Mineralogy and Geochemistry of the Guenfouda Clay Deposit, Jerada Province, Northeastern Morocco

peer reviewedThe Guenfouda clay deposit is located at about 36km to the southwest of Oujda city and 6km to the south of Guenfouda village. It belongs to the Jerada Province of the northeastern Morocco and hosted within the Upper Visean calc-alkaline dacite lava interbedded within a schisto-volcanic complex. This deposit is mined for more than 15 years and the product being mainly used for refractories and industrial ceramics. This clay deposit is funnel or trough-like in form, narrowing downwards and display a E–W trend, which follows the major dextral strike-slip fault that passes through the south of the deposit. Based on mineral assemblages, four lateral alteration zones were defined from the north to south parts of the deposit: the Illite zone, the Pyrophyllite-illite zone, the Pyrophyllite zone and the Quartz zone. The presence of high-temperature minerals such as pyrophyllite, diaspore, the alteration zonation pattern and the chemical characteristics are diagnostic of hypogene origin. However, the variation diagrams, Zr vs TiO2 and P2O5 vs SO3 as well as the values of the chemical Index of Weathering (CIW) and the Alteration Index (AI) revealed a mixed type. It seems that the genesis of Guenfouda clay deposit was first controlled by the eastwest strike-slip faults, which brought ascending hydrothermal solutions that led to clay formation and finally, the weathering processes have continued and extended the argillization

Molecular detection of Epstein-Barr virus among Sudanese patients diagnosed with Hashimoto’s thyroiditis

Objectives: Hashimoto’s thyroiditis (HT) is the most common cause of hypothyroidism. The exact mechanism initiating the development of HT is not yet clear. This study aimed to investigate the correlation between HT and the presence of Epstein-Barr virus (EBV) in a Sudanese population. Results: EBV-LMP1 was detected in 11.1% of HT cases, which is consistent with previous studies. Studies have reported a wide range of frequencies indicating the presence of EBV in HT, and patients with autoimmune thyroiditis have increased titers of anti-EBV antibodies in their sera compared to healthy subjects. Intrathyroidal EBV-infected B cells may be responsible for the increased risk of development of B-cell lymphoma in the thyroid gland in patients with autoimmune thyroiditis. Our study suggests that regular follow-up is necessary for patients diagnosed with HT and are positive for EBV, as antiviral therapy is not applicable due to the risk of thyroid dysfunction. The study suggests an association between EBV and HT, but causation cannot be determined. The study also highlights the need for further research to determine the viral role and correlate it with the severity and progression of HT.</p

Molecular detection of Epstein-Barr virus among Sudanese patients diagnosed with Hashimoto’s thyroiditis

Objectives: Hashimoto’s thyroiditis (HT) is the most common cause of hypothyroidism. The exact mechanism initiating the development of HT is not yet clear. This study aimed to investigate the correlation between HT and the presence of Epstein-Barr virus (EBV) in a Sudanese population. Results: EBV-LMP1 was detected in 11.1% of HT cases, which is consistent with previous studies. Studies have reported a wide range of frequencies indicating the presence of EBV in HT, and patients with autoimmune thyroiditis have increased titers of anti-EBV antibodies in their sera compared to healthy subjects. Intrathyroidal EBV-infected B cells may be responsible for the increased risk of development of B-cell lymphoma in the thyroid gland in patients with autoimmune thyroiditis. Our study suggests that regular follow-up is necessary for patients diagnosed with HT and are positive for EBV, as antiviral therapy is not applicable due to the risk of thyroid dysfunction. The study suggests an association between EBV and HT, but causation cannot be determined. The study also highlights the need for further research to determine the viral role and correlate it with the severity and progression of HT.</p

L’histoire éruptive du volcan monogénique quaternaire de Timahdite (Moyen Atlas, Maroc)

