The comparison between presenting symptoms of ovarian cancer and other abdominal - pelvic cancers

Introduction: Diagnostic delays of ovarian cancer, has been attributed to the lack of a reliable and cost-effective screening test and presumption that ovarian cancer is  symptomatic in the early stages. To investigate presenting symptoms of ovarian cancer and compare with symptoms of other abdominal-pelvic cancersMethods: We reviewed the medical records of all women with abdominal-pelvic cancers between March, 2003 and March, 2005 in Shiraz medical centers to compare, presenting symptoms of ovarian cancer and other abdominal-pelvic cancers.Results: Of 168 women with a diagnosis of abdominal-pelvic cancers, ovarian cancer was diagnosed for 22 women. (Stage I: 0, Stage II: 2, Stage III: 10, Stage IV: 7 and 3 patientswithout staging.) The mean age of patients with ovarian cancer was 51/6.The sensation of abdominal mass was more common in women with ovarian cancer than other abdominalpelvic cancers (P=0.00l). Constipation was documented in the patients with colon cancer more than women with ovarian cancer (P=0.012), whereas urinary symptoms were more common in patients with ovarian cancer (P=0.004).Although the women with bladder cancer complained from urinary problems more than who had ovarian cancer (P=0.00l), but defecation problems and abdominal pain were more detected in patients with ovarian cancer (p=0.05). Conclusion: The most common cases of ovarian cancer present in the end stage that usually have poor prognosis. It can be associated to both patient and healthcare factors. This cancer is associated with many symptoms, but few symptoms are related to reproductive system. Sensation of abdominal mass, abdominal pain and urinary and defecation problems are the symptoms that can be associated with this cancer.Key words: Presenting Symptoms, Ovarian Cancer, and Abdominal-Pelvic Cancers

Chlamydia trachomatis in women with full-term deliveries and women with abortion

Problem statement: There are some documents which support the role of some certain infections such as Chlamydia trachomatis in spontaneous abortion. As there were not data about role this bacterium in abortion in this area of IRAN, this study was conducted to evaluate the prevalence of Chlamydia trachomatis in women with abortion and compare it with healthy women with no previous history of abortion. Approach: This case-control study was carried out in Shariatee hospital of Hormozgan University of medical sciences, during 2004-2005. A number of 220 women with definite diagnosis of previous abortion and 200 matched women with normal full term delivery and negative history of miscarriage as controls were studied as case and control groups. All obtained PAP smears from the case and the control groups were then tested using Immunoflourescent method for detection of Chlamydia trachomatis. Data was analyzed, using SPSS software (chi square and t-test). Results: The prevalence of positive direct immunofluorescent test on PAP smears indicating the presence of Chlamydia trachomatis was 56 (25.45) in women with abortion comparing to 13 (5.20) in women in control group, the difference was significant (p = 0.0001). Conclusion: This study showed Chlamydia trachomatis is an important causative agent for abortion in this area of IRAN. © 2010 Science Publications