National Crystallography Service (NCS) Grid Service

Conference poster about the NCS Grid Service.The EPSRC funded National Crystallography Service (NCS) is a facility available to the entire UK academic Chemistry community. The EPSRC funds a team of experts and 'state of the art' instrumentation, based in Southampton University School of Chemistry, to provide this service. This is an exceptionally important service as crystal structure determination is easily the most information rich method of characterisation of a compound and many research papers cannot be published without confirmation of identity by crystal structure analysis

Basic Issues in Economic Comparisons of Commercial and Sport Fisheries: A Study of Allocation Alternatives for Alaska Kenai River Sockeye Salmon Fisheries

Allocation between commercial and sport fisheries is becoming an increasingly difficult and divisive issue in fisheries management. As conflicts over allocation have increased, so has interest in the relative economic contributions of commercial and sport fisheries. This paper describes eight basic issues in economic comparisons of commercial and sport fisheries. These basic issues should be considered in evaluating or planning any economic comparison of commercial and sport fisheries--from a back-of-the-envelope comparison to a formal study. We illustrate these issues by describing how they arose in an economic comparison o f commercial and sport fisheries for Alaska's Kenai River sockeye salmon. Prepared for presentation at a session on "The Role of Economics in Fisheries Management" at the 1998 Annual Meeting of the American Fisheries Society Hartford, Connecticut August 24, 199

Scientific Integrity: Producing, Incorporating, and Advocating for Science in the Age of Alternative Facts

Technical information – along with politics, economics, public opinion, societal values, and legal considerations – is one input into wildlife management decisions.  As information consumers, decision-makers require objectivity of those who produce such information, and should have an understanding of the inference scope and strength (and uncertainty) associated with technical information.  Information producers must earn, demonstrate, and protect that reputation of objectivity.  Both producers and consumers must both foster and guard a culture of integrity, such that the processes of producing and applying information are transparent and can withstand intense scrutiny.  Today, rather suddenly, there is national discourse on these subjects of transparency, professional integrity, and rigorous questioning and defense of scientific information.  The discussion of the role of science and scientists in informing public policy has assumed a prominent position in traditional and social media.  This panel, consisting of representatives from federal, state, tribal, and non-governmental organizations will engage in this discussion with the audience

Wolf Management In The Northwestern United States

Gray wolves (Canis lupus) were deliberately eliminated from the northern Rocky Mountains (NRM) by 1930. Restoration began in 1986. There are currently nearly 120 breeding pair and 1800 wolves. Wolf restoration initially proceeded with more benefits and fewer problems than predicted. However, conflicts have steadily increased since 2002 when the population first met its minimum recovery goal. About 40 million has been spent since 1974 and the management program currently costs >4 million/yr. Wolves were delisted in 2008 and 2009 but relisted by federal court order in 2009 and 2010. While the NRM wolf population is biologically recovered, public opinion remains divisive and the legal, political, and policy decisions will continue to be litigated by a diversity of interests. Science is a poor tool to resolve the differing human values that continue to be debated with great passion through wolf symbolism

Rapid growth of HFC-227ea (1,1,1,2,3,3,3-Heptafluoropropane) in the atmosphere

We report the first measurements of 1,1,1,2,3,3,3-heptafluoropropane (HFC-227ea), a substitute for ozone depleting compounds, in remote regions of the atmosphere and present evidence for its rapid growth. Observed mixing ratios ranged from below 0.01 ppt in deep firn air to 0.59 ppt in the northern mid-latitudinal upper troposphere. Firn air samples collected in Greenland were used to reconstruct a history of atmospheric abundance. Year-on-year increases were deduced, with acceleration in the growth rate from 0.026 ppt per year in 2000 to 0.057 ppt per year in 2007. Upper tropospheric air samples provide evidence for a continuing growth until late 2009. Fur- thermore we calculated a stratospheric lifetime of 370 years from measurements of air samples collected on board high altitude aircraft and balloons. Emission estimates were determined from the reconstructed atmospheric trend and suggest that current "bottom-up" estimates of global emissions for 2005 are too high by more than a factor of three

Genotypic and phenotypic spectrum of pyridoxine-dependent epilepsy (ALDH7A1 deficiency)

