The effect of linum usitatissimum (flax seed) and nigella sativa oil on selected oral pathogen (Comparative study)

Nowadays the people are more concerned, conscious and are more inclined to use natural products and preference change to herbal instead of synthetic medication is because of sever side effects of some materials or facing the potential risk of bacterial resistance. Bacteria and their products play an important role in the pathogenesis of polio-periapical disease. Predominant microbial groups often isolated from infected root canals are the aerobic and facultative anaerobic organisms. Linum usitatissimum (flaxseed, flax plant) Cultivated for domestic use As dietary supplement because of multitudinous effect on human health Also used to treat constipation Nigella sativa (Habbah Sawda or Habbat el Baraka) Black cumin herb Translated as seed of blessing Potent anti inflammatory, anticancer, anti infertility, anti diabetic, antimicrobial, antihistamine and anti hypertensive effect

Potential antibacterial effects of flaxseed and Nigella sativa extracts on 11 streptococcus pyogenes

Antibiotic resistance is a major global problem, associated with inadvertent drug usage. Herbal interventions are a therapeutic strategy that warrants greater research attention. Flaxseed and Nigella sativa are well recognized original super foods that have demonstrated potent anti-microbial and anti-biofilm activities. In the oral cavity, the bacterial population is a result of the dynamic relationship between pathogens and commensals Streptococcus pyogenes is an important global human Gram-positive pathogen that causes a wide variety of acute infections, it is highly virulent since it has the ability overcome the host defence system. This in vitro study aims to evaluate antimicrobial activity of flaxseed and Nigella sativa extract against S. pyogenes. Ethanolic extract of flaxseed and Nigella sativa extracts were prepared and the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against S. pyogenes was estimated. The results of this study show that both extracts exhibited antibacterial activity against S. pyogenes. Present study demonstrated the bactericidal activity of both extracts which can be an adjunct to the future natural anti-bacterial therapy

Linum usitatissimum antibacterial activity on Pseudomona Aerigenosa in-vitro study

Flaxseed comes from the flax plant (Linum usitatissimum), which has been cultivated for domestic use since prehistoric times. Pseudomonas aeruginosa is a Gram-negative bacterium has the ability to survive in adverse environments and develop multiple antibiotic resistance mechanisms. This study aims to evaluate the susceptibility of Pseudomonas aeruginosa (P. aeruginosa) in vitro to the ethanolic extract obtained from flax seed. This is a laboratory experimental in vitro study using P. aeruginosa cultured in nutrient agar. The pathogen then was inoculated in nutrient based broth and incubated for 24hours. Flaxseed extract efficacy was tested by measurement of the zone of inhibition. The result of the extracts antimicrobial activities were compared with streptomycin as positive control and DMSO as negative control. The statistical analysis was done by using SPSS19.There is positive antibacterial effects of flaxseed extract against Pseudomona Aerigenosa and it was comparable in efficacy to that of Streptomycin. This study concludes that flaxseed extract can help in inhibiting Pseudomona Aerigenosa activity. The implication of this result will be useful in propagating the use of natural based product as therapeutic drug against the chemical synthetic products. The results of the present study scientifically validate the inhibitory capacity of Linum usitatissimum as antibiotic against one of the most resistant pathogens and contribute towards the development of new treatment options based on natural products

The antibacterial effect of flaxseed extract on selective oral pathogens - comparative in vitro study

Introduction: Flaxseed from the flax plant (Linum usitatissimum), which has been cultivated for domestic use since prehistoric times. This study aims to investigate presence of antibacterial effect of flaxseed extract against selected oral pathogen in-vitro. Materials and Methods: This is a laboratory experimental in vitro study using selected oral pathogens cultured in nutrient agar. The pathogens then were inoculated in nutrient based broth and incubation for 24hours. Flaxseed extract efficacy was tested by measurement of the zone of inhibition. The antibacterial activities were compared with streptomycin as positive control and DMSO as negative control. The statistical analysis was done by using SPSS. Results: There is positive antibacterial effects of flaxseed extract against Streptococcus mutans, Streptococcus Pyogenes, Pseudomona Aerigenosa and was comparable in efficacy to that of Streptomycin. Conclusion: This study concludes that flaxseed extract has antibacterial activity ageist selective oral pathogens. The implication of this result will be useful in propagating the use of natural based product as therapeutic drug against the chemicalsynthetic products. This study recommends the use of natural herbal product to have the equal potential while negating the unwanted side effects towards humans’ body

The antimicrobial effect of flax seed on pseudomonas aeruginosa

Flaxseed comes from the flax plant (Linum usitatissimum), which has been cultivated for domestic use since prehistoric times. Pseudomonas aeruginosa is a Gram-negative bacterium has the ability to survive in adverse environments and develop multiple antibiotic resistance mechanisms. This study aims to evaluate the susceptibility of Pseudomonas aeruginosa (P. aeruginosa) In-vitro to the ethanolic extract obtained from flax seed. This is a laboratory experimental in vitro study using P. aeruginosa cultured in nutrient agar. The pathogen then was inoculated in nutrient based broth and incubated for 24hours. Flaxseed extract efficacy was tested by measurement of the zone of inhibition. The result of the extracts antimicrobial activities were compared with streptomycin as positive control and DMSO as negative control. The statistical analysis was done by using GraphPad PRISM version 6. There is positive antibacterial effects of flaxseed extract against Pseudomonas aeruginosa and it was comparable in efficacy to that of Streptomycin. This study concludes that flaxseed extract can help in inhibiting Pseudomonas aeruginosa activity. The implication of this result will be useful in propagating the use of natural based product as therapeutic drug against the chemical synthetic products. The results of the present study scientifically validate the inhibitory capacity of Linum usitatissimum as antibiotic against one of the most resistant pathogens and contribute towards the development of new treatment options based on natural products