Le volcan de Timahdite fait partie de la province volcanique alcaline quaternaire du Moyen Atlas et se compose d’un maar à cratère grossièrement elliptique entouré d’un anneau de tufs, au sein duquel se niche un cône strombolien. Les travaux de cartographie, pétrographie, morphoscopie et granulométrie réalisés sur les dépôts volcaniques de cet appareil montrent que son édification s’est déroulée en quatre phases éruptives qui se relayent dans le temps : (I) une phase phréatomagmatique, (II) une première phase effusive à l’origine du lac de lave, (III) une phase strombolienne et (IV) la phase effusive terminale. La phase phréatomagmatique, engendrée par l’interaction magma-eau, est constituée par des déferlantes basales de plus en plus sèches et entrecoupées de niveaux de retombées. La première phase effusive est représentée par un lac de lave basaltique qui colmate le cratère du maar et déborde vers l’est pour se canaliser dans le lit de l’Oued Guigou. La phase strombolienne se met en place à la suite d’une courte pause représentée par une discordance angulaire synchrone de la mise en place du lac de lave. Cette troisième phase est matérialisée par un cône de scories avec une séquence pyroclastique dominée par des retombées stromboliennes auxquels sont associées des bombes fusiformes et en bouse de vache. La phase effusive terminale correspond à la mise en place de la coulée basaltique terminale et sa brèche qui nappent le sommet et le flanc sud-est du cône. Outre les causes volcanologiques et tectoniques, la variabilité du bilan hydrique de l’Oued Guigou a pu jouer un rôle majeur dans la dynamique de construction du volcan de Timahdite, influençant largement les dynamismes éruptifs et les modalités de dépôts.The Timahdite volcano is part of the Middle Atlas quaternary alkaline volcanic province and consists of a roughly elliptical crater maar surrounded by a tuff ring within which is edified a Strombolian cone. The cartography, petrography, morphoscopy and granulometry work carried out on the volcanic deposits of this edifice show that its construction took place in four eruptive phases which are relayed in time: (I) a phreatomagmatic phase, (II) a first effusive phase at the origin of the lava lake, (III) a Strombolian phase and (IV) the second effusive phase. The phreatomagmatic phase, generated by the magma-water interaction, consists of increasingly dry base surge interstratified with fallout levels. The first effusive phase is represented by a basalt lava lake which overflows the crater of the maar and pours out to the east and channeled into the Oued Guigou valley. The Strombolian phase is set up following a short pause represented by an angular unconformity. This third phase is materialized by a scoria cone with a pyroclastic sequence dominated by Strombolian fallout with ellipsoidal and cow pie bombs. The second effusive phase corresponds to the setup of the second basalt flow and its breccia which cover the top and the south-east flank of the cone. Besides the volcanological and tectonic causes, the variability of the water balance of Oued Guigou could play a major role in the dynamics of construction of the Timahdite volcano, largely influencing the eruptive dynamics and the deposits modalities

Geomorphological Classification of Monogenetic Volcanoes and Its Implication to Tectonic Stress Orientation in the Middle Atlas Volcanic Field (Morocco)

The Middle Atlas Volcanic Field (MAVF) covers an area of 1500 km2, with a total erupted volume of solid products (e.g., Dense Rock Equivalent or DRE) estimated to be more than 80 km3. The MAVF comprises 87 monogenetic basaltic volcanoes of Tertiary-Quaternary age as scoria cones (71%) and maars (29%). These monogenetic basaltic volcanoes have various morphologies (e.g., circular, semi-elliptic, elliptic in map views). They can be isolated or form clustered monogenetic complexes. They are largely grouped in the Middle Atlas, in an intraplate geotectonic context forming two distinct major alignments (N160&ndash;170&deg; and N40&ndash;50&deg;), each closely associated with regional structural elements. By the best estimates, the preserved bulk pyroclastic products do not exceed 0.7 km3, and they show large textural and componentry diversity (e.g., bedded/unbedded, coarse/fine, dense/scoriaceous fallout and pyroclastic density current deposit, etc.). Lava flows also demonstrate great variety of preserved surface textures, including p&#257;hoehoe, &lsquo;a&rsquo;&#257;, and clastogenic types. Morphostructural features of lava flows linked to lava flow dynamics have also been recognized, and the presence of hornitos, columnar jointed basaltic flow units, lava tubes, tumuli, and clastogenic lava flows have been recognized and mapped. Some half-sectioned dykes expose interior parts of magmatic shallow feeding pipes. The current morphology of the volcanoes of the MAVF reflects various syn- and post-eruptive processes, including (1) erosional features due to weathering, (2) gravitational instability during and after volcanic activity, (3) vegetation impact, and (4) successive burial of lava flows. The documented volcanic features of this typical monogenetic volcanic field form the core of the region&rsquo;s geoheritage elements and are considered to be unique in the new African geoheritage context. Hence, they will likely form the basis of future geotourism, geoeducation, and geoconservation ventures

Geomorphological Classification of Monogenetic Volcanoes and Its Implication to Tectonic Stress Orientation in the Middle Atlas Volcanic Field (Morocco)