Pyridoxine-dependent epilepsy was recently shown to be due to mutations in the ALDH7A1 gene, which encodes antiquitin, an enzyme that catalyses the nicotinamide adenine dinucleotide-dependent dehydrogenation of L-{alpha}-aminoadipic semialdehyde/L-{Delta}1-piperideine 6-carboxylate. However, whilst this is a highly treatable disorder, there is general uncertainty about when to consider this diagnosis and how to test for it. This study aimed to evaluate the use of measurement of urine L-{alpha}-aminoadipic semialdehyde/creatinine ratio and mutation analysis of ALDH7A1 (antiquitin) in investigation of patients with suspected or clinically proven pyridoxine-dependent epilepsy and to characterize further the phenotypic spectrum of antiquitin deficiency. Urinary L-{alpha}-aminoadipic semialdehyde concentration was determined by liquid chromatography tandem mass spectrometry. When this was above the normal range, DNA sequencing of the ALDH7A1 gene was performed. Clinicians were asked to complete questionnaires on clinical, biochemical, magnetic resonance imaging and electroencephalography features of patients. The clinical spectrum of antiquitin deficiency extended from ventriculomegaly detected on foetal ultrasound, through abnormal foetal movements and a multisystem neonatal disorder, to the onset of seizures and autistic features after the first year of life. Our relatively large series suggested that clinical diagnosis of pyridoxine dependent epilepsy can be challenging because: (i) there may be some response to antiepileptic drugs; (ii) in infants with multisystem pathology, the response to pyridoxine may not be instant and obvious; and (iii) structural brain abnormalities may co-exist and be considered sufficient cause of epilepsy, whereas the fits may be a consequence of antiquitin deficiency and are then responsive to pyridoxine. These findings support the use of biochemical and DNA tests for antiquitin deficiency and a clinical trial of pyridoxine in infants and children with epilepsy across a broad range of clinical scenarios

Current and future ozone risks to global terrestrial biodiversity and ecosystem processes

Risks associated with exposure of individual plant species to ozone (O3) are well documented, but implications for terrestrial biodiversity and ecosystem processes have received insufficient attention. This is an important gap because feedbacks to the atmosphere may change as future O3 levels increase or decrease, depending on air quality and climate policies. Global simulation of O3 using the Community Earth System Model (CESM) revealed that in 2000, about 40% of the Global 200 terrestrial ecoregions (ER) were exposed to O3 above thresholds for ecological risks, with highest exposures in North America and Southern Europe, where there is field evidence of adverse effects of O3, and in central Asia. Experimental studies show that O3 can adversely affect the growth and flowering of plants and alter species composition and richness, although some communities can be resilient. Additional effects include changes in water flux regulation, pollination efficiency, and plant pathogen development. Recent research is unraveling a range of effects belowground, including changes in soil invertebrates, plant litter quantity and quality, decomposition, and nutrient cycling and carbon pools. Changes are likely slow and may take decades to become detectable. CESM simulations for 2050 show that O3 exposure under emission scenario RCP8.5 increases in all major biomes and that policies represented in scenario RCP4.5 do not lead to a general reduction in O3 risks; rather, 50% of ERs still show an increase in exposure. Although a conceptual model is lacking to extrapolate documented effects to ERs with limited or no local information, and there is uncertainty about interactions with nitrogen input and climate change, the analysis suggests that in many ERs, O3 risks will persist for biodiversity at different trophic levels, and for a range of ecosystem processes and feedbacks, which deserves more attention when assessing ecological implications of future atmospheric pollution and climate change

The Ursinus Weekly, May 13, 1971

\u2771 CCC forms plans for frosh • H. Salisbury of New York Times to speak at 1971 Commencement • U.C. Sigma Xi chooses new \u2771 members • Campus Chest caps drive with carnival • Application trend up as class of 1975 fills • Area lacrosse squad packed by U.C. girls • Editorial: New McCarthy era on the way? • The cutback • Ursinus grading system often causes problems • Mrs. Gil, Mr. Sorensen leave U.C. faculty • Proposed Limerick power plant presents serious complications • Letters to the editor: J\u27Accuse; Frankly, Scarlett • Movie critic: Father hears no songs • Trackmen finish 7-1 for year; Fourth place in \u2771 MAC meet • Ursinus did it; Beat Swarthmore • Golf team number 10; Peter Allen number 8https://digitalcommons.ursinus.edu/weekly/1146/thumbnail.jp

An anatomy of economic inequality in the UK: report of the National Equality Panel.

Britain is an unequal country, more so than many other industrial countries and more so than a generation ago. This is manifest in many ways - most obviously in the gap between those who are well off and those who are less well off. But inequalities in people's economic positions are also related to their characteristics - whether they are men or women, their ages, ethnic backgrounds, and so on. The independent National Equality Panel, was established at the invitation of the Rt. Hon. Harriet Harman, Minister for Equality to report on the relationships between inequalities in economic outcomes and differences related to people's characteristics.