317 research outputs found
Decoupling a Cooper-pair box to enhance the lifetime to 0.2 ms
We present a circuit QED experiment in which a separate transmission line is
used to address a quasi-lumped element superconducting microwave resonator
which is in turn coupled to an Al/AlO/Al Cooper-pair box (CPB) charge
qubit. In our measurements we find a strong correlation between the measured
lifetime of the CPB and the coupling between the qubit and the transmission
line. By monitoring perturbations of the resonator's 5.44 GHz resonant
frequency, we have measured the spectrum, lifetime (), Rabi, and Ramsey
oscillations of the CPB at the charge degeneracy point while the CPB was
detuned by up to 2.5 GHz . We find a maximum lifetime of the CPB was s for to 4.5 GHz. Our measured 's are consistent with
loss due to coupling to the transmission line, spurious microwave circuit
resonances, and a background decay rate on the order of
s of unknown origin, implying that the loss tangent in the AlO
junction barrier must be less than about at 4.5 GHz, about 4
orders of magnitude less than reported in larger area Al/AlO/Al tunnel
junctions
Quantum and thermal spin relaxation in diluted spin ice: Dy(2-x)MxTi2O7 (M = Lu, Y)
We have studied the low temperature a.c. magnetic susceptibility of the
diluted spin ice compound Dy(2-x)MxTi2O7, where the magnetic Dy ions on the
frustrated pyrochlore lattice have been replaced with non-magnetic ions, M = Y
or Lu. We examine a broad range of dilutions, 0 <= x <= 1.98, and we find that
the T ~ 16 K freezing is suppressed for low levels of dilution but re-emerges
for x > 0.4 and persists to x = 1.98. This behavior can be understood as a
non-monotonic dependence of the quantum spin relaxation time with dilution. The
results suggest that the observed spin freezing is fundamentally a single spin
process which is affected by the local environment, rather than the development
of spin-spin correlations as earlier data suggested.Comment: 26 pages, 9 figure
Quantum-Classical Reentrant Relaxation Crossover in Dy2Ti2O7 Spin-Ice
We have studied spin relaxation in the spin ice compound Dy2Ti2O7 through
measurements of the a.c. magnetic susceptibility. While the characteristic spin
relaxation time is thermally activated at high temperatures, it becomes almost
temperature independent below Tcross ~ 13 K, suggesting that quantum tunneling
dominates the relaxation process below that temperature. As the low-entropy
spin ice state develops below Tice ~ 4 K, the spin relaxation time increases
sharply with decreasing temperature, suggesting the emergence of a collective
degree of freedom for which thermal relaxation processes again become important
as the spins become highly correlated
Surface effects on nanowire transport: numerical investigation using the Boltzmann equation
A direct numerical solution of the steady-state Boltzmann equation in a
cylindrical geometry is reported. Finite-size effects are investigated in large
semiconducting nanowires using the relaxation-time approximation. A nanowire is
modelled as a combination of an interior with local transport parameters
identical to those in the bulk, and a finite surface region across whose width
the carrier density decays radially to zero. The roughness of the surface is
incorporated by using lower relaxation-times there than in the interior.
An argument supported by our numerical results challenges a commonly used
zero-width parametrization of the surface layer. In the non-degenerate limit,
appropriate for moderately doped semiconductors, a finite surface width model
does produce a positive longitudinal magneto-conductance, in agreement with
existing theory. However, the effect is seen to be quite small (a few per cent)
for realistic values of the wire parameters even at the highest practical
magnetic fields. Physical insights emerging from the results are discussed.Comment: 15 pages, 7 figure
Quantum Zeno stabilization in weak continuous measurement of two qubits
We have studied quantum coherent oscillations of two qubits under continuous
measurement by a symmetrically coupled mesoscopic detector. The analysis is
based on a Bayesian formalism that is applicable to individual quantum systems.
