104 research outputs found

    CLIC QD0 "Short Prototype" Status

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    This paper gives the status design and procurement for the "short prototype" of the QD0 hybrid magnet for CLIC Final Focus system.Comment: 9 pages, Contribution to LCWS11 Workshop Granada, Spain 201

    Status of CLIC MBQ and DBQ Prototypes Procurement

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    This paper gives the status of studies, design and prototype procurement for the magnets needed for the CLIC R&D and for the LAB and CLEX Test Programs.Comment: 9 pages. Contribution to LCWS11 Workshop Granada, Spain, 201

    Survey: Women and California Law

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    This survey of California case law and legislation is a regular feature of the Women\u27s Law Forum. The survey summarizes recent California Supreme Court decisions, courts of appeal decisions, and new legislation which are of special importance to women. The focus of the survey is on presenting issues most pertinent to women, rather than on analyzing all issues raised in each case or bill. The survey period for cases in this issue is March 1, 1981 through February 28, 1982. Summaries of significant legislation enacted between October 1, 1980 and December 31, 1981 are also included

    A New QF1 Magnet for ATF3

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    Two high field quality quadrupole magnets QF1FF and QD0FF are required for the final focus system of the ATF3. In this paper we focus on the design of the QF1FF magnet. The proposed design is a permanent magnet quadrupole (PMQ) with adjustable strength. Alternative solutions such as conventional electromagnetic quadrupole (EMQ) and a hybrid quadrupole (combination of permanent magnet and electromagnet) are also presented and briefly discussed.Comment: 11 pages, Contribution to LCWS11 Workshop Granada, Spain 201

    Thermal effects compensation and associated uncertainty for large magnet assembly precision alignment

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    Big science and ambitious industrial projects continually push technical requirements forward beyond the grasp of conventional engineering techniques. An example of these are the extremely tight micrometric assembly and alignment tolerances required in the field of celestial telescopes, particle accelerators, and the aerospace industry. Achieving such extreme requirements for large assemblies is limited, largely by the capability of the metrology used, namely, its uncertainty in relation to the alignment tolerance required. The current work described here was done as part of Maria Curie European research project held at CERN, Geneva. This related to future accelerators requiring the spatial alignment of several thousand, metre-plus large assemblies to a common datum within a targeted combined standard uncertainty (uctg(y)) of 12â€ŻÎŒm. The current work has found several gaps in knowledge limiting such a capability. Among these was the lack of uncertainty statements for the thermal error compensation applied to correct for the assembly's dimensional instability, post metrology and during assembly and alignment. A novel methodology was developed by which a mixture of probabilistic modelling and high precision traceable reference measurements were used to quantify the uncertainty of the various thermal expansion models used namely: Empirical, Finite Element Method (FEM) models and FEM metamodels. Results have shown that the suggested methodology can accurately predict the uncertainty of the thermal deformation predictions made and thus compensations. The analysis of the results further showed how using this method a ‘digital twin’ of the engineering structure can be calibrated with known uncertainty of the thermal deformation behaviour predictions in the micrometric range. Namely, the Empirical, FEM and FEM metamodels combined standard uncertainties ( uc(y) ) of prediction were validated to be of maximum: 8.7â€ŻÎŒm, 11.28â€ŻÎŒm and 12.24â€ŻÎŒm for the studied magnet assemblies

    Performance of LHC Main Dipoles for Beam Operation

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    At present about 90% of the main dipoles for the LHC have been manufactured and one of the three cold mass assemblers has already completed the production. 85% of the 1232 dipoles needed for the tunnel have been tested and accepted. In this paper we mainly deal with the performance results: the quench behaviour, the magnetic field quality, the electrical integrity quality and the geometry features will be summarized

    Clinical validation of full HR-HPV genotyping HPV Selfy assay according to the international guidelines for HPV test requirements for cervical cancer screening on clinician-collected and self-collected samples

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    Background According to international guidelines, Human Papillomavirus (HPV) DNA tests represent a valid alternative to Pap Test for primary cervical cancer screening, provided that they guarantee balanced clinical sensitivity and specificity for cervical intraepithelial neoplasia grade 2 or more (CIN2+) lesions. The study aimed to assess whether HPV Selfy (Ulisse BioMed - Trieste, Italy), a full-genotyping HPV DNA test that detects and differentiates 14 high-risk HPV (HR-HPV) types, meets the criteria for primary cervical cancer screening described in the international guidelines, on clinician-collected as well as on self-collected samples. Methods For each participant woman, consecutively referring to Azienda Sanitaria Universitaria Giuliano Isontina (Trieste, Italy) and CRO-National Cancer Institute (Aviano, Italy) for the cervical cancer screening program, the following samples were tested: (a) a clinician-collected cervical specimen, analyzed with the reference test (Hybrid Capture (R) 2 test, HC2) and HPV Selfy; and (b) a self-collected vaginal sample, analyzed with HPV Selfy. Enrolled women were also asked to fulfill a questionnaire about self-sampling acceptability. As required by guidelines, a non-inferiority test was conducted to compare the clinical performance of the test under evaluation with its reference test. Results HPV Selfy clinical sensitivity and specificity resulted non-inferior to those of HC2. By analysis of a total of 889 cervical liquid-based cytology samples from a screening population, of which 98 were from women with CIN2+, HPV Selfy showed relative sensitivity and specificity for CIN2+ of 0.98 and 1.00 respectively (non-inferiority score test: P = 0.01747 and P = 0.00414, respectively); the test reached adequate intra- and inter-laboratory reproducibility. Moreover, we demonstrated that the performance of HPV Selfy on self-collected vaginal samples was non-inferior to the performance obtained on clinician-collected cervical specimen (0.92 relative sensitivity and 0.97 relative specificity). Finally, through HPV Selfy genotyping, we were able to describe HPV types prevalence in the study population. Conclusions HPV Selfy fulfills all the requirements of the international Meijer's guidelines and has been clinically validated for primary cervical cancer screening purposes. Moreover, HPV Selfy has also been validated for self-sampling according to VALHUDES guidelines. Therefore, at date, HPV Selfy is the only full-genotyping test validated both for screening purposes and for self-sampling. Trial registration ASUGI Trieste n. 16008/2018; CRO Aviano n.17149/201

    Ruinas, cĂ­rculos, construcciones

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    This article is organized around three groups of 'citations' from architectural forms, texts, images, which generate three options of imagination, representation and reading of space: ruins, circular constructions, and rhetoric (in particular figures of repetition). I discuss the story of Borges "Las ruinas circulares" and examples from Iain Sinclair, London orbital (2002), Gianni Biondillo and Michele Monina, Tangenziali. Due viandanti ai bordi della cittĂ  (2010), and NicolĂČ Bassetti, Sapo Matteucci, Sacro romano GRA (2013). The circularity generates a repetitive and disparate look allowing the observation of a complementary rhythm of destruction and construction characteristic of progress in the world
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