2,339 research outputs found

    The Effects of Family Income, Geography, and Structure on Juvenile Crime

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    This paper looks to explore the effect that family income, geography, and structure have on juvenile crime. These three categories have all been theorized and researched, which will help to provide a backbone for this paper. Though there are many other factors that have been linked to juvenile crime, I will focus only on these three

    The District of Cochrane Social Services Administration Board: An Analysis of the Provincial Objectives Driving Its Formation and the Organization’s Capacity to Meet These Objectives

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    This paper examines whether the short- and long-term goals surrounding the Ontario government’s decision to create district social services administration boards have been met based on a case study of the Cochrane District Social Services Administration Board (CDSSAB). The findings reveal that the province’s short-term objectives have been met and, although many challenges persist, the CDSSAB is well positioned to meet the long-term objectives of efficiency, less government, and superior integrated services

    Citizens on Twitter: A Rhetorical Analysis of Emerging Political Satire

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    This thesis provides an overview of the history of satire, its rhetorical structure, and my interpretation of its historically culminated five fundamental characteristics. I also introduce that the rise in popularity of American political satire through various media has inspired a new wave of American satirists who project their own political satirical messages through social media platforms and how Twitter, in particular, has provided those average individuals with the opportunity to more actively, directly, and satirically take part in political discussions. With a collection of two data sets of tweets—one larger live tweet sweep during the first 2016 presidential debate and a study of five average individual political satirists\u27 tweets throughout a majority of the 2016 presidential campaign and after—I analyze how these tweets command a legitimacy into the established satirical realm because of their adherence to the fundamental characteristics presented. I also analyze how this particular social media platform affects these texts\u27 productions through the challenges presented to satirists and strategies that have emerged to combat those challenges. I then discuss the implications for and opportunities provided to average American citizens as political satirical commentators on Twitter in the changing world of American politics

    Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in Flock House virus RNA replication

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    Abstract Background Cellular membranes are crucial host components utilized by positive-strand RNA viruses for replication of their genomes. Published studies have suggested that the synthesis and distribution of membrane lipids are particularly important for the assembly and function of positive-strand RNA virus replication complexes. However, the impact of specific lipid metabolism pathways in this process have not been well defined, nor have potential changes in lipid expression associated with positive-strand RNA virus replication been examined in detail. Results In this study we used parallel and complementary global and targeted approaches to examine the impact of lipid metabolism on the replication of the well-studied model alphanodavirus Flock House virus (FHV). We found that FHV RNA replication in cultured Drosophila S2 cells stimulated the transcriptional upregulation of several lipid metabolism genes, and was also associated with increased phosphatidylcholine accumulation with preferential increases in lipid molecules with longer and unsaturated acyl chains. Furthermore, targeted RNA interference-mediated downregulation of candidate glycerophospholipid metabolism genes revealed a functional role of several genes in virus replication. In particular, we found that downregulation of Cct1 or Cct2, which encode essential enzymes for phosphatidylcholine biosynthesis, suppressed FHV RNA replication. Conclusion These results indicate that glycerophospholipid metabolism, and in particular phosphatidylcholine biosynthesis, plays an important role in FHV RNA replication. Furthermore, they provide a framework in which to further explore the impact of specific steps in lipid metabolism on FHV replication, and potentially identify novel cellular targets for the development of drugs to inhibit positive-strand RNA viruses.http://deepblue.lib.umich.edu/bitstream/2027.42/78268/1/1471-2164-11-183.xmlhttp://deepblue.lib.umich.edu/bitstream/2027.42/78268/2/1471-2164-11-183-S3.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78268/3/1471-2164-11-183-S2.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78268/4/1471-2164-11-183.pdfhttp://deepblue.lib.umich.edu/bitstream/2027.42/78268/5/1471-2164-11-183-S4.XLShttp://deepblue.lib.umich.edu/bitstream/2027.42/78268/6/1471-2164-11-183-S1.XLSPeer Reviewe

    High resolution palaeoclimatology of the Holocene Sub Polar North Atlantic

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    A high resolution multiproxy investigation of two marine cores from the Gardar Drift in the Sub Polar North Atlantic, cores MD99-2251 and MD99-2252 has been undertaken to examine the extent of Holocene climate variability reflected by changes in diatom floral abundances and ice rafted debris flux. The results from this study provide both an overview of climate variability for the entire Holocene as recorded in the Sub Polar North Atlantic and a detailed high resolution study focussed around the 8.2kyr event. Sea surface temperature (SST) estimates are derived using a weighted average partial least squares (WAPLS) transfer function and a new regionally based diatom transfer function developed as part of this study. Principal component analysis and K-means cluster analysis were undertaken on core MD99-2251 to identify floral groupings within the diatom taxa. The changing composition of diatom assemblages and SST records indicate a highly unstable early Holocene from 11.5 to 9.5kyr with switches in the dominance of cool Sub Arctic floras and warmer North Atlantic floras. The presence of high productivity events in the diatom floras during this interval suggests that the core locations were, at times, in close proximity of the Sub Arctic Front. A broad SST cooling from 9.5 to 7kyr is identified followed by a pronounced warming for 7 to 5kyr and more stable but cooler temperatures during the Late Holocene. Changes in sea surface hydrography, especially the relative strength of the warm Irminger Current, is considered to have had the greatest influence on the composition of diatom floral assemblages. The 8.2kyr event is not recognised as a discrete climate perturbation in either the diatom assemblage data or the IRD record, but is contained within the broad cooling event from 9.5-7kyr. Analysis of sea-ice and cold water flora however does indicate some increase in these species for the interval 8.8 to 7.8kyr

