15 research outputs found

    БлСдСњС Π½Π° Ρ€Π΅Π΄ΡƒΠΊΡ†ΠΈΡ˜Π° ΠΈ ΠΎΠ΄Ρ€ΠΆΡƒΠ²Π°ΡšΠ΅ Π½Π° пСрипростСтично коскСно Ρ‚ΠΊΠΈΠ²ΠΎ кај Π±Π΅Π·Ρ†Π΅ΠΌΠ΅Π½Ρ‚Π½Π° ΠΏΡ€ΠΈΠΌΠ°Ρ€Π½Π° Π΅Π½Π΄ΠΎΠΏΡ€ΠΎΡ‚Π΅Π·Π° Π½Π° ΠΊΠΎΠ»ΠΊ со Π°Π»Π΅Π½Π΄Ρ€ΠΎΠ½Π°Ρ‚Π½Π° Ρ‚Π΅Ρ€Π°ΠΏΠΈΡ˜Π°

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    Loss of periprosthetic bone tissue in primary hip endoprostheses is common in clinical practice. This loss can be progressive and in extreme conditions can jeopardize the longevity of the prosthesis. In order to monitor the function of Alendronate therapy for bone maintenance, the study included 50 patients with implanted total cement-free hip endoprosthesis (TPH). The first group of 25 patients received Alendronate, calcium and vitamin D3 orally postoperatively. The second group of 25 patients were examined postoperatively without therapy. Patients were followed by radiographic and dual-energy X-ray absorptiometry (DXA) at 6 and 12 months. The study showed that in patients with TPH there was a difference in the X-ray findings as well as occurrence of osteolysis in certain Gruen zones, which was confirmed by changes in the state of bone mineral density (BMD) and bone mineral content (BMC) in the interval between 6 and 12 months using the DXA method. Alendronate therapy after TPH implantation allows reduction of periprosthetic bone mass loss, maintenance of bone mineralization and implant hardening.Π“ΡƒΠ±Π΅ΡšΠ΅Ρ‚ΠΎ Π½Π° пСрипростСтичното коскСно Ρ‚ΠΊΠΈΠ²ΠΎ кај ΠΏΡ€ΠΈΠΌΠ°Ρ€Π½ΠΈΡ‚Π΅ Π΅Π½Π΄ΠΎΠΏΡ€ΠΎΡ‚Π΅Π·ΠΈ Π½Π° ΠΊΠΎΠ»ΠΊΠΎΡ‚ Π΅ чСста појава Π²ΠΎ ΠΊΠ»ΠΈΠ½ΠΈΡ‡ΠΊΠ°Ρ‚Π° пракса. Π’Π°ΠΊΠ²ΠΈΠΎΡ‚ Π³ΡƒΠ±ΠΈΡ‚ΠΎΠΊ ΠΌΠΎΠΆΠ΅ Π΄Π° Π±ΠΈΠ΄Π΅ прогрСсивСн ΠΈ Π²ΠΎ СкстрСмни услови Π΄Π° ја Π·Π°Π³Ρ€ΠΎΠ·ΡƒΠ²Π° Π΄ΠΎΠ»Π³ΠΎΡ‚Ρ€Π°Ρ˜Π½ΠΎΡΡ‚Π° Π½Π° ΠΏΡ€ΠΎΡ‚Π΅Π·Π°Ρ‚Π°.   