Measurement continuously collapses the two-qubit system to one of the
sub-spaces of the Bell basis. For a detector with linear response this
corresponds to measurement of the total spin of the qubits. In the other
extreme of purely quadratic response the operator \sigma_y^1 \sigma_y^2 +
\sigma_z^1 \sigma_z^2 is measured. In both cases, collapse naturally leads to
spontaneous entanglement which can be identified by measurement of the power
spectrum and/or the average current of the detector. Asymmetry between the two
qubits results in evolution between the different measurement subspaces.
However, when the qubits are even weakly coupled to the detector, a kind of
quantum Zeno effect cancels the gradual evolution and replaces it with rare,
abrupt switching events. We obtain the asymptotic switching rates for these
events and confirm them with numerical simulations. We show how such switching
affects the observable power spectrum on different time scales.Comment: 18 pages, 8 eps figures, reference adde
Thermal transport measurements of individual multiwalled nanotubes
The thermal conductivity and thermoelectric power of a single carbon nanotube
were measured using a microfabricated suspended device. The observed thermal
conductivity is more than 3000 W/K m at room temperature, which is two orders
of magnitude higher than the estimation from previous experiments that used
macroscopic mat samples. The temperature dependence of the thermal conductivity
of nanotubes exhibits a peak at 320 K due to the onset of Umklapp phonon
scattering. The measured thermoelectric power shows linear temperature
dependence with a value of 80 V/K at room temperature.Comment: 4 pages, figures include
Maximally-localized Wannier functions for entangled energy bands
We present a method for obtaining well-localized Wannier-like functions (WFs)
for energy bands that are attached to or mixed with other bands. The present
scheme removes the limitation of the usual maximally-localized WFs method (N.
Marzari and D. Vanderbilt, Phys. Rev. B 56, 12847 (1997)) that the bands of
interest should form an isolated group, separated by gaps from higher and lower
bands everywhere in the Brillouin zone. An energy window encompassing N bands
of interest is specified by the user, and the algorithm then proceeds to
disentangle these from the remaining bands inside the window by filtering out
an optimally connected N-dimensional subspace. This is achieved by minimizing a
functional that measures the subspace dispersion across the Brillouin zone. The
maximally-localized WFs for the optimal subspace are then obtained via the
algorithm of Marzari and Vanderbilt. The method, which functions as a
postprocessing step using the output of conventional electronic-structure
codes, is applied to the s and d bands of copper, and to the valence and
low-lying conduction bands of silicon. For the low-lying nearly-free-electron
bands of copper we find WFs which are centered at the tetrahedral interstitial
sites, suggesting an alternative tight-binding parametrization.Comment: 13 pages, with 9 postscript figures embedded. Uses REVTEX and epsf
macro
Bacteraemia among severely malnourished children infected and uninfected with the human immunodeficiency virus-1 in Kampala, Uganda
BACKGROUND: To establish the magnitude of bacteraemia in severely malnourished children, and describe the types of bacteria and antimicrobial sensitivity by HIV status. METHOD: Isolates were recovered from 76 blood specimens. Antibiotic susceptibility tests were performed using commercial antibiotic disks and demographic and clinical findings were recorded. RESULTS: Of the 450 children 63% were male; median age 17.0 months (inter quartile range, IQR 12–24) and 57% had oedema. 151 (36.7 %) of 411 tested HIV-positive; 76 (17.1%) of 445 blood specimens grew bacterial isolates; 58% were Gram negative – S. typhimurium (27.6%) and S. enteriditis (11.8%). Staph. aureus (26.3%) and Strep. pneumoniae (13.2%) were the main Gram positive organisms. There was no difference in the risk of bacteraemia by HIV status, age < 24 months, male sex, or oedema, except for oral thrush (OR 2.3 CI 1.0–5.1) and hypoalbuminaemia (OR 3.5 CI 1.0–12.1). Isolates from severely immuno-suppressed children (CD4% <15%) were more likely to grow Salmonella enteriditis (OR 5.4; CI 1.6 – 17.4). The isolates were susceptible (≥ 80%) to ciprofloxacin, ceftriaxone and gentamicin; with low susceptibility to chlorampenicol, ampicillin (< 50%) and co-trimoxazole (<25%). Suspicion of bacteraemia had 95.9% sensitivity and 99.2% specificity. Among bacteraemic children, mortality was higher (43.5% vs 20.5%) in the HIV-positive; OR 3.0 (95%CI 1.0, 8.6). CONCLUSION: Bacteraemia affects 1 in every 6 severely malnourished children and carries high mortality especially among the HIV-positive. Given the high level of resistance to common antibiotics, there is need for clinical trials to determine the best combinations of antibiotics for management of bacteraemia in severely malnourished children
Potent Innate Immune Response to Pathogenic Leptospira in Human Whole Blood
Background: Leptospirosis is caused by pathogenic spirochetes of the genus Leptospira. The bacteria enter the human body via abraded skin or mucous membranes and may disseminate throughout. In general the clinical picture is mild but some patients develop rapidly progressive, severe disease with a high case fatality rate. Not much is known about the innate immune response to leptospires during haematogenous dissemination. Previous work showed that a human THP-1 cell line recognized heat-killed leptospires and leptospiral LPS through TLR2 instead of TLR4. The LPS of virulent leptospires displayed a lower potency to trigger TNF production by THP-1 cells compared to LPS of non-virulent leptospires. Methodology/Principal Findings: We investigated the host response and killing of virulent and non-virulent Leptospira of different serovars by human THP-1 cells, human PBMC's and human whole blood. Virulence of each leptospiral strain was tested in a well accepted standard guinea pig model. Virulent leptospires displayed complement resistance in human serum and whole blood while in-vitro attenuated non-virulent leptospires were rapidly killed in a complement dependent manner. In vitro stimulation of THP-1 and PBMC's with heat-killed and living leptospires showed differential serovar and cell type dependence of cytokine induction. However, at low, physiological, leptospiral dose, living virulent complement resistant strains were consistently more potent in whole blood stimulations than the corresponding non-virulent complement sensitive strains. At higher dose living virulent and non-virulent leptospires were equipotent in whole blood. Inhibition of different TLRs indicated that both TLR2 and TLR4 as well as TLR5 play a role in the whole blood cytokine response to living leptospires. Conclusions/Significance: Thus, in a minimally altered system as human whole blood, highly virulent Leptospira are potent inducers of the cytokine response
Quantum Computing
Quantum mechanics---the theory describing the fundamental workings of
nature---is famously counterintuitive: it predicts that a particle can be in
two places at the same time, and that two remote particles can be inextricably
and instantaneously linked. These predictions have been the topic of intense
metaphysical debate ever since the theory's inception early last century.
However, supreme predictive power combined with direct experimental observation
of some of these unusual phenomena leave little doubt as to its fundamental
correctness. In fact, without quantum mechanics we could not explain the
workings of a laser, nor indeed how a fridge magnet operates. Over the last
several decades quantum information science has emerged to seek answers to the
question: can we gain some advantage by storing, transmitting and processing
information encoded in systems that exhibit these unique quantum properties?
Today it is understood that the answer is yes. Many research groups around the
world are working towards one of the most ambitious goals humankind has ever
embarked upon: a quantum computer that promises to exponentially improve
computational power for particular tasks. A number of physical systems,
spanning much of modern physics, are being developed for this task---ranging
from single particles of light to superconducting circuits---and it is not yet
clear which, if any, will ultimately prove successful. Here we describe the
latest developments for each of the leading approaches and explain what the
major challenges are for the future.Comment: 26 pages, 7 figures, 291 references. Early draft of Nature 464, 45-53
(4 March 2010). Published version is more up-to-date and has several
corrections, but is half the length with far fewer reference
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