    Motivating Factors and Barriers to the Online Faculty Professional Development

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    A capstone submitted in partial fulfillment of the requirements for the degree of Doctor of Education in the College of Education at Morehead State University by Kathryn L. Miller on April 16, 2015

    Resurrecting Arbitrariness

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    What allows judges to sentence a child to die in prison? For years, they did so without constitutional restriction. That all changed in 2012’s Miller v. Alabama, which banned mandatory sentences of life without parole for children convicted of homicide crimes. Miller held that this extreme sentence was constitutional only for the worst offenders—the “permanently incorrigible.” By embracing individualized sentencing, Miller and its progeny portended a sea change in the way juveniles would be sentenced for serious crimes. But if Miller opened the door to sentencing reform, the Court’s recent decision in Jones v. Mississippi appeared to slam it shut. Rather than restrict the discretion of a judge to throw away the key in sentencing child defendants, the Court in Jones increased that discretion. It recast Miller as a purely procedural decision that only required a barebones “consideration” of a defendant’s “youth and attendant characteristics” to fulfill its mandate of individualized sentencing. Jones further held that judges need not engage in any formal factfinding before sentencing a child to die in prison, which renders these sentences nearly unreviewable. This Article argues that, through these two jurisprudential moves, Jones created conditions that will maximize arbitrary and racially discriminatory sentencing outcomes nationwide, resembling the unconstitutional death sentences of the mid-twentieth century. This Article is the first to comprehensively analyze Jones, contending that the decision represents an embrace of unfettered discretion in the sentencing of children facing life without parole. Given the Supreme Court’s gutting of the Eighth Amendment, I contend that state solutions are the way forward. I propose that states join the national trend of abandoning life without parole sentences for children. Short of abolishing the sentence, I offer three procedural interventions. First, states should enact “genuine narrowing” requirements that establish criteria designed to limit eligibility for life without parole sentences for children to the theoretical “worst of the worst.” While inspired by the narrowing requirement in capital sentencing, “genuine narrowing” relies on meaningful and concrete criteria that seek to achieve the mandate of Miller that such sentences be uncommon. Second, states should require jury sentencing, which ensures that sentences will be imposed by multiple, and typically more diverse, voices than what currently occurs with judicial sentencing. Third, states should go beyond merely telling sentencers to take youth into account in their sentencing decisions, but should instead inform them that the characteristics of youth are “mitigating as a matter of law,” and when present, must weigh against an imposition of life without parole

    The Public Record Office: A Study of the Creation of the Office and the Construction of Its Fireproof Repository

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    At the beginning of the nineteenth century Britain\u27s public records were scattered among more than fifty depositories which were overcrowded, unorganized, neglected, and ill-suited to record preservation. The British government was not sympathetic to the condition or the importance of the records. How then did the British government become involved in creating the Public Record Office and building its first fireproof repository? This study takes the form of a chronology based extensively on the records of the Public Record Office, the Office of Works, and the British Sessional Papers. Although the creation of the Public Record Office was part of a larger preservation movement in the nineteenth century, in fact, it was the result of the efforts of a few devoted individuals. The design and construction of Britain\u27s central archive was the result of the efforts of one architect--James Pennethorne

    The Eighth Amendment Power to Discriminate

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    For the last half-century, Supreme Court doctrine has required that capital jurors consider facts and characteristics particular to individual defendants when determining their sentences. While liberal justices have long touted this individualized sentencing requirement as a safeguard against unfair death sentences, in practice the results have been disappointing. The expansive discretion that the requirement confers on overwhelmingly White juries has resulted in outcomes that are just as arbitrary and racially discriminatory as those that existed in the years before the temporary abolition of the death penalty in Furman v. Georgia.1 After decades of attempting to eliminate the requirement, conservative justices have recently employed a new tactic: extinction through expansion. By relying on the individualized sentencing requirement to discourage jury instructions that enhance consideration of mitigation evidence, these justices have stretched the doctrine well beyond its intended meaning. This broad interpretation renders individualized sentencing ephemeral to the point of insignificance, ensuring that the problems with capital sentencing will continue in the years to come. While an examination of individualized sentencing is overdue, the solution is not to jettison the requirement, but instead to permit states to channel juror discretion. This Article is the first to contend that states may achieve the goals of individualized sentencing, not by expanding juror discretion to consider mitigation evidence, but, counterintuitively, by narrowing it. It proposes that states employ specific jury instructions that: (1) require jurors to consider certain types of evidence as legally mitigating; (2) address the historically racist application of the death penalty; and (3)permit unfettered discretion solely in the direction of leniency. Channeling and redirecting discretion will minimize racist and arbitrary outcomes and realize true individualized sentencing
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