Π—Π°Ρ€Π°Π΄ΠΈ Π½Π°Π±Π»ΡƒΠ΄ΡƒΠ²Π°ΡšΠ΅ Π½Π° Ρ„ΡƒΠ½ΠΊΡ†ΠΈΡ˜Π°Ρ‚Π° Π½Π° Π°Π»Π΅Π½Π΄Ρ€ΠΎΠ½Π°Ρ‚Π½Π°Ρ‚Π° Ρ‚Π΅Ρ€Π°ΠΏΠΈΡ˜Π° Π·Π° ΠΎΠ΄Ρ€ΠΆΡƒΠ²Π°ΡšΠ΅ Π½Π° коскСното Ρ‚ΠΊΠΈΠ²ΠΎ  Π²ΠΎ ΡΡ‚ΡƒΠ΄ΠΈΡ˜Π°Ρ‚Π° Π±Π΅Π° Π²ΠΊΠ»ΡƒΡ‡Π΅Π½ΠΈ 50 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ со Π²Π³Ρ€Π°Π΄Π΅Π½Π° Ρ‚ΠΎΡ‚Π°Π»Π½Π° Π±Π΅Π·Ρ†Π΅ΠΌΠ΅Π½Ρ‚Π½Π° Π΅Π½Π΄ΠΎΠΏΡ€ΠΎΡ‚Π΅Π·Π° Π½Π° ΠΊΠΎΠ»ΠΊ (ВПК). ΠŸΡ€Π²Π°Ρ‚Π° Π³Ρ€ΡƒΠΏΠ° ΠΎΠ΄ 25 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ постопСративно  ΠΏΡ€ΠΈΠΌΠ°Π°  ΠΎΡ€Π°Π»Π½ΠΎ  Π°Π»Π΅Π½Π΄Ρ€ΠΎΠ½Π°Ρ‚, ΠΊΠ°Π»Ρ†ΠΈΡƒΠΌ ΠΈ Π²ΠΈΡ‚Π°ΠΌΠΈΠ½ Π”3. Π’Ρ‚ΠΎΡ€Π°Ρ‚Π° Π³Ρ€ΡƒΠΏΠ° ΠΎΠ΄ 25 пациСнтипостопСративно  Π±Π΅Π° ислСдувани  Π±Π΅Π· ΠΏΡ€ΠΈΠΌΠ΅Π½Π° Π½Π° Ρ‚Π΅Ρ€Π°ΠΏΠΈΡ˜Π°. ΠŸΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈΡ‚Π΅ Π±Π΅Π° слСдСни со радиографски ΠΈ двојно-СнСргСтска Ρ€Π΅Π½Π΄Π³Π΅Π½Π·Ρ€Π°Ρ‡Π½Π° Π°ΠΏΡΠΎΡ€ΠΏΡ‚ΠΎΠΌΠ΅Ρ‚Ρ€ΠΈΡ˜Π°  (DXA) Π½Π° 6 ΠΈ 12 мСсСци.  Π‘Ρ‚ΡƒΠ΄ΠΈΡ˜Π°Ρ‚Π° ΠΏΠΎΠΊΠ°ΠΆΠ°  Π΄Π΅ΠΊΠ° кај ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈΡ‚Π΅ со ВПК  постои Ρ€Π°Π·Π»ΠΈΠΊΠ° Π²ΠΎ Π Π’Π“ Π½Π°ΠΎΠ΄ΠΈΡ‚Π΅ ΠΊΠ°ΠΊΠΎ ΠΈ  појава Π½Π° остСолиза Π²ΠΎ ΠΎΠ΄Ρ€Π΅Π΄Π΅Π½ΠΈ Gruenovi Π·ΠΎΠ½ΠΈ, ΡˆΡ‚ΠΎΡΠ΅ ΠΏΠΎΡ‚Π²Ρ€Π΄ΠΈ со ΠΏΡ€ΠΎΠΌΠ΅Π½ΠΈ ΠΈ Π²ΠΎ ΡΠΎΡΡ‚ΠΎΡ˜Π±Π°Ρ‚Π°  Π½Π° врСдноститС Π½Π° коскСната ΠΌΠΈΠ½Π΅Ρ€Π°Π»Π½Π° густина(BMD) ΠΈ коскСната ΠΌΠΈΠ½Π΅Ρ€Π°Π»Π½Π°  содрТина (BMC) Π²ΠΎ ΠΈΠ½Ρ‚Π΅Ρ€Π²Π°Π»ΠΎΡ‚ ΠΏΠΎΠΌΠ΅Ρ“Ρƒ 6 ΠΈ 12  мСсСци  со помош Π½Π° DXA  ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΎΡ‚. АлСндронатната Ρ‚Π΅Ρ€Π°ΠΏΠΈΡ˜Π° ΠΏΠΎ Π²Π³Ρ€Π°Π΄ΡƒΠ²Π°ΡšΠ΅ Π½Π° ВПК ΠΎΠ²ΠΎΠ·ΠΌΠΎΠΆΡƒΠ²Π° Π½Π°ΠΌΠ°Π»ΡƒΠ²Π°ΡšΠ΅ Π½Π° пСрипростСтичната Π·Π°Π³ΡƒΠ±Π° Π½Π° коскСната маса, ΠΎΠ΄Ρ€ΠΆΡƒΠ²Π°ΡšΠ΅ Π½Π° ΠΌΠΈΠ½Π΅Ρ€Π°Π»ΠΈΠ·Π°Ρ†ΠΈΡ˜Π°Ρ‚Π° Π½Π° коскСното Ρ‚ΠΊΠΈΠ²ΠΎ ΠΈ Π·Π°Ρ†Π²Ρ€ΡΡ‚ΡƒΠ²Π°ΡšΠ΅ Π½Π° ΠΈΠΌΠΏΠ»Π°Π½Ρ‚ΠΎΡ‚

    ΠŸΡ€ΠΈΡΡƒΡΡ‚Π²ΠΎ Π½Π° Π°Π½Ρ‚ΠΈ-Π’Π€4/Ρ…Π΅ΠΏΠ°Ρ€ΠΈΠ½ Π°Π½Ρ‚ΠΈΡ‚Π΅Π»Π° кај ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ ΠΏΡ€ΠΎΡ„ΠΈΠ»Π°ΠΊΡ‚ΠΈΡ‡ΠΊΠΈ Ρ‚Ρ€Π΅Ρ‚ΠΈΡ€Π°Π½ΠΈ со Сноксапарин послС ортопСдски ΠΎΠΏΠ΅Ρ€Π°Ρ‚ΠΈΠ²Π΅Π½ Π·Π°Ρ„Π°Ρ‚

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    Heparin-induced thrombocytopenia (HIT) is a condition caused by antibodies against the platelet factor 4 (PF4)/heparin complex. This significantly increases the risk of bleeding and thrombosis in patients, which is essential in the postoperative period. In this study we examined the rate of seroconversion of anti-PF4/heparin antibodies in patients with rheumatoid arthritis (RA) and osteoarthritis (OA) after total knee or hip arthroplasty. The aims of the study were to assess the risk of HIT by evaluation of induction of anti-PF4/heparin antibodies in patients with RA and OA after total knee or hip arthroplasty, treated prophylactically with enoxaparine. Material and methods: We followed 36 patients aged 18 to 80 years, after total knee or hip arthroplasty, treated prophylactically with enoxaparine. Patients were divided in two groups: patients with RA and patients with OA.