149 research outputs found
Assessment as the basis of a secondary nomination in the language of journalism
Assessment in journalism – a phenomenon communicatively diverse. As a logical and philosophical category, it is a judgment based on the positive or negative attitude of the subject to the evaluated object based on its comparison with the figurative standard. It is closely related to cognition: by reflecting objects and phenomena of objective reality, one simultaneously recognizes the world and evaluates it from certain points of view. In terms of various needs, aspirations, goals. The realm of assessment is based on the opposition "good - bad", where "good" is one that fits the idealized model of the macro and micro worlds, and "bad" is the one that does not fit that model. The logical basis of the assessment is to compare the results of human activity with the qualitative socio-psychological categories of the sphere of human cognition and make judgments about the value of the object
Evolution of shell structure in neutron-rich calcium isotopes
We employ interactions from chiral effective field theory and compute the
binding energies and low-lying excitations of calcium isotopes with the
coupled-cluster method. Effects of three-nucleon forces are included
phenomenologically as in-medium two-nucleon interactions, and the coupling to
the particle continuum is taken into account using a Berggren basis. The
computed ground-state energies and the low-lying 2+ states for the isotopes
42,48,50,52Ca are in good agreement with data, and we predict the excitation
energy of the first 2+ state in 54Ca at 1.9 MeV, displaying only a weak
sub-shell closure. In the odd-mass nuclei 53,55,61Ca we find that the positive
parity states deviate strongly from the naive shell model.Comment: 5 pages, 4 figures; small correction of effective 3NF and slight
change of the corresponding parameters; updated figures and tables; main
results and conclusions unchange
Detection of Motor Changes in Huntington's Disease Using Dynamic Causal Modeling
Neurological Motor Disorder
Co-existing structures in 105Ru
New positive-parity states, having a band-like structure, were observed in
105Ru. The nucleus was produced in induced fission reaction and the prompt
gamma-rays, emitted from the fragments, were detected by the EUROBALL III
multi-detector array. The partial scheme of excited 105Ru levels is analyzed
within the Triaxial-Rotor-plus-Particle approach
Cross-sectional and longitudinal voxel-based grey matter asymmetries in Huntington's disease
Huntington's disease (HD) is a progressive neurodegenerative disorder that can be genetically confirmed with certainty decades before clinical onset. This allows the investigation of functional and structural changes in HD many years prior to disease onset, which may reveal important mechanistic insights into brain function, structure and organization in general. While regional atrophy is present at early stages of HD, it is still unclear if both hemispheres are equally affected by neurodegeneration and how the extent of asymmetry affects domain-specific functional decline. Here, we used whole-brain voxel-based analysis to investigate cross-sectional and longitudinal hemispheric asymmetries in grey matter (GM) volume in 56 manifest HD (mHD), 83 pre-manifest HD (preHD), and 80 healthy controls (HC). Furthermore, a regression analysis was used to assess the relationship between neuroanatomical asymmetries and decline in motor and cognitive measures across the disease spectrum. The cross-sectional analysis showed striatal leftward-biased GM atrophy in mHD, but not in preHD, relative to HC. Longitudinally, no net 36-month change in GM asymmetries was found in any of the groups. In the regression analysis, HD-related decline in quantitative-motor (Q-Motor) performance was linked to lower GM volume in the left superior parietal cortex. These findings suggest a stronger disease effect targeting the left hemisphere, especially in those with declining motor performance. This effect did not change over a period of three years and may indicate a compensatory role of the right hemisphere in line with recent functional imaging studies
Compensation in Preclinical Huntington's Disease: Evidence From the Track-On HD Study
BACKGROUND:
Cognitive and motor task performance in premanifest Huntington's disease (HD) gene-carriers is often within normal ranges prior to clinical diagnosis, despite loss of brain volume in regions involved in these tasks. This indicates ongoing compensation, with the brain maintaining function in the presence of neuronal loss. However, thus far, compensatory processes in HD have not been modeled explicitly. Using a new model, which incorporates individual variability related to structural change and behavior, we sought to identify functional correlates of compensation in premanifest-HD gene-carriers.
METHODS:
We investigated the modulatory effects of regional brain atrophy, indexed by structural measures of disease load, on the relationship between performance and brain activity (or connectivity) using task-based and resting-state functional MRI.
FINDINGS:
Consistent with compensation, as atrophy increased performance-related activity increased in the right parietal cortex during a working memory task. Similarly, increased functional coupling between the right dorsolateral prefrontal cortex and a left hemisphere network in the resting-state predicted better cognitive performance as atrophy increased. Such patterns were not detectable for the left hemisphere or for motor tasks.
INTERPRETATION:
Our findings provide evidence for active compensatory processes in premanifest-HD for cognitive demands and suggest a higher vulnerability of the left hemisphere to the effects of regional atrophy
Observation of Positive-Parity Bands in Pd and Pd: Enhanced -Softness
The neutron-rich nuclei Pd and Pd were produced as fission
fragments following the Si + Er reaction at 142 MeV. Using the
identification based on the coincidences with the complementary fission
fragments, the only positive-parity bands observed so far in Pd and
Pd emerged from this work. A band, built on top of the 5/2 ground
state exhibiting = 1 energy-level staggering, was observed in each
of these nuclei. Both nuclei of interest, Pd and Pd, are
suggested to lie in the transitional region of Pd isotopes of maximum
-softness. The ground states of both nuclei are predicted by TRS
calculations to be extremely -soft with shallow triaxial minima. The
first crossing in the new bands is proposed to be due to an alignment of
neutrons
Testing a longitudinal compensation model in premanifest Huntington's disease
Neurological Motor Disorder
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