared to control group. Both groups showed gradual improvement in the biochemical parameters as comparedto their pre-treated values which were more marked in N. sativa oil supplemented group. There was a reduction in blood glucose, blood urea, serumcreatinine, and 24-hr total urine protein. There was an increase in hemoglobin, 24-hr total urine volume, and glomerular filtration rate.Conclusion: N. sativa oil supplementation along with conservative management is efficacious and safe in averting the progression of disease in stage 3and 4 patients of CKD.Keywords: Chronic kidney disease, Nigella sativa oil, End-stage renal disease, Glomerular filtration rate

Comparative evaluation of doxofylline and theophylline in patients of mild bronchial asthma

Background: Asthma is common chronic disease worldwide. Methylxanthines has been used in the treatment of asthma. The study was undertaken to compare two Methylxanthines theophylline and doxofylline at doses recommended and commonly used in clinical practice in Mild Bronchial Asthma Patients.Methods: Study was conducted in patients of Mild Bronchial Asthma in TB and chest disease department of a medical college hospital. It was randomized, prospective and open label. A total of 107 patients were divided in two group .Group I was administered 400 mg theophylline SR once daily and group II was administered doxofylline 400 mg twice a day orally. Spirometric variables symptom score, and adverse effects were recorded on day 0, 7 and 21 of therapy. Data were compared and analysed using SPSS version 16.Results: Results of the study showed that there was significant improvement in spirometric variables and clinical symptom score compared to pretreatment values after medication in both groups on 7th and 21st days of treatment. But there was no statistically significant difference between improvement in theophylline and doxofylline groups with respect to spirometric variables and symptom score. There was no significant difference in two groups with respect to side effects (p>0.05).Conclusions: It is concluded in Patients of mild Bronchial Asthma Theophylline and doxofylline improve the spirometric and clinical symptoms and doxofylline has no advantage over theophylline in terms of either efficacy or safety on the doses commonly used in current clinical practice

Role of rhubarb and α-keto analogues of essential amino acids supplementation in halting progression of chronic kidney disease

Background: Chronic kidney disease (CKD) is an emerging chronic disease due to rapidly increasing incidence of diabetes and hypertension worldwide. Newer drugs are being searched which can stop nephron damage and are cost effective. This study was undertaken to compare the efficacy and safety profile of rhubarb and α-keto analogues of essential amino acids supplementation in patients of chronic kidney disease.Methods: A prospective comparative study was conducted in patients of chronic kidney disease attending Renal Clinic of a tertiary care centre. Randomization of patients was done into three interventional groups: conservative management along with placebo was given in first group (Control); conservative management along with Rhubarb capsule (350 mg, thrice daily) was given in second group (Rhubarb) and conservative management along with α-keto analogues of essential amino acids (600 mg, thrice daily) was given in third group (KAA). The treatment was given for 12 weeks. Clinical and biochemical parameters were assessed at 0, 4, 8 and 12 weeks of treatment.Results: Patients of all three groups showed gradual improvement in clinical features and biochemical parameters as compared to their pre-treated values which was more marked in KAA supplemented group. There was reduction in: fasting blood glucose (12.51%, 19.15% and 20.78%), PPBG (14.80%, 19.00% and 20.89%), serum creatinine (25.00%, 30.54% and 39.52%), blood urea (25.55%, 33.64% and 38.09%), and 24-hour total urine protein (TUP) (19.80%, 30.18% and 38.34%) in Group I, II and III respectively. There was increase in: haemoglobin level (12.64%, 14.99% and 19.77%), 24-hour total urine volume (TUV) (19.41%, 28.82% and 33.32%) and GFR (22.6%, 46.5% and 49.2%) in Group I, II and III respectively. Rhubarb and KAA supplementations were safe and well-tolerated.Conclusions: KAA is more effective than Rhubarb as add on therapy with conservative management in patients of chronic kidney disease

Clinical evaluation of efficacy and safety of α-keto analogs of essential amino acids supplementation in patients of chronic kidney disease

Background: The objective was to evaluate the efficacy and safety of α-keto analogs of essential amino acids (KAA) as a supplement in chronic kidney disease (CKD).Methods: A prospective comparative study was conducted in patients of CKD of a tertiary care center of North India. Patients were randomly divided into two interventional groups. Group I (control) was advised conservative management and placebo while Group II (KAA) given conservative management along with KAA (600 mg, thrice daily) for 12 weeks. Hemogram, renal function tests, lipid profiles were done, and adverse effects were recorded at 0, 4, 8, and 12 weeks of treatment.Results: There was progressive improvement in clinical features in both groups after 12 weeks of treatment, but KAA group showed more marked improvement as compared with the control group. Both groups showed gradual improvement in the biochemical parameters as compared to their pre-treated values, which was more marked in KAA supplemented group. There was a reduction in blood glucose, blood urea, serum creatinine, and 24 h total urine protein. There was an increase in hemoglobin, 24 h total urine volume and glomerular filtration rate. KAA group showed significant (p<0.05) improvement in lipid profiles as compared with the control group. There was no statistical difference in two groups with respect to side-effects (p>0.05).Conclusion: KAA supplementation along with conservative management is efficacious and safe in preventing the progression of disease in patients of CKD