242 research outputs found

    DGNSS Cooperative Positioning in Mobile Smart Devices: A Proof of Concept

    Get PDF
    Global Navigation Satellite System (GNSS) constitutes the foremost provider for geo-localization in a growing number of consumer-grade applications and services supporting urban mobility. Therefore, low-cost and ultra-low-cost, embedded GNSS receivers have become ubiquitous in mobile devices such as smartphones and consumer electronics to a large extent. However, limited sky visibility and multipath scattering induced in urban areas hinder positioning and navigation capabilities, thus threatening the quality of position estimates. This work leverages the availability of raw GNSS measurements in ultralow-cost smartphone chipsets and the ubiquitous connectivity provided by modern, low-latency network infrastructures to enable a Cooperative Positioning (CP) framework. A Proof Of Concept is presented that aims at demonstrating the feasibility of a GNSS-only CP among networked smartphones embedding ultra-low-cost GNSS receivers. The test campaign presented in this study assessed the feasibility of a client-server approach over 4G/LTE network connectivity. Results demonstrated an overall service availability above 80%, and an average accuracy improvement over the 40% w.r.t. to the GNSS standalone solution

    POINT MUTATIONS IN THE TYROSINE KINASE DOMAIN RELEASE THE ONCOGENIC AND METASTATIC POTENTIAL OF THE RON RECEPTOR

    Get PDF

    DXA-Based Detection of Low Muscle Mass Using the Total Body Muscularity Assessment Index (TB-MAXI): A New Index with Cutoff Values from the NHANES 1999–2004

    Get PDF
    The aims of this study were to investigate age-related changes in total body skeletal muscle mass (TBSMM) and the between-limb asymmetry in lean mass in a large sample of adults. Demographic, anthropometric, and DXA-derived data of National Health and Nutrition Examination Survey participants were considered. The sample included 10,014 participants of two ethnic groups (Caucasians and African Americans). The age-related decline of TBSMM absolute values was between 5% and 6% per decade in males and between 4.5% and 5.0% per decade in females. The adjustment of TBSMM for body surface area (TB-MAXI) showed that muscle mass peaked in the second decade and decreased progressively during the subsequent decades. The following thresholds were identified to distinguish between low and normal TB-MAXI: (i) 10.0 kg/m2 and 11.0 kg/m2 in Caucasian and African American females; and (ii) 12.5 kg/m2 and 14.5 kg/m2 in Caucasian and African American males. The lean asymmetry indices were higher for the lower limbs compared with the upper limbs and were higher for males compared with females. In conclusion, the present study proposes the TB-MAXI and lean asymmetry index, which can be used (and included in DXA reports) as clinically relevant markers for muscle amount and lean distribution

    Diagnostic performance of the Strength and Pain Assessment (SPA) score for non-contact muscle injury screening in male soccer players

    Get PDF
    Objectives: The aims of this study were to develop a clinical-feature based scoring system for muscle injury screening and to assess its diagnostic accuracy when large number of injuries are suspected. Methods: A prospective diagnostic accuracy study was performed according to the Standards for Reporting of Diagnostic Accuracy (STARD) criteria. The diagnostic accuracy of the Strength and Pain Assessment (SPA) score (index test) was assessed in relation to muscle ultrasonography (reference standard). A large (n = 175) number of male soccer players met the inclusion/exclusion criteria: clinical assessment (i.e., evaluation of pain onset modality, location, distribution, impact on performance, and manual muscle strength testing) and ultrasonography were performed in all players after 48 hours from the sudden or progressive onset of muscle pain during or after a soccer competition. Results: 91 of 175 cases (52%) were classified as functional muscle disorders, while signs of muscle tear were observed in the remaining 84 of 175 (48%) cases that were classified as structural muscle injuries. The median (1st–3rd quartile) value of the SPA score was significantly (P < 0.001) lower in the functional disorder group [9 (9–10)] compared to the structural injury group [12 (12–13)]. The area under the Receiver Operating Characteristic curve for different cutoff points of the SPA score was 0.977 (95% confidence intervals: 0.957–0.998) and the optimal cutoff value of the SPA score providing the greatest sensitivity and specificity (respectively, 99% and 89%) was 11. Conclusion: This study found that the SPA score has high diagnostic accuracy for structural muscle injuries and could be used as a valid screening tool in soccer players presenting with sudden or progressive onset of muscle pain during or after a competition
    • …
    corecore