Gas leak detector is simple and inexpensive

Pressure sensor monitors small gas leaks in piping and pressure vessels. A combination of a paper ribbon and adhesive plastic tape is used to cover the area to be monitored and the pressure sensor is placed over a hole in the tape and paper

Optical inspection tool for interior surfaces of fluid lines

Specialized tool enables visual inspection of interior bore surfaces of pipe lines having sharp bends and blind runs. Adjustable, hinged optical head permits viewing of bore surfaces at angles from 0 deg to 115 deg to the principal axis of the sight tube

Rotary-knife stripper facilitates removal of X-ray film from pack

Rotary-knife stripper facilitates removal of X ray film from the daylight pack paper sleeve. The new stripper is rectangular, approximately 4 inches wide, 5 inches high, and 7 inches long

Computer program determines thermal environment and temperature history of lunar orbiting space vehicles

Program computes the thermal environment of a spacecraft in a lunar orbit. The quantities determined include the incident flux /solar and lunar emitted radiation/, total radiation absorbed by a surface, and the resulting surface temperature as a function of time and orbital position

Bacterial Quality of Private Water Wells in Clark County, Arkansas

Most private water wells in Clark County appeared to be contaminated by bacteria, apparently entering the wells from surface water seepage. Eighteen to 24% of the wells investigated were positive for fecal contamination. Deeper wells were less often contaminated. More than one-half of the wells sampled exceeded recommended limits of inorganic chemicals for safe potable water. High concentrations of iron and manganese were most common, exceeding recommended limits in more than 40% of the well

Ultrasonic hand tool allows convenient scanning of spot welds

Small, portable, electrically powered hand tool, coupled with auxiliary ultrasonic equipment, allows convenient scanning of spot welds for discontinuities

A study of possible sea state information in the sample and hold gate statistics for the GEOS-3 satellite altimeter

The statistical variations in the sample gate outputs of the GEOS-3 satellite altimeter were studied for possible sea state information. After examination of a large number of statistical characteristics of the altimeter waveforms, it was found that the best sea predictor for H-1/3 in the range of 0 to 3 meters was the 75th percentile of sample and hold gate number 11

IL-17 can be protective or deleterious in murine pneumococcal pneumonia

Streptococcus pneumoniae is the major bacterial cause of community-acquired pneumonia, and the leading agent of childhood pneumonia deaths worldwide. Nasal colonization is an essential step prior to infection. The cytokine IL-17 protects against such colonization and vaccines that enhance IL-17 responses to pneumococcal colonization are being developed. The role of IL-17 in host defence against pneumonia is not known. To address this issue, we have utilized a murine model of pneumococcal pneumonia in which the gene for the IL-17 cytokine family receptor, Il17ra, has been inactivated. Using this model, we show that IL-17 produced predominantly from γδ T cells protects mice against death from the invasive TIGR4 strain (serotype 4) which expresses a relatively thin capsule. However, in pneumonia produced by two heavily encapsulated strains with low invasive potential (serotypes 3 and 6B), IL-17 significantly enhanced mortality. Neutrophil uptake and killing of the serotype 3 strain was significantly impaired compared to the serotype 4 strain and depletion of neutrophils with antibody enhanced survival of mice infected with the highly encapsulated SRL1 strain. These data strongly suggest that IL-17 mediated neutrophil recruitment to the lungs clears infection from the invasive TIGR4 strain but that lung neutrophils exacerbate disease caused by the highly encapsulated pneumococcal strains. Thus, whilst augmenting IL-17 immune responses against pneumococci may decrease nasal colonization, this may worsen outcome during pneumonia caused by some strains