48 research outputs found

    Compensating Competitors or Restoring Competition? EC Regulation of State Aid for Banks during the Crisis

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    We contrast the theory underpinning state aid for failing banks with that for failing firms in the real sector, and find that this should justify a different treatment for banks under Article 107. For example, there is little justification for measures to compensate rivals when the bank has been saved for reasons of systemic stability. We find that the formal guidance on bank restructuring aid takes insufficient notice of this. In four detailed case studies, we also find a number of inconsistencies with respect to size of subsidy, sustainability of divestitures or treatment of mergers. We conclude that while the Commission provided a useful constraint in the midst of a crisis of unprecedented scale and complexity, its approach could have been improved by focusing more closely on the fundamental justification of state aid in each case (i.e. the counterfactual)

    A Genetic Screen for Genes Involved in the FGF Signalling Pathway in Drosophila melanogaster

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    The FGF signal is important for cell survival, proliferation, differentiation and migration. It is not clear how the FGF signalling cascade is regulated. In order to identify genes downstream of FGF signalling, a gain-of-function (GOF) screen was conducted using the Drosophila compound eye as a model system. The screen was based on the observation that expression of an activated form of the FGF receptor and Dof together in the Drosophilia eye ('GMR>λ-fgfr, dof'), produces a rough eye phenotype, whereas expressing either alone has no effect. This implies that at least some of the components in the signalling cascade are present during Drosophila eye development. When one copy of raf, rhoA or rhoGEF was mutated, the rough eye phenotype of 'GMR>λ-fgfr, dof' flies was enhanced. In the screen, 'GMR>λ-fgfr, dof' flies were crossed to the EP collection and the progeny were screened for the modification of the rough eye phenotype. In total, 24 suppressors and 26 enhancers were obtained, which may affect 38 annotated genes. 8 lines did not have any interactions with other signalling pathways that I have tested, which are the PDGF and EGF signalling pathways, and pathways involving Cdc42 or Rac1. Nor were they found in any of the published GOF screens. In order to investigate the interaction of the candidates with the endogenous FGF signalling pathway, imprecise excisions of three candidates - EP719, EP3575 and EP863 - were generated and the mutant phenotypes were studied

    The quality and efficiency of public service delivery in the UK and China

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    Written evidence submitted to ‘The Future of Banking Commission’ relating to three of their areas of investigation: appropriate structure of the banking system, competition and provision of suitable products for consumers

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    Written evidence submitted to ‘The Future of Banking Commission’ relating to three of their areas of investigation: appropriate structure of the banking system, competition and provision of suitable products for consumer
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