3,629 research outputs found
Radio Emission from GRO J1655-40 during the 1994 Jet Ejection Episodes
We report multifrequency radio observations of GRO J1655-40 obtained with the
Australia Telescope Compact Array, the Molonglo Observatory Synthesis Telescope
and the Hartebeesthoek Radio Astronomy Observatory at the time of the major
hard X-ray and radio outbursts in 1994 August-September. The radio emission
reached levels of the order of a few Jy and was found to be linearly polarized
by up to 10%, indicating a synchrotron origin. The light curves are in good
agreement with those measured with the VLA, but our closer time sampling has
revealed two new short-lived events and significant deviations from a simple
exponential decay. The polarization data show that the magnetic field is well
ordered and aligned at right angles to the radio jets for most of the
monitoring period. The time evolution of the polarization cannot be explained
solely in terms of a simple synchrotron bubble model, and we invoke a hybrid
`core-lobe' model with a core which contributes both synchrotron and free-free
emission and `lobes' which are classical synchrotron emitters.Comment: 36 pages, 5 tables, 9 figures; accepted for publication in Ap
Radio Supernova 1987A at 843 MHz
We report the flux densities of the evolving radio source SN1987A at 843 MHz
measured from observations made with the Molonglo Observatory Synthesis
Telescope between 1994 September and 2000 May. The radio light curve shows that
the rate of increase of the flux density jumped markedly around days 2800-3000
(i.e. in the first half of 1995), and that since then the radio evolution has
been remarkably well fitted by a simple linear increase of (62.7 +- 0.5)
microJansky/day. We discuss in detail the relationship between the radio light
curve and the recent brightening of the system at optical wavelengths.Comment: To be published in the Astrophysical Journal, 11 pages, 4 postscript
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The Psy-Security-Curriculum ensemble: British Values curriculum policy in English schools
Framed as being in response to terrorist attacks and concerns about religious bias in some English schools, âBritish Valuesâ (BV) curriculum policy forms part of the British Governmentâs Counter-Terrorism and Security Act, 2015. This includes a Duty on teachers in England to actively promote British Values to deter students from radicalisation. This paper, first, traces the history of Britishness in the curriculum to reveal a prevalence of nationalistic, colonial values. Next, an ensemble of recent policies and speeches focusing on British Values is analysed, using a psycho-political approach informed by anti-colonial scholarship. Finally, we interrogate two key critiques of the British Values curriculum discourse: the universality of British Values globally, and concerns over the securitisation of education. Findings indicate that the constitution of white British supremacist subjectivities operate through curriculum as a defence mechanism against perceived threats to white privilege, by normalising a racialised state-controlled social order. The focus is on âBritishâ values, but the analytic framework and findings have wider global significance
On the making and taking of professionalism in the further education workplace
This paper examines the changing nature of professional practice in English further education. At a time when neo-liberal reform has significantly impacted on this under-researched and over-market-tested sector, little is known about who its practitioners are and how they construct meaning in their work. Sociological interest in the field has tended to focus on further education practitioners as either the subjects of market and managerial reform or as creative agents operating within the contradictions of audit and inspection cultures. In challenging such dualism, which is reflective of wider sociological thinking, the paper examines the ways in which agency and structure combine to produce a more transformative conception of the further education professional. The approach contrasts with a prevailing policy discourse that seeks to re-professionalise and modernise further education practice without interrogating either the terms of its professionalism or the neo-liberal practices in which it resides
Self-diffusion in binary blends of cyclic and linear polymers
A lattice model is used to estimate the self-diffusivity of entangled cyclic
and linear polymers in blends of varying compositions. To interpret simulation
results, we suggest a minimal model based on the physical idea that constraints
imposed on a cyclic polymer by infiltrating linear chains have to be released,
before it can diffuse beyond a radius of gyration. Both, the simulation, and
recently reported experimental data on entangled DNA solutions support the
simple model over a wide range of blend compositions, concentrations, and
molecular weights.Comment: 10 pages, 2 figure
Estimating Individual and Household Reproduction Numbers in an Emerging Epidemic
Reproduction numbers, defined as averages of the number of people infected by a typical case, play a central role in tracking infectious disease outbreaks. The aim of this paper is to develop methods for estimating reproduction numbers which are simple enough that they could be applied with limited data or in real time during an outbreak. I present a new estimator for the individual reproduction number, which describes the state of the epidemic at a point in time rather than tracking individuals over time, and discuss some potential benefits. Then, to capture more of the detail that micro-simulations have shown is important in outbreak dynamics, I analyse a model of transmission within and between households, and develop a method to estimate the household reproduction number, defined as the number of households infected by each infected household. This method is validated by numerical simulations of the spread of influenza and measles using historical data, and estimates are obtained for would-be emerging epidemics of these viruses. I argue that the household reproduction number is useful in assessing the impact of measures that target the household for isolation, quarantine, vaccination or prophylactic treatment, and measures such as social distancing and school or workplace closures which limit between-household transmission, all of which play a key role in current thinking on future infectious disease mitigation
Envelope Determinants of Equine Lentiviral Vaccine Protection
Lentiviral envelope (Env) antigenic variation and associated immune evasion present major obstacles to vaccine development. The concept that Env is a critical determinant for vaccine efficacy is well accepted, however defined correlates of protection associated with Env variation have yet to be determined. We reported an attenuated equine infectious anemia virus (EIAV) vaccine study that directly examined the effect of lentiviral Env sequence variation on vaccine efficacy. The study identified a significant, inverse, linear correlation between vaccine efficacy and increasing divergence of the challenge virus Env gp90 protein compared to the vaccine virus gp90. The report demonstrated approximately 100% protection of immunized ponies from disease after challenge by virus with a homologous gp90 (EV0), and roughly 40% protection against challenge by virus (EV13) with a gp90 13% divergent from the vaccine strain. In the current study we examine whether the protection observed when challenging with the EV0 strain could be conferred to animals via chimeric challenge viruses between the EV0 and EV13 strains, allowing for mapping of protection to specific Env sequences. Viruses containing the EV13 proviral backbone and selected domains of the EV0 gp90 were constructed and in vitro and in vivo infectivity examined. Vaccine efficacy studies indicated that homology between the vaccine strain gp90 and the N-terminus of the challenge strain gp90 was capable of inducing immunity that resulted in significantly lower levels of post-challenge virus and significantly delayed the onset of disease. However, a homologous N-terminal region alone inserted in the EV13 backbone could not impart the 100% protection observed with the EV0 strain. Data presented here denote the complicated and potentially contradictory relationship between in vitro virulence and in vivo pathogenicity. The study highlights the importance of structural conformation for immunogens and emphasizes the need for antibody binding, not neutralizing, assays that correlate with vaccine protection. © 2013 Craigo et al
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