362 research outputs found

    About Culture in Economics

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    The formal precision of modern economics, with its theoretical abstraction, its mathematical analytics and its reliance on disinterested scientific method in testing hypotheses about how economic system behave, might suggest that economics as a discipline does not have a cultural context, that it operates within a world that is not considered by, nor conditional upon, any cultural phenomena. But just as the radical critique described of contemporary economics has argued that the sort of economics described above cannot be value‐free, so also can it be suggested that economics as an intellectual cannot be culture‐free

    Systemic inflammation and residual viraemia in HIV-positive adults on protease inhibitor monotherapy: a cross-sectional study.

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    Increased levels of markers of systemic inflammation have been associated with serious non-AIDS events even in patients on fully suppressive antiretroviral therapy. We explored residual viremia and systemic inflammation markers in patients effectively treated with ritonavir-boosted protease inhibitor monotherapy (PImono)

    Статус інституту прокуратури в системі органів державної влади України

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    У статті розглядається проблема місця та ролі органів прокуратури в механізмі державної влади. На основі аналізу та класифікації різних моделей інституціональної взаємодії прокуратури з іншими гілками влади автор виділяє окрему гілку влади - контрольно-наглядову. Ключові слова: інституційна взаємодія, інтеграція прокуратури, контрольно-наглядова гілка влади.В статье рассматривается проблема места и роли органов прокуратуры в механизме государственной власти. На основе анализа и классификации разных моделей институционального взаимодействия прокуратуры с другими ветвями власти автор выделяет отдельную ветвь власти - контрольно-наблюдательную. Ключевые слова: институциональное взаимодействие, интеграция прокуратуры, контрольно-наблюдательная ветвь власти.The problem of the role and the place of procuratorship in the state mechanism is covered in the article. According to the analyzing and classificating different modals of institutional interactions with other branches of government the author points out separate branch of government . supervising one. Key words: institutional interaction, integration of procuratorship, supervising branch of government

    Risky Alcohol Consumption and Associated Health Behaviour Among HIV-Positive and HIV-Negative Patients in a UK Sexual Health and HIV Clinic: A Cross-Sectional Questionnaire Study

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    Alcohol misuse has been associated with negative consequences among HIV-positive patients. Data on real prevalence of risky alcohol consumption among the HIV-positive population in the UK are lacking. A cross-sectional questionnaire study using standardised validated instruments among HIV-positive (n = 227) and HIV-negative (n = 69) patients was performed. The prevalence of risky alcohol consumption (AUDIT) and associations with depressive symptoms (PHQ-9), problematic drug use (DUDIT), adherence to ART (CASE Adherence Index), sexual behaviour and demographic characteristics were assessed among both patient groups independently. A quarter (25.1%) of HIV-positive patients and 36.1% of HIV-negative patients reported risky alcohol consumption (AUDIT-score ≥ 8). In the multivariable analysis among HIV-positive patients depressive symptoms (p = 0.03) and problematic drug use (p = 0.007) were associated with risky alcohol consumption. Among HIV-negative patients these associations were not present. Risky alcohol consumption among HIV-positive patients is prevalent, and together with depressive symptoms and problematic drug use, may influence HIV-disease progression and patients’ wellbeing

    Two vicious circles associated with the aging of the immune system in the development of severe forms of COVID-19

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    Background: The immune-inflammatory response is the basis of the pathophysiology of SARS-Cov-2 infection. In severe cases of COVID-19 uncontrolled systemic inflammatory response causes multiorgan dysfunction (MODS), as the most common immediate cause of death. Unfavorable outcome of the COVID-19 most often occurs in elderly patients. The aim of the study was to establish parameters with prognostic significance in severe cases of COVID-19 according to life years, laboratory markers of sepsis and MODS, as well as the number of peripheral CD4+ and CD8+T lymphocytes in 20 consecutively selected critically ill patients.Results: Eleven subjects were male, 9 female, mean age 73.45 ± 11.59, among which the oldest patient was 94 and the youngest 43 years. All the patients met the sepsis and MODS criteria. Increased age and low CD4+ and CD8+T cell counts were identified as independent predictors of death. Only the two youngest patients (43 and 50 years old) survived 28 days, and they are the only ones with a CD4 lymphocyte count above 500 cells/mm3.Conclusion: Senescence of the immune system is mostly characterized by reduced regenerative capacity of adaptive immunity with diminished ability to respond to new antigens and a manifested proinflammatory phenotype. Additional reduction of protective capacity by further deterioration of T cell quantity and quality due to sepsis itself and mutual interaction of senescent T cells and vascular endothelial cells in the induction of cytokine storm represent two complementary vicious cycles in the development of sepsis-related multiorgan dysfunction

    Glassy dynamics in monodisperse hard ellipsoids

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    We present evidence from computer simulations for glassy dynamics in suspensions of monodisperse hard ellipsoids. In equilibrium, almost spherical ellipsoids show a first order transition from an isotropic phase to a rotator phase. When overcompressing the isotropic phase into the rotator regime, we observe super-Arrhenius slowing down of diffusion and relaxation, accompanied by two-step relaxation in positional and orientational correlators. The effects are strong enough for asymptotic laws of mode-coupling theory to apply. Glassy dynamics are unusual in monodisperse systems. Typically, polydispersity in size or a mixture of particle species is prerequisite to prevent crystallization. Here, we show that a slight particle anisometry acts as a sufficient source of disorder. This sheds new light on the question of which ingredients are required for glass formation.Comment: included data of prolate system in all figures and text, extended discussion of indicators of glassy dynamics, fixed symbol ambiguities, preprint forma

    The seasonal detection of strawberry viruses in Victoria, Australia

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    AbstractPCR tests were adopted from international, peer-reviewed literature and developed for the detection of Strawberry mottle sadwavirus (SMoV), Strawberry crinkle cytorhabdovirus (SCV), Strawberry mild yellow edge potexvirus (SMYEV), Strawberry vein banding caulimovirus (SVBV), Beet pseudos yellows crinivirus (BPYV), and Strawberry pallidosis associated crinivirus (SPaV) in Victoria, Australia. The PCR tests were applied to 23 positive control plants infected with one or more viruses and these plants have been tested monthly from May 2005 to April 2007. Our results have indicated that the viruses were most reliably detected by PCR during May-October. In November, December and January of each year a decline in the number of positive PCR results for BPYV, SVBV and SPaV was observed. Twelve positive control plants maintained at the AQIS post entry quarantine screenhouse at Knoxfield, Victoria, and also infected with one or more viruses, were tested monthly from August 2006 to April 2007. A similar decline in the ability to detect SMoV, SVBV and SPaV in the AQIS positive control plants was observed in 2006/07 and November was the least reliable month for detection of strawberry viruses in these plants. These results indicate that spring and autumn may be the optimal times for PCR detection of strawberry viruses in south east Australia.Keywords: Strawberry mottle sadwavirus; Strawberry crinkle cytorhabdovirus; Strawberry mild yellow edge potexvirus; Strawberry vein banding caulimovirus; Beet pseudos yellows crinivirus; Strawberry pallidosis associated crinivirus; detection; polymerase chain reaction; PCR; certificatio

    Fast Neutron And Gamma-ray Detectors For The Csiro Air Cargo Scanner

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    oS(FNDA2006)074 © Copyright owned by the author(s) under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike Licence
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