Β  They were examined for occurrence of HIT. Blood was sampled twice, from a peripheral vein, for immunologic tests. The first time it was done before enoxaparine application and the second time postoperatively 10 days after surgery. We noted demographic data, anti-PF4/heparin antibodies, erythrocyte sedimentation rate (ESR), CRP, RF, antiCCP and anti-nuclear antibodies Hep2 (ANA). Results: There was no significant difference in the values of anti-PF4/heparin antibodies in patients with RA and OA preoperatively. The presence of anti-PF4/heparin antibodies was significantly lower in RA patients compared to OA (7.14% versus 27.27%, p=0.034). There was no significant association between levels of anti-PF4/heparin antibodies and ESR, CRP, RF, CCP, ANA. Conclusion: The results obtained showed a lower level of anti-PF4/heparin antibodies in patients with RA than in patients with OA. This shows that there may be a difference in the generation of this antibody in patients with RA compared to patients with OA, prophylactically treated with enoxaparine after total knee or hip arthroplasty.Π₯Π΅ΠΏΠ°Ρ€ΠΈΠ½-ΠΈΠ½Π΄ΡƒΡ†ΠΈΡ€Π°Π½Π°Ρ‚Π° Ρ‚Ρ€ΠΎΠΌΠ±ΠΎΡ†ΠΈΡ‚ΠΎΠΏΠ΅Π½ΠΈΡ˜Π° (Π₯ИВ) Π΅ ΠΏΡ€Π΅Π΄ΠΈΠ·Π²ΠΈΠΊΠ°Π½Π° ΠΎΠ΄ Π°Π½Ρ‚ΠΈΡ‚Π΅Π»Π° ΠΊΠΎΠ½ Ρ‚Ρ€ΠΎΠΌΠ±ΠΎΡ†ΠΈΡ‚Π½ΠΈΠΎΡ‚ Ρ„Π°ΠΊΡ‚ΠΎΡ€ 4 (Π’Π€4)/Ρ…Π΅ΠΏΠ°Ρ€ΠΈΠ½ комплСксот. Π’Π°Π° Π·Π½Π°Ρ‡ΠΈΡ‚Π΅Π»Π½ΠΎ Π³ΠΎ Π·Π³ΠΎΠ»Π΅ΠΌΡƒΠ²Π° Ρ€ΠΈΠ·ΠΈΠΊΠΎΡ‚ ΠΎΠ΄ ΠΊΡ€Π²Π°Π²Π΅ΡšΠ΅ ΠΈ Ρ‚Ρ€ΠΎΠΌΠ±ΠΎΠ·Π° кај ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈΡ‚Π΅, ΡˆΡ‚ΠΎ Π΅ особСно Π΅ΡΠ΅Π½Ρ†ΠΈΡ˜Π°Π»Π½ΠΎ Π²ΠΎ постопСративниот ΠΏΠ΅Ρ€ΠΈΠΎΠ΄. Π’ΠΎ ΠΎΠ²Π°Π° ΡΡ‚ΡƒΠ΄ΠΈΡ˜Π° ја ΠΏΡ€ΠΎΡ†Π΅Π½ΡƒΠ²Π°ΠΌΠ΅ стапката Π½Π° ΡΠ΅Ρ€ΠΎΠΊΠΎΠ½Π²Π΅Ρ€Π·ΠΈΡ˜Π° Π½Π° Π°Π½Ρ‚ΠΈ-Π’Π€4/Ρ…Π΅ΠΏΠ°Ρ€ΠΈΠ½ Π°Π½Ρ‚ΠΈΡ‚Π΅Π»Π°Ρ‚Π° кај ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ со Ρ€Π΅Π²ΠΌΠ°Ρ‚ΠΎΠΈΠ΄Π΅Π½ артритис ΠΈ остСоартритис ΠΏΠΎ ΠΈΠΌΠΏΠ»Π°Π½Ρ‚Π°Ρ†ΠΈΡ˜Π° Π½Π° ΠΏΡ€ΠΎΡ‚Π΅Π·Π° Π½Π° ΠΊΠΎΠ»ΠΊ ΠΈΠ»ΠΈ ΠΊΠΎΠ»Π΅Π½ΠΎ Π»Π΅ΠΊΡƒΠ²Π°Π½ΠΈ ΠΏΡ€ΠΎΡ„ΠΈΠ»Π°ΠΊΡ‚ΠΈΡ‡ΠΊΠΈ со Сноксапарин. Π¦Π΅Π»Ρ‚Π° Π½Π° ΠΈΡΡ‚Ρ€Π°ΠΆΡƒΠ²Π°ΡšΠ΅Ρ‚ΠΎ бСш Π΄Π° сС ΠΏΡ€ΠΎΡ†Π΅Π½ΠΈ Ρ€ΠΈΠ·ΠΈΠΊΠΎΡ‚ ΠΎΠ΄ Ρ…Π΅ΠΏΠ°Ρ€ΠΈΠ½-ΠΈΠ½Π΄ΡƒΡ†ΠΈΡ€Π°Π½Π° Ρ‚Ρ€ΠΎΠΌΠ±ΠΎΡ†ΠΈΡ‚ΠΎΠΏΠ΅Π½ΠΈΡ˜Π° ΠΏΡ€Π΅ΠΊΡƒ Π΅Π²Π°Π»ΡƒΠ°Ρ†ΠΈΡ˜Π° Π½Π° ΠΈΠ½Π΄ΡƒΠΊΡ†ΠΈΡ˜Π°Ρ‚Π° Π½Π° Π°Π½Ρ‚ΠΈ-Π’Π€4/Ρ…Π΅ΠΏΠ°Ρ€ΠΈΠ½ Π°Π½Ρ‚ΠΈΡ‚Π΅Π»Π°Ρ‚Π° кај ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ со Ρ€Π΅Π²ΠΌΠ°Ρ‚ΠΎΠΈΠ΄Π΅Π½ артритис ΠΈ остСоартритис ΠΏΠΎ ΠΈΠΌΠΏΠ»Π°Π½Ρ‚Π°Ρ†ΠΈΡ˜Π° Π½Π° ΠΏΡ€ΠΎΡ‚Π΅Π·Π° Π½Π° ΠΊΠΎΠ»Π΅Π½Π° ΠΈΠ»ΠΈ ΠΊΠΎΠ»ΠΊ, Π»Π΅ΠΊΡƒΠ²Π°Π½ΠΈ ΠΏΡ€ΠΎΡ„ΠΈΠ»Π°ΠΊΡ‚ΠΈΡ‡ΠΊΠΈ со Сноксапарин. ΠœΠ°Ρ‚Π΅Ρ€ΠΈΡ˜Π°Π» ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄ΠΈ: Π‘Π΅Π° испитани 36 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ, Π½Π° возраст ΠΎΠ΄ 18 Π΄ΠΎ 80 Π³ΠΎΠ΄ΠΈΠ½ΠΈ, ΠΏΠΎ ΠΈΠΌΠΏΠ»Π°Π½Ρ‚Π°Ρ†ΠΈΡ˜Π° Π½Π° ΠΏΡ€ΠΎΡ‚Π΅Π·Π° Π½Π° ΠΊΠΎΠ»ΠΊ ΠΈΠ»ΠΈ ΠΊΠΎΠ»Π΅Π½ΠΎ, Π»Π΅ΠΊΡƒΠ²Π°Π½ΠΈ ΠΏΡ€ΠΎΡ„ΠΈΠ»Π°ΠΊΡ‚ΠΈΡ‡ΠΊΠΈ со Сноксапарин. ΠŸΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈΡ‚Π΅ Π±Π΅Π° ΠΏΠΎΠ΄Π΅Π»Π΅Π½ΠΈ Π²ΠΎ Π΄Π²Π΅ Π΅Π΄Π½Π°ΠΊΠ²ΠΈ Π³Ρ€ΡƒΠΏΠΈ, односно ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ со Ρ€Π΅Π²ΠΌΠ°Ρ‚ΠΎΠΈΠ΄Π΅Π½ артритис (РА) ΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ со остСоартритис (ОА). ΠŸΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈΡ‚Π΅ Π±Π΅Π° слСдСни Π·Π° Π²Ρ€Π΅ΠΌΠ΅ Π½Π° Ρ…ΠΎΡΠΏΠΈΡ‚Π°Π»ΠΈΠ·Π°Ρ†ΠΈΡ˜Π°Ρ‚Π° Π½Π° ΠšΠ»ΠΈΠ½ΠΈΠΊΠ°Ρ‚Π° Π·Π° ортопСдски болСсти Π·Π° појава Π½Π° Π₯ИВ. Π’ΠΎ Π΄Π²Π° Π½Π°Π²Ρ€Π°Ρ‚Π° бСшС Π·Π΅ΠΌΠ΅Π½Π° вСнска