A study to assess the therapeutic role of GM-CSF (EMGRAST -M) on augmentation of total leucocyte count and total platelet count in cancer patients after chemotherapy

Background: The aim of the present study was to assess the therapeutic role of GM-CSF (EMGRAST -M) on augmentation of total leucocyte count and total platelet count in cancer patients after chemotherapy.Methods: The total leucocyte count (TLC) and total platelet count (TPC) of thirty patients on chemotherapy were obtained before and after the administration of GM-CSF. The results were analysed retrospectively for the effect of GM-CSF on these parameters. Statistical analysis was done, and graphs were made by Libre office calc and Student’s T Test was used for comparison of data.Results: The study showed that EMGRAST-M had an impressive effect on both the platelet count and the leucocyte count.Conclusions: GM-CSF has a great therapeutic role in the enhancement of platelet count and leucocyte count in patients of cancer chemotherapy

Aceclofenac induced morbilliform eruptions: a case report

Maculopapular or morbilliform eruptions may be the most common of all cutaneous drug reactions. Antimicrobials, NSAIDS, barbiturates, anticonvulsants, oral hypoglycemics etc. have been commonly implicated in these adverse reactions (ADR). Here, authors are presenting a case of a 38-year-old female with morbilliform eruptions due to aceclofenac for the treatment of joint pain. The patient was treated with antihistaminics, steroids, antimicrobials and local application of GV paint. She was discharged after eleven days with good recovery

The use of ATC/DDD WHO 2016 and Prescription audit study in the Dermatology OPD of a tertiary care hospital in Jharkhand

Background: To study the prescribing patterns, rationale of drug usage and use of anatomical, therapeutic, chemical (ATC) and defined daily dosage (DDD) classification for the monitoring of drug utilization in the dermatology department of a tertiary care hospital.Methods: A retrospective, observational study was conducted in out-patients department of dermatology at RIMS, Ranchi over a period of two months. Rationale of drug usage was assessed by analysing the prescriptions. Defined daily dosage/1000 patients/day of the commonly used medications was compared to the defined daily dosage by World Health Organization in 2016. Data was analysed by statistical tools. Most of the results were expressed in percentages.Results: The prescriptions were rational in most of the cases. Emphasis was more towards the branded drugs. Polypharmacy was evident in many of the prescriptions. The number of DDD/1000 patients/day in cases of antifungals was more than the WHO DDD and less than the WHO DDD in case of antihistaminics.Conclusions: The number of drugs per prescription must be rationalized so as to avoid polypharmacy. The drugs should be prescribed by their generic names also along with the brand names. Generic medicines should be available in the hospital pharmacy so that a more cost-effective treatment can be assured. CMEs and stewardship programs for health care professionals regarding rational drug usage should be organized.

Aceclofenac induced morbilliform eruptions: a case report

Maculopapular or morbilliform eruptions may be the most common of all cutaneous drug reactions. Antimicrobials, NSAIDS, barbiturates, anticonvulsants, oral hypoglycemics etc. have been commonly implicated in these adverse reactions (ADR). Here, authors are presenting a case of a 38-year-old female with morbilliform eruptions due to aceclofenac for the treatment of joint pain. The patient was treated with antihistaminics, steroids, antimicrobials and local application of GV paint. She was discharged after eleven days with good recovery

A Survey on Citizens Broadband Radio Service (CBRS)

To leverage the existing spectrum and mitigate the global spectrum dearth, the Federal Communications Commission of the United States has recently opened the Citizens Broadband Radio Service (CBRS) spectrum, spanning 3550–3700 MHz, for commercial cognitive operations. The CBRS has a three-tier hierarchical architecture, wherein the incumbents, including military radars, occupy the topmost tier. The priority access licenses (PAL) and general authorized access (GAA) are second and third tier, respectively, facilitating licensed and unlicensed access to the spectrum. This combination of licensed and unlicensed access to the spectrum in a three-tier model has opened novel research directions in optimal spectrum sharing as well as privacy preservation, and hence, several schemes have been proposed for the same. This article provides a detailed survey of the existing literature on the CBRS. We provide an overview of the CBRS ecosystem and discuss the regulation and standardization process and industrial developments on the CBRS. The existing schemes for optimal spectrum sharing and resource allocation in CBRS are discussed in detail. Further, an in-depth study of the existing literature on the privacy of incumbents, PAL devices, and GAA devices in CBRS is presented. Finally, we discuss the open issues in CBRS, which demand more attention and effort