Non-Gorenstein isolated singularities of graded countable Cohen-Macaulay type

In this paper we show a partial answer the a question of C. Huneke and G. Leuschke (2003): Let R be a standard graded Cohen-Macaulay ring of graded countable Cohen-Macaulay representation type, and assume that R has an isolated singularity. Is R then necessarily of graded finite Cohen-Macaulay representation type? In particular, this question has an affirmative answer for standard graded non-Gorenstein rings as well as for standard graded Gorenstein rings of minimal multiplicity. Along the way, we obtain a partial classification of graded Cohen-Macaulay rings of graded countable Cohen-Macaulay type.Comment: 15 Page

Practical approach on frail older patients attended for acute heart failure

Acute heart failure (AHF) is a multi-organ dysfunction syndrome. In addition to known cardiac dysfunction, non-cardiac comorbidity, frailty and disability are independent risk factors of mortality, morbidity, cognitive and functional decline, and risk of institutionalization. Frailty, a treatable and potential reversible syndrome very common in older patients with AHF, increases the risk of disability and other adverse health outcomes. This position paper highlights the need to identify frailty in order to improve prognosis, the risk-benefits of invasive diagnostic and therapeutic procedures, and the definition of older-person-centered and integrated care plans

The Current State of Knowledge of Hepatic Ischemia-Reperfusion Injury Based on Its Study in Experimental Models

The present review focuses on the numerous experimental models used to study the complexity of hepatic ischemia/reperfusion (I/R) injury. Although experimental models of hepatic I/R injury represent a compromise between the clinical reality and experimental simplification, the clinical transfer of experimental results is problematic because of anatomical and physiological differences and the inevitable simplification of experimental work. In this review, the strengths and limitations of the various models of hepatic I/R are discussed. Several strategies to protect the liver from I/R injury have been developed in animal models and, some of these, might find their way into clinical practice. We also attempt to highlight the fact that the mechanisms responsible for hepatic I/R injury depend on the experimental model used, and therefore the therapeutic strategies also differ according to the model used. Thus, the choice of model must therefore be adapted to the clinical question being answered

Estudio de los componentes quinónicos de Salvia Verbenaca L.

The root of Salvia verbenaca L. present phenantraquinonic compounds, whose quantity and type is dependent to the ecology of soil where the plant grows. By mean s of UV-Vis., IR, H1-NMR and C13-NMR spectroscopy technics, the presence of methoxy and isopropyl groups, double bounds between carbons and aroma tic hydrogens was shown in the principal constituent (0,02% of richness).La raíz de Salvia verbenaca L. posee componentes fenantraquinónicos, cuya entidad y tipo varía con la ecología del terreno en donde se desarrolla el vegetal. Por técnicas de espectroscopía UV-Visible, IR, H1-RMN Y C13-RMN, se ha determinado en el componente mayoritario (riqueza de un 0,02%) la presencia en la estructura fenantraquinónica de grupos metoxilo, isopropilo, carbonos unidos por doble enlace e hidrógenos aromáticos

Estudio de los componentes quinónicos de Salvia Verbenaca L.

La raíz de Salvia verbenaca L. posee componentes fenantraquinónicos, cuya entidad y tipo varía con la ecología del terreno en donde se desarrolla el vegetal. Por técnicas de espectroscopía UV-Visible, IR, H1-RMN Y C13-RMN, se ha determinado en el componente mayoritario (riqueza de un 0,02%) la presencia en la estructura fenantraquinónica de grupos metoxilo, isopropilo, carbonos unidos por doble enlace e hidrógenos aromáticos.The root of Salvia verbenaca L. present phenantraquinonic compounds, whose quantity and type is dependent to the ecology of soil where the plant grows. By mean s of UV-Vis., IR, H1-NMR and C!3-NMR spectroscopy technics, the presence of methoxy and isopropyl groups, double bounds between carbons and aroma tic hydrogens was shown in the principal constituent (0,02% of richness)