ΠΊΡ€Π², ΠΎΠ΄ ΠΏΠ΅Ρ€ΠΈΡ„Π΅Ρ€Π½Π° Π²Π΅Π½Π°, Π·Π° ΠΈΠΌΡƒΠ½ΠΎΠ»ΠΎΡˆΠΊΠΈ ΠΈΡΠ»Π΅Π΄ΡƒΠ²Π°ΡšΠ°. ΠŸΡ€Π² ΠΏΠ°Ρ‚ Ρ‚ΠΎΠ° бСшС Π½Π°ΠΏΡ€Π°Π²Π΅Π½ΠΎ ΠΏΡ€Π΅Π΄ ΠΏΠΎΡ‡Π΅Ρ‚ΠΎΠΊ Π½Π° Π»Π΅ΠΊΡƒΠ²Π°ΡšΠ΅ со Сноксапарин, Π° Π²Ρ‚ΠΎΡ€ ΠΏΠ°Ρ‚ постопСративно, 10 Π΄Π΅Π½Π° ΠΏΠΎ ΠΎΠΏΠ΅Ρ€Π°Ρ‚ΠΈΠ²Π½ΠΈΠΎΡ‚ Π·Π°Ρ„Π°Ρ‚. Π‘Π΅Π° Π½ΠΎΡ‚ΠΈΡ€Π°Π½ΠΈ дСмографски ΠΏΠΎΠ΄Π°Ρ‚ΠΎΡ†ΠΈ, Π°Π½Ρ‚ΠΈ-Π’Π€4/Ρ…Π΅ΠΏΠ°Ρ€ΠΈΠ½ Π°Π½Ρ‚ΠΈΡ‚Π΅Π»Π°, ΡΠ΅Π΄ΠΈΠΌΠ΅Π½Ρ‚Π°Ρ†ΠΈΡ˜Π° Π½Π° Π΅Ρ€ΠΈΡ‚Ρ€ΠΎΡ†ΠΈΡ‚ΠΈ (ESR), CRP, RF, CCP, ANA, појава Π½Π° Π₯ИВ. Π Π΅Π·ΡƒΠ»Ρ‚Π°Ρ‚ΠΈ: НСмашС сигнификантна Ρ€Π°Π·Π»ΠΈΠΊΠ° Π²ΠΎ врСдноститС Π½Π° Π°Π½Ρ‚ΠΈ-Π’Π€4/Ρ…Π΅ΠΏΠ°Ρ€ΠΈΠ½ кај ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈΡ‚Π΅ со ОА ΠΈ РА ΠΏΡ€Π΅Π΄ΠΎΠΏΠ΅Ρ€Π°Ρ‚ΠΈΠ²Π½ΠΎ. Π‘Ρ‚Π°ΠΏΠΊΠ°Ρ‚Π° Π½Π° Π°Π½Ρ‚ΠΈ-Π’Π€4/Ρ…Π΅ΠΏΠ°Ρ€ΠΈΠ½ Π°Π½Ρ‚ΠΈΡ‚Π΅Π»Π° кај ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈΡ‚Π΅ со РА бСшС сигнификантно пониска ΠΎΠ΄ ΠΎΠ½Π°Π° кај ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈΡ‚Π΅ со ОА (7,14% наспроти 27,27%, Ρ€=0,034). НСмашС сигнификантна поврзаност Π½Π° врСдноститС Π½Π° Π°Π½Ρ‚ΠΈ-Π’Π€/4 Π°Π½Ρ‚ΠΈΡ‚Π΅Π»ΠΎΡ‚ΠΎ со врСдноститС Π½Π° ESR, CRP, RF, CCP ΠΈΠ»ΠΈ ANA. Π—Π°ΠΊΠ»ΡƒΡ‡ΠΎΠΊ: Π Π΅Π·ΡƒΠ»Ρ‚Π°Ρ‚ΠΈΡ‚Π΅ ΡƒΠΊΠ°ΠΆΠ°Π° Π½Π° Π½Π°ΠΌΠ°Π»Π΅Π½Π° ΠΈΠ½Ρ†ΠΈΠ΄Π΅Π½Ρ†ΠΈΡ˜Π° Π½Π° Π°Π½Ρ‚ΠΈ-Π’Π€4/Ρ…Π΅ΠΏΠ°Ρ€ΠΈΠ½ Π°Π½Ρ‚ΠΈΡ‚Π΅Π»Π° кај ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈΡ‚Π΅ со РА Π²ΠΎ спорСдба со ΠΎΠ½ΠΈΠ΅ со ОА. Ова ΡƒΠΊΠ°ΠΆΡƒΠ²Π° Π΄Π΅ΠΊΠ° постои Ρ€Π°Π·Π»ΠΈΠΊΠ° Π²ΠΎ Π°Π½Ρ‚ΠΈ-Π’Π€4/Ρ…Π΅ΠΏΠ°Ρ€ΠΈΠ½ ΠΈΠΌΡƒΠ½ΠΈΠΎΡ‚ ΠΎΠ΄Π³ΠΎΠ²ΠΎΡ€ кај ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΈ со РА наспроти ΠΎΠ½ΠΈΠ΅ со ОА, ΠΏΡ€ΠΎΡ„ΠΈΠ»Π°ΠΊΡ‚ΠΈΡ‡ΠΊΠΈ Π»Π΅ΠΊΡƒΠ²Π°