Abdominal Tumor Characterization and Recognition Using Superior-Order Cooccurrence Matrices, Based on Ultrasound Images

The noninvasive diagnosis of the malignant tumors is an important issue in research nowadays. Our purpose is to elaborate computerized, texture-based methods for performing computer-aided characterization and automatic diagnosis of these tumors, using only the information from ultrasound images. In this paper, we considered some of the most frequent abdominal malignant tumors: the hepatocellular carcinoma and the colonic tumors. We compared these structures with the benign tumors and with other visually similar diseases. Besides the textural features that proved in our previous research to be useful in the characterization and recognition of the malignant tumors, we improved our method by using the grey level cooccurrence matrix and the edge orientation cooccurrence matrix of superior order. As resulted from our experiments, the new textural features increased the malignant tumor classification performance, also revealing visual and physical properties of these structures that emphasized the complex, chaotic structure of the corresponding tissue

Deep Learning Techniques for Liver Tumor Recognition in Ultrasound Images

Cancer is one of the most severe diseases nowadays. Thus, tumor detection in a non-invasive and accurate manner is a challenging subject. Among these tumors, liver cancer is one of the most dangerous, being very common. Hepatocellular Carcinoma (HCC) is the most frequent malignant liver tumor. The golden standard for diagnosing HCC is mainly the biopsy, however invasive and risky, leading to infections, respectively to the spreading of the tumor through the body. We conceive computerized techniques for abdominal tumor recognition within medical images. Formerly, traditional, texture-based methods were involved for this purpose. Both classical texture analysis methods, as well as advanced, original texture analysis techniques, based on superior order statistics, were involved. The superior order Gray Level Cooccurrence Matrix (GLCM), as well as the Textural Microstructure Cooccurrence Matrices (TMCM) were employed and assessed. Recently, deep learning techniques based on Convolutional Neural Networks (CNN), their fusions with the conventional techniques, as well as their combinations among themselves, were assessed in the approached field. We present the most relevant aspects of this study in the current paper

Isolated Microorganisms for Bioconversion of Biodiesel-Derived Glycerol Into 1,3-Propanediol

During biodiesel production, massive amounts of raw glycerol are created generating an environmental issue and the same time an increase of biodiesel production cost at the same time. This raw glycerol could be converted by specific strains into value-added products, like 1,3-propanediol (1,3-PD), an important monomer used in the synthesis of biodegradable polyesters.The present work is based on recent scientific articles and experimental studies on the targeted topic, namely on the use of bacterial strains for bioconversion of biodiesel-derived glycerol into valuable products, like 1,3-PD. Concentrations, yields and productivity of 1,3-PD are presented for various bacterial strains. Important results as respects the microbial bioconversion of biodiesel-derived glycerol into 1,3-PD were registered for strains like Klebsiella pneumoniae, Citrobacter freundii, Escherichia coli and Lactobacillus diolivorans.From this study can be concluded that waste glycerol may be used as a nutrient source for microbial development and the production of 1,3-propanediol with high concentrations and yields

Hepatocellular Carcinoma Recognition from Ultrasound Images Using Combinations of Conventional and Deep Learning Techniques

Hepatocellular Carcinoma (HCC) is the most frequent malignant liver tumor and the third cause of cancer-related deaths worldwide. For many years, the golden standard for HCC diagnosis has been the needle biopsy, which is invasive and carries risks. Computerized methods are due to achieve a noninvasive, accurate HCC detection process based on medical images. We developed image analysis and recognition methods to perform automatic and computer-aided diagnosis of HCC. Conventional approaches that combined advanced texture analysis, mainly based on Generalized Co-occurrence Matrices (GCM) with traditional classifiers, as well as deep learning approaches based on Convolutional Neural Networks (CNN) and Stacked Denoising Autoencoders (SAE), were involved in our research. The best accuracy of 91% was achieved for B-mode ultrasound images through CNN by our research group. In this work, we combined the classical approaches with CNN techniques, within B-mode ultrasound images. The combination was performed at the classifier level. The CNN features obtained at the output of various convolution layers were combined with powerful textural features, then supervised classifiers were employed. The experiments were conducted on two datasets, acquired with different ultrasound machines. The best performance, above 98%, overpassed our previous results, as well as representative state-of-the-art results

Iterative Methods for Obtaining Energy-Minimizing Parametric Snakes with Applications to Medical Imaging

After a brief survey on the parametric deformable models, we develop an iterative method based on the finite difference schemes in order to obtain energy-minimizing snakes. We estimate the approximation error, the residue, and the truncature error related to the corresponding algorithm, then we discuss its convergence, consistency, and stability. Some aspects regarding the prosthetic sugical methods that implement the above numerical methods are also pointed out

The role of the complex textural microstructure co-occurrence matrices, based on Laws’ features, in the characterization and recognition of some pathological structures, from ultrasound images

The non-invasive diagnosis, based on ultrasound images, is a challenge in nowadays research. We develop computerized, texture-based methods, for automatic and computer assisted diagnosis, using the information obtained from ultrasound images. In this work, we defined the co-occurrence matrix of complex textural microstructures determined by using the Laws’ convolution filters and we experimented it in order to perform the characterization and recognition of some important anatomical and pathological structures, within ultrasound images. These structures were the colorectal tumors and the gingival sulcus, the properties of the latter being important concerning the diagnosis and monitoring of the periodontal disease. We determined the textural model of these structures, using the classical and the newly defined textural features. For the automatic recognition, we used powerful classifiers, such as the Multilayer Perceptron, the Support-Vector Machines, decision-trees based classifiers such as Random Forest and C4.5, respectively AdaBoost in combination with the C4.5 algorithm

Concept Mapping, an Effective Tool for Long-Term Memorization of Anatomy—A Quasi-Experimental Research Carried out among 1st Year General Medicine Students

This study is part of a doctoral thesis conducted at the Faculty of Psychology of Babes-Bolyai University in collaboration with the University of Medicine, both from Cluj-Napoca, Romania. The starting point of the study was based on the eternal question of the medical student—“How should I learn to manage to retain so much information?” This is how learning through conceptual maps and learning by understanding has been achieved. In the study, a number of 505 students from the Faculty of General Medicine were randomly selected and divided into groups, to observe changes in the grades they obtained when learning anatomy with the concept mapping method vs. traditional methods. Six months later, a retest was carried out to test long-term memory. The results were always in favor of the experimental group and were statistically significant (with one exception), most notably for the 6-month retesting. It was also observed that the language of teaching, different or the same as the first language, explains that exception, at least partially. Other results were taken into account, such as the distribution of bad and good grades in the two groups. Other parameters that influenced the obtained results and which explain some contradictory results in the literature are discussed. In conclusion, the use of conceptual maps is useful for most students, both for short and long-term memory