The Middle Atlas Volcanic Field (MAVF) covers an area of 1500 km2, with a total erupted volume of solid products (e.g., Dense Rock Equivalent or DRE) estimated to be more than 80 km3. The MAVF comprises 87 monogenetic basaltic volcanoes of Tertiary-Quaternary age as scoria cones (71%) and maars (29%). These monogenetic basaltic volcanoes have various morphologies (e.g., circular, semi-elliptic, elliptic in map views). They can be isolated or form clustered monogenetic complexes. They are largely grouped in the Middle Atlas, in an intraplate geotectonic context forming two distinct major alignments (N160–170° and N40–50°), each closely associated with regional structural elements. By the best estimates, the preserved bulk pyroclastic products do not exceed 0.7 km3, and they show large textural and componentry diversity (e.g., bedded/unbedded, coarse/fine, dense/scoriaceous fallout and pyroclastic density current deposit, etc.). Lava flows also demonstrate great variety of preserved surface textures, including pāhoehoe, ‘a’ā, and clastogenic types. Morphostructural features of lava flows linked to lava flow dynamics have also been recognized, and the presence of hornitos, columnar jointed basaltic flow units, lava tubes, tumuli, and clastogenic lava flows have been recognized and mapped. Some half-sectioned dykes expose interior parts of magmatic shallow feeding pipes. The current morphology of the volcanoes of the MAVF reflects various syn- and post-eruptive processes, including (1) erosional features due to weathering, (2) gravitational instability during and after volcanic activity, (3) vegetation impact, and (4) successive burial of lava flows. The documented volcanic features of this typical monogenetic volcanic field form the core of the region’s geoheritage elements and are considered to be unique in the new African geoheritage context. Hence, they will likely form the basis of future geotourism, geoeducation, and geoconservation ventures

Complex monogenetic volcano in karst setting: lechmine N'kettane volcano (Middle Atlas, Morocco)

The Lechmine N'kettane is a Quaternary volcano, located within the Middle Atlas Volcanic Field (MAVF) in central Morocco. It is built on the faulted contact between Liassic limestone and Plio-Quaternary fluvio-lacustrine deposits. In map-view it consists of an elliptical maar crater, surrounded by a tephra ring, within which a scoria cone is nested in its northern crater zone. The Lechmine N'Kettane volcano is monogenetic in the sense of its small eruptive product volume and lack of evidence of significant time breakthrough it grows. The volcano formed from an eruptive locus that migrated laterally and vertically within the short duration of the eruption in a zigzagging pattern, along a complex set of generally NE-SW and NW-SE-trending faults. It represents a perfect example of how a volcano form and evolve under the influence of a combination of specific factors such as the lithological characteristics of the substrate, its hydrogeological parameters, magma flux and the local structural framework of the country rocks. The petrographic, granulometric and morphological (including terrain modelling) analyses of the Lechmine N'kettane pyroclastic deposits show that it was constructed in four eruptive phases with variable eruptive styles. The first, relatively dry, phreatomagmatic phase, that took place on a NE-SW fault in the northeastern part of the crater, was generated by the interaction between the ascending basaltic magma with meteoric water in the karst aquifer hosted by the Liassic limestone. The second phase is represented by a magmatic scoria fallout deposit whose explosion locus moved westward, along the same NE-SW fault. During the third phase, the explosion center migrated southward, along a NNW-SSE fault, and produced the last phreatomagmatic event by interaction of magma and water-saturated Plio-Quaternary sediment. The fourth eruptive phase is a purely scoria event, corresponding to the construction of the nephelinitic scoria cone in the northwestern part of the tephra ring. Between eruptive products formed in respective eruptive phases no evidence was recognized to establish significant time gaps between their formation.publishe

IFNL4 rs12979860 polymorphism influences HBV DNA viral loads but not the outcome of HBV infection in Moroccan patients

International audienceObjectivesThe interferon (IFN) is known to bridge innate and adaptive immune responses, and to play a critical role particularly against hepatitis B virus (HBV) infection. Defects in IFN signals may result, therefore, in attenuated responses against HBV. Accordingly, polymorphisms in genes coding for immune response effectors may affect the clinical outcome of HBV infection. We analyzed the putative association between IFNL4 rs12979860 polymorphism and the outcome of HBV infection in Moroccan patients.MethodsIn this study, 237 chronic HBV (CHB) patients and 129 spontaneously resolved HBV (SRB) individuals were enrolled and genotyped using a predesigned Taqman allelic discrimination assay.ResultsOur data show a significant increase of HBV DNA loads in patients with IFNL4 rs12979860 CC genotype compared to patients with CT and TT genotypes (p = 0.0008). However, there was no consistent association between IFNL4 rs12979860 polymorphism and the outcome of HBV infection.ConclusionsAlthough IFNL4 rs12979860 polymorphism seems to modulate circulating HBV DNA levels, it is disconnected from chronic disease progression. This observation suggests that the role of rs12979860 in liver disease is restricted to viral control and inactive in the deleterious immune pathology that affects liver tissue. Taken together, our data suggest that rs12979860 CC genotypes could be useful as a predictor of success or failure of IFN-based therapy in chronic HBV-infected patients