Emotional Regulation, Level of Depression, Anxiety and Stress among Alcohol Abusers and Non-Abusers

The study was to examine the levels of depression anxiety and stress, as well as emotion regulation strategies among alcohol abusers and non-abusers. One hundred and fifty alcohol abusers who were admitted in department of psychiatry ward in hospital and one hundred and fifty normal people who were in general population were enrolled in the study. Depression, anxiety and stress scale (DASS-42) and emotional regulation questionnaires were used to assesses the depression, anxiety and stress reaction and emotional regulation of alcohol abusers and non-abusers. Alcohol abusers had higher level of depression, anxiety and stress reaction, as well as lower level of cognitive reappraisal and higher level of suppression compared with normal people. Cognitive reappraisal and suppression had significantly negative correlation with depression, anxiety and stress reaction in healthy people while they had no significantly correlation with depression, anxiety and stress reaction in abuser group. Further, both cognitive reappraisal and suppression significantly predicated depression, anxiety and stress reaction in healthy people while they did not predicate depression, anxiety and stress in alcohol abusers. Alcohol abusers had obvious depression, anxiety and stress reaction, as well as inappropriate copying strategies. Both cognitive reappraisal and suppression could predicate negative emotion and stress reaction in normal population but the emotional regulation failed to predicate negative emotion and stress reaction in alcohol abusers

Emotional Regulation, Level of Depression, Anxiety and Stress among Alcohol Abusers and Non-Abusers

The study was to examine the levels of depression anxiety and stress, as well as emotion regulation strategies among alcohol abusers and non-abusers. One hundred and fifty alcohol abusers who were admitted in department of psychiatry ward in hospital and one hundred and fifty normal people who were in general population were enrolled in the study. Depression, anxiety and stress scale (DASS-42) and emotional regulation questionnaires were used to assesses the depression, anxiety and stress reaction and emotional regulation of alcohol abusers and non-abusers. Alcohol abusers had higher level of depression, anxiety and stress reaction, as well as lower level of cognitive reappraisal and higher level of suppression compared with normal people. Cognitive reappraisal and suppression had significantly negative correlation with depression, anxiety and stress reaction in healthy people while they had no significantly correlation with depression, anxiety and stress reaction in abuser group. Further, both cognitive reappraisal and suppression significantly predicated depression, anxiety and stress reaction in healthy people while they did not predicate depression, anxiety and stress in alcohol abusers. Alcohol abusers had obvious depression, anxiety and stress reaction, as well as inappropriate copying strategies. Both cognitive reappraisal and suppression could predicate negative emotion and stress reaction in normal population but the emotional regulation failed to predicate negative emotion and stress reaction in alcohol abusers

A Survey of Deep Learning in Sports Applications: Perception, Comprehension, and Decision

Deep learning has the potential to revolutionize sports performance, with applications ranging from perception and comprehension to decision. This paper presents a comprehensive survey of deep learning in sports performance, focusing on three main aspects: algorithms, datasets and virtual environments, and challenges. Firstly, we discuss the hierarchical structure of deep learning algorithms in sports performance which includes perception, comprehension and decision while comparing their strengths and weaknesses. Secondly, we list widely used existing datasets in sports and highlight their characteristics and limitations. Finally, we summarize current challenges and point out future trends of deep learning in sports. Our survey provides valuable reference material for researchers interested in deep learning in sports applications

Formation of the synaptonemal complex in a gynogenetic allodiploid hybrid fish

Introduction: The correct pairing and separation of homologous chromosomes during meiosis is crucial to ensure both genetic stability and genetic diversity within species. In allodiploid organisms, synapsis often fails, leading to sterility. However, a gynogenetic allodiploid hybrid clone line (GDH), derived by crossing red crucian carp (Carassius auratus ♀) and common carp (Cyprinus carpio ♂), stably produces diploid eggs. Because the GDH line carries 100 chromosomes with 50 chromosomes from the red crucian carp (RCC; ♀, 2n = 2x = 100) and 50 chromosomes from the common carp (CC; C. carpio L., ♂, 2n = 2x = 100), it is interesting to study the mechanisms of homologous chromosome pairing during meiosis in GDH individuals.Methods: By using fluorescence in situ hybridization (FISH) with a probe specific to the red crucian carp to label homologous chromosomes, we identified the synaptonemal complex via immunofluorescence assay of synaptonemal complex protein 3 (SCP3).Results: FISH results indicated that, during early ovarian development, the GDH oogonium had two sets of chromosomes with only one set from Carassius auratus, leading to the failure formation of normal bivalents and the subsequently blocking of meiosis. This inhibition lasted at least 5 months. After this long period of inhibition, pairs of germ cells fused, doubling the chromosomes such that the oocyte contained two sets of chromosomes from each parent. After chromosome doubling at 10 months old, homologous chromosomes and the synaptonemal complex were identified.Discussion: Causally, meiosis proceeded normally and eventually formed diploid germ cells. These results further clarify the mechanisms by which meiosis proceeds in hybrids

Real-Time Endocytosis Imaging as a Rapid Assay of Ligand-GPCR Binding in Single Cells

http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000337000401693&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=8e1609b174ce4e31116a60747a720701BiophysicsSCI(E)CPCI-S(ISTP)0MEETING ABSTRACT2310A-310A10

Cross-species single-cell spatial transcriptomic atlases of the cerebellar cortex

The molecular and cellular organization of the primate cerebellum remains poorly characterized. We obtained single-cell spatial transcriptomic atlases of macaque, marmoset, and mouse cerebella and identified primate-specific cell subtypes, including Purkinje cells and molecular-layer interneurons, that show different expression of the glutamate ionotropic receptor Delta type subunit 2 (GRID2) gene. Distinct gene expression profiles were found in anterior, posterior, and vestibular regions in all species, whereas region-selective gene expression was predominantly observed in the granular layer of primates and in the Purkinje layer of mice. Gene expression gradients in the cerebellar cortex matched well with functional connectivity gradients revealed with awake functional magnetic resonance imaging, with more lobule-specific differences between primates and mice than between two primate species. These comprehensive atlases and comparative analyses provide the basis for understanding cerebellar evolution and function.</p