Alternative routes to good jobs in the service economy: Employment restructuring and human resource management in incumbent telecommunications firms

This is a practitioner report detailing findings from a three-year study on organizational restructuring and employment outcomes at 10 incumbent telecommunications firms, supported by the Economic and Social Research Council. It presents background on markets, ownership, and institutions in the case study firms and countries, and compares restructuring policies in three areas: downsizing and employment adjustment; diversifying employment contracts; and work organization and human resource Management. The report concludes with policy recommendations, based on findings from the study.ESRC Grant RES-061-25-044

Institutions and Inequality in Liberalizing Markets: Explaining Different Trajectories of Institutional Change in Social Europe

Economic and Social Research Council [grant number RES-061-25-0444]

Union campaigns to organize across production networks in the European telecommunications industry: lessons from the UK, Italy, Sweden and Poland

Freely available on the publisher's website: https://www.etui.org/Publications2/Books/The-outsourcing-challenge-organizing-workers-across-fragmented-production-networkshttps://www.etui.org/Publications2/Books/The-outsourcing-challenge-organizing-workers-across-fragmented-production-network

Anger, anxiety and corruption perceptions: Evidence from France

British Academy grant SG-101785

Crystal, Solution and In silico Structural Studies of Dihydrodipicolinate Synthase from the Common Grapevine

Dihydrodipicolinate synthase (DHDPS) catalyzes the rate limiting step in lysine biosynthesis in bacteria and plants. The structure of DHDPS has been determined from several bacterial species and shown in most cases to form a homotetramer or dimer of dimers. However, only one plant DHDPS structure has been determined to date from the wild tobacco species, Nicotiana sylvestris (Blickling et al. (1997) J. Mol. Biol. 274, 608–621). Whilst N. sylvestris DHDPS also forms a homotetramer, the plant enzyme adopts a ‘back-to-back’ dimer of dimers compared to the ‘head-to-head’ architecture observed for bacterial DHDPS tetramers. This raises the question of whether the alternative quaternary architecture observed for N. sylvestris DHDPS is common to all plant DHDPS enzymes. Here, we describe the structure of DHDPS from the grapevine plant, Vitis vinifera, and show using analytical ultracentrifugation, small-angle X-ray scattering and X-ray crystallography that V. vinifera DHDPS forms a ‘back-to-back’ homotetramer, consistent with N. sylvestris DHDPS. This study is the first to demonstrate using both crystal and solution state measurements that DHDPS from the grapevine plant adopts an alternative tetrameric architecture to the bacterial form, which is important for optimizing protein dynamics as suggested by molecular dynamics simulations reported in this study

Honesty above all else? Expectations and perceptions of political conduct in three established democracies

The authors gratefully acknowledge financial support from the ESRC (grant number RES-000-22-3459) and British Academy (grant numbers SG-101785 and SG-52322). They would also like to thank two anonymous reviewers for their helpful comments and suggestions

Overproduction of l-Lysine from Methanol by Methylobacillus glycogenes Derivatives Carrying a Plasmid with a Mutated dapA Gene

The dapA gene, encoding dihydrodipicolinate synthase (DDPS) partially desensitized to inhibition by l-lysine, was cloned from an l-threonine- and l-lysine-coproducing mutant of the obligate methylotroph Methylobacillus glycogenes DHL122 by complementation of the nutritional requirement of an Escherichia coli dapA mutant. Introduction of the dapA gene into DHL122 and AL119, which is the parent of DHL122 and an l-threonine producing mutant, elevated the specific activity of DDPS 20-fold and l-lysine production 2- to 3-fold with concomitant reduction of l-threonine in test tube cultures. AL119 containing the dapA gene produced 8 g of l-lysine per liter in a 5-liter jar fermentor from methanol as a substrate. Analysis of the nucleotide sequence of the dapA gene shows that it encodes a peptide with an M(r) of 30,664 and that the encoded amino acid sequence is extensively homologous to those of other organisms. In order to study the mutation that occurred in DHL122, the dapA genes of the wild type and AL119 were cloned and sequenced. Comparison of the nucleotide sequences of the dapA genes revealed that the amino acid at residue 88 was F in DHL122 whereas it was L in the wild type and AL119, suggesting that this amino acid alteration that occurred in DHL122 caused the partial desensitization of DDPS to the inhibition by l-lysine. The similarity in the amino acid sequences of DDPS in M. glycogenes and other organisms suggests that the mutation of the dapA gene in DHL122 is located in the region concerned with interaction of the allosteric effector, l-lysine

Can multiple streams predict the territorial cohesion debate in the EU?

This article contributes to the debate over the fashionable but contested concept of ‘territorial cohesion’ in the European Union. Scholars have long recognised and traced discursive shifts in EU territorial development policies, but theoretical accounts of the drivers and parameters of such shifts are rare. This article applies the multiple streams model of agenda-setting to the territorial cohesion debate in order to explore how useful this model is in analysing and predicting the outcome of a debate. The article is structured according to the three ‘streams’ that are relevant to agenda-setting: problems, policies and politics. The analysis relies on the responses to the 2008 Green Paper on Territorial Cohesion in order to determine how politically feasible different policy solutions are. More recent developments such as the Territorial Agenda 2020 and the European Commission’s proposals for Cohesion Policy for 2014–2020 are then used to assess the predictive power of multiple streams. It is shown that the model successfully predicts the endurance of solidarity-based cohesion goals, the emergence of territorial capital as a key policy solution, and the rejection of geographical criteria for the allocation of EU Structural Funds. At the same time, the multiple streams model fails to predict the introduction of spatial planning tools into EU cohesion policy. This shows that explaining a substantial redefinition of existing policy terms requires some reference to key actors’ broader discursive strategies. The article concludes that the multiple streams model has some predictive and explanatory power; criticisms of the model as overly descriptive are exaggerated