71 research outputs found
Interaction of gypsum and the rhizome of Anemarrhena asphodeloides plays an important role in anti-allergic effects of byakkokakeishito in mice
Exercise classification using CNN with image frames produced from time-series motion data
Exercise support systems for the elderly have been developed and some were equipped with a motion sensor to evaluate their exercise motion. Normally, it provides three-dimensional time-series data of over 20 joints. In this study, we propose to apply Convolutional Neural Network (CNN) methodology to the motion evaluation. The method converts the motion data of one exercise interval into one gray scale image. From simulation results, the CNN was possible to classify the images into specified motions
Production of unnatural glucosides of curcumin with drastically enhanced water solubility by cell suspension cultures of Catharanthus roseus
AbstractCatharanthus roseus cell suspension cultures converted exogenously supplied curcumin to a series of glucosides, none of which has been found in nature so far. The efficiency of glucosylation was dependent on culture stage of the cells and medium sucrose concentration. Methyl jasmonate and salicylic acid enhanced the glucoside formation only when they were added to the cultures prior to the addition of curcumin. The glucoside yield was 2.5 μmol/g fresh weight of the cells at an optimal culture condition. The water solubility of curcumin-4′,4″-O-β-D-digentiobioside was 0.65 mmol/ml, which was 20 million-fold higher than that of curcumin
Removal of accidentally ingested large foreign object via the anus after watchful waiting
One of the commonest complaints, for which a patient arrives in hospitals, is the presence of foreign body. It could be due to accidental ingestion or any other cause which leads to presences of a foreign body in the gastrointestinal tract. It is believed that foreign objects larger than 5–6 cm in size are unlikely to pass through the duodenum. Here, we describe a case wherein the patient accidentally swallowed a 7-cm-sized mouthguard that could not be removed by emergency upper gastrointestinal endoscopy but was subsequently removed via the anus after a period of watchful waiting
Effect of Soil Moisture Content on Growth, Crude Drug "Cho-to-ko" Yield and Oxindole Alkaloid Content of Uncaria rhynchophylla (B. LIVING SCIENCE)
Uncaria rhynchophylla was cultivated by using soil with various moisture contents (20,40,60,80 or 100% of the maximum moisture content retained by soil). Both growth and crude drug "Cho-to-ko" (dried stem with hooks of U. rhynchophylla) yield of the plant were in the following order : 60%> 80%> 40%> 100%> 20%, while oxindole alkaloid content of the stem was in the following order : 20%> 60%> 100%> 40%> 80%. It is concluded that moderately wet soil is suitable for cultivation of U. rhynchophylla, in spite of the description in a Chinese literature that sandy soil is good for cultivation of the plants
Seasonal Changes of Oxindole Alkaloid Contents in the Stem Segments of Uncaria rhynchophylla (B. LIVING SCIENCE)
The seasonal changes of oxindole alkaloid content in stem segments of Uncaria rhynchophylla were investigated between July 1986 and June 1987. The highest oxindole alkaloid content in the dried stem segments was observed in July 1986,and the content decreased until the next spring, when it started to increase again. In contrast, high biomass production was obtained in winter (November and December). The optimum season to prepare the crude drug from U. rhynchophylla is discussed in relation to oxindole alkaloid content and biomass yield
Characterization of Triterpene Saponin Glycyrrhizin Transport by Glycyrrhiza glabra
Glycyrrhizin (GL), a triterpene compound produced by Glycyrrhiza species, is a crucial pharmacologically active component of crude drugs. In contrast to the biosynthesis of GL in plants, little is known about GL transport and accumulation in plants. The transport mechanism of GL was characterized using cultured cells of Glycyrrhiza glabra. Cultured cells of G. glabra efficiently incorporated exogenously supplied GL. Proton pump inhibitors, such as probenecid and niflumic acid, as well as a protonophore (carbonylcyanide m-chlorophenylhydrazone), markedly inhibited GL uptake by cultured cells, whereas vanadate exhibited a moderate inhibition. Furthermore, GL transport by G. glabra tonoplast vesicles is dependent not on a H+-electrochemical gradient but MgATP and is markedly inhibited by vanadate. These results suggest that GL uptake by cultured cells is mediated by a H+-symporter in the plasma membrane and an ATP-binding cassette transporter, which has high specificity for the aglycone structure of GL on the tonoplast
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