Japanese Branch Report- 2008

On Saturday 29 November 2008, the twelfth Annual Convention of the George Eliot Fellowship of Japan was held at Kinki University. The morning session began with an opening remark by Yosie Abe (Shoin University), followed by a welcome address by Itsuyo Shimizu (Kinki University). In the morning, we had three papers presented. The first two papers were introduced and commented upon by Chizuko Watari (Kanasai Gaidai University), and the third by Keiji Yata (Tokyo Kasei University). The first paper was \u27Maggie\u27s Struggle in The Mill on the Floss\u27 by Muneaki Shinoda (the Graduate School of Osaka City University). He drew attention to the similarity between Maggie and Antigone, referring to Judith Butler\u27s interpretation of Antigone, and discussed the question of female education and Maggie. He compared Maggie as the defender of moral law with Tom as the defender of social law The second paper was \u27The Tragic Love of Fedalma and Silva - The Spanish Gypsy from the Ethnic Point of View\u27 by Nanae Hama (the Graduate School of Fukuoka Women\u27s University). She pointed out the correspondence between 15th century Spain and 19th century Britain as periods of ethnic controversy, and argued that the wedding ceremony of the lovers before their final separation suggests Eliot\u27s fervent desire for the coexistence of the two different nations, which was difficult to realize in her time. The third paper was \u27Reading Middlemarch as Gothic Romance\u27 by Hiromi Takei (The Jikei University School of Medicine). She examined several Gothic elements in Middlemarch Mr. Casaubon and Lowick Manor as a good example of identification of a Gothic house with its owner; Dorothea, a parentless heroine in fetters; Ladislaw, a free-spirited hero and rescuer who is represented in terms of light. She discussed how Eliot made use of the Gothic tradition in her own way, and suggested that Eliot\u27s desire to analyze psychology necessitated a minute description of characters as well as their houses. The afternoon session began with an address by Yoshitsugu Uchida, the President of the George Eliot Fellowship of Japan, which was followed by a welcome address by Professor Nobuyuki Inomo, the Dean of the School of Literature, Arts and Cultural Studies of Kinki University. After the addresses, the general meeting was presided over by Yoshie Abe. The meeting\u27s agenda included financial reports and publications of the Fellowship, one of which is The Bibliography of Works on George Eliot Published in Japan

Effect of Edge-Preserving Adaptive Image Filter on Low-Contrast Detectability in CT Systems: Application of ROC Analysis

Objective. For the multislice CT (MSCT) systems with a larger number of detector rows, it is essential to employ dose-reduction techniques. As reported in previous studies, edge-preserving adaptive image filters, which selectively eliminate only the noise elements that are increased when the radiation dose is reduced without affecting the sharpness of images, have been developed. In the present study, we employed receiver operating characteristic (ROC) analysis to assess the effects of the quantum denoising system (QDS), which is an edge-preserving adaptive filter that we have developed, on low-contrast resolution, and to evaluate to what degree the radiation dose can be reduced while maintaining acceptable low-contrast resolution. Materials and Methods. The low-contrast phantoms (Catphan 412) were scanned at various tube current settings, and ROC analysis was then performed for the groups of images obtained with/without the use of QDS at each tube current to determine whether or not a target could be identified. The tube current settings for which the area under the ROC curve (Az value) was approximately 0.7 were determined for both groups of images with/without the use of QDS. Then, the radiation dose reduction ratio when QDS was used was calculated by converting the determined tube current to the radiation dose. Results. The use of the QDS edge-preserving adaptive image filter allowed the radiation dose to be reduced by up to 38%. Conclusion. The QDS was found to be useful for reducing the radiation dose without affecting the low-contrast resolution in MSCT studies

Adaptation with the to high altitude in sherpas: Association insertion/deletion polymorphism in the angiotensin-converting enzyme gene

ArticleWILDERNESS & ENVIRONMENTAL MEDICINE. 19(1): 22-29 (2008)journal articl

Search for Λ6^6_\LambdaH hypernucleus by the 6^6Li(π−,K+)(\pi^-,K^+) reaction at pπ−p_{\pi^-} = 1.2 GeV/cc

We have carried out an experiment to search for a neutron-rich hypernucleus, $^6_{\Lambda}$H, by the $^6$Li($\pi^-,K^+$) reaction at $p_{\pi^-}$ =1.2 GeV/$c$. The obtained missing mass spectrum with an estimated energy resolution of 3.2 MeV (FWHM) showed no peak structure corresponding to the $^6_{\Lambda}$H hypernucleus neither below nor above the $^4_{\Lambda}$H$+2n$ particle decay threshold. An upper limit of the production cross section for the bound $^6_{\Lambda}$H hypernucleus was estimated to be 1.2 nb/sr at 90% confidence level.Comment: 6 pages, 5 figures, published versio

SAHG, a comprehensive database of predicted structures of all human proteins

Most proteins from higher organisms are known to be multi-domain proteins and contain substantial numbers of intrinsically disordered (ID) regions. To analyse such protein sequences, those from human for instance, we developed a special protein-structure-prediction pipeline and accumulated the products in the Structure Atlas of Human Genome (SAHG) database at http://bird.cbrc.jp/sahg. With the pipeline, human proteins were examined by local alignment methods (BLAST, PSI-BLAST and Smith–Waterman profile–profile alignment), global–local alignment methods (FORTE) and prediction tools for ID regions (POODLE-S) and homology modeling (MODELLER). Conformational changes of protein models upon ligand-binding were predicted by simultaneous modeling using templates of apo and holo forms. When there were no suitable templates for holo forms and the apo models were accurate, we prepared holo models using prediction methods for ligand-binding (eF-seek) and conformational change (the elastic network model and the linear response theory). Models are displayed as animated images. As of July 2010, SAHG contains 42 581 protein-domain models in approximately 24 900 unique human protein sequences from the RefSeq database. Annotation of models with functional information and links to other databases such as EzCatDB, InterPro or HPRD are also provided to facilitate understanding the protein structure-function relationships

Gamma-Ray Spectroscopy in Lambda Hypernuclei

The present status of hypernuclear gamma-ray spectroscopy with Hyperball is summarized. We observed two gamma transitions of 16-Lambda-O(1- -> 1-,0-) and obtained the strength of the Lambda-N tensor force. In 10B(K-,pi- gamma) data, we did not observe the spin-flip M1 transition of 10-Lambda-B(2- -> 1-), but gamma rays from hyperfragments such as 7-Lambda-Li(7/2+ -> 5/2+) and 9-Lambda-Be(3/2+ ->1/2+) were observed. In 11B(pi+,K+ gamma) data, we observed six gamma transitions of 11_Lambda-B. We also attempted an inclusive gamma-ray measurement with stopped K- beam.Comment: 10 pages, 9 figures, 8th International Conference on Hypernuclear and Strange Particle Physics (HYP2003), Newport News, Virginia, 14-18 Oct 2003, to appear in Nuclear Physics