Prospectus, March 13, 1985

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Prospectus, February 27, 1985

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Prospectus, October 3, 1984

FEMINIST MIND SEEN AS ANSWER FOR WORLD PROBLEMS; PC Digest; Blood Drive successful; \u27Wager opens to rave reviews\u27; 7 senators elected; Staff Profile-Kathy Hubbard Entertainment editor; Reaching mountain top not always goal; Degree still important asset; PC Happenings; Small Business Workshop planned; EMT Workshop scheduled; Parenting programs at Parkland; Health Programs focus on smoking, fitness and skin; Circle K exists to help; Gold struck in Arthur; Responsibility for self is common difficulty; Parkland enrollment follows trend; Woods hosts sports show; Creative Corner...Especially for you!!; The Meaning of I; The Last Goodbye; Advice from the Dueodenum; Almost There; Freedom; Doom-but whose?; Too Big for Me; Lady; The Ballad of Sue and Joe; Love Lost; Climbing the Mountain; Photographer wins in national competition; Student Profile-Carol DeVoss-newly elected senator \u27I\u27d like to see more student participation.\u27 Approximately 200 out of about 8,500 voted; Classifieds; Why are women obsessed?; New shows begin; Campbell\u27s a singin\u27 country boy; September love; Lady Cobras concentrate, win two; Bowlers Pin; IM Volleyball; IM Basketball; IM Football; Cross Country action; Wisdom, age to determine \u2785 Cobras baseball success; Golf actionhttps://spark.parkland.edu/prospectus_1984/1010/thumbnail.jp

Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy.

During early pregnancy, decidual innate lymphoid cells (dILCs) interact with surrounding maternal cells and invading fetal extravillous trophoblasts (EVT). Here, using mass cytometry, we characterise five main dILC subsets: decidual NK cells (dNK)1-3, ILC3s and proliferating NK cells. Following stimulation, dNK2 and dNK3 produce more chemokines than dNK1 including XCL1 which can act on both maternal dendritic cells and fetal EVT. In contrast, dNK1 express receptors including Killer-cell Immunoglobulin-like Receptors (KIR), indicating they respond to HLA class I ligands on EVT. Decidual NK have distinctive organisation and content of granules compared with peripheral blood NK cells. Acquisition of KIR correlates with higher granzyme B levels and increased chemokine production in response to KIR activation, suggesting a link between increased granule content and dNK1 responsiveness. Our analysis shows that dILCs are unique and provide specialised functions dedicated to achieving placental development and successful reproduction

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Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy

Abstract: During early pregnancy, decidual innate lymphoid cells (dILCs) interact with surrounding maternal cells and invading fetal extravillous trophoblasts (EVT). Here, using mass cytometry, we characterise five main dILC subsets: decidual NK cells (dNK)1–3, ILC3s and proliferating NK cells. Following stimulation, dNK2 and dNK3 produce more chemokines than dNK1 including XCL1 which can act on both maternal dendritic cells and fetal EVT. In contrast, dNK1 express receptors including Killer-cell Immunoglobulin-like Receptors (KIR), indicating they respond to HLA class I ligands on EVT. Decidual NK have distinctive organisation and content of granules compared with peripheral blood NK cells. Acquisition of KIR correlates with higher granzyme B levels and increased chemokine production in response to KIR activation, suggesting a link between increased granule content and dNK1 responsiveness. Our analysis shows that dILCs are unique and provide specialised functions dedicated to achieving placental development and successful reproduction

Distinctive phenotypes and functions of innate lymphoid cells in human decidua during early pregnancy

Abstract: During early pregnancy, decidual innate lymphoid cells (dILCs) interact with surrounding maternal cells and invading fetal extravillous trophoblasts (EVT). Here, using mass cytometry, we characterise five main dILC subsets: decidual NK cells (dNK)1–3, ILC3s and proliferating NK cells. Following stimulation, dNK2 and dNK3 produce more chemokines than dNK1 including XCL1 which can act on both maternal dendritic cells and fetal EVT. In contrast, dNK1 express receptors including Killer-cell Immunoglobulin-like Receptors (KIR), indicating they respond to HLA class I ligands on EVT. Decidual NK have distinctive organisation and content of granules compared with peripheral blood NK cells. Acquisition of KIR correlates with higher granzyme B levels and increased chemokine production in response to KIR activation, suggesting a link between increased granule content and dNK1 responsiveness. Our analysis shows that dILCs are unique and provide specialised functions dedicated to achieving placental development and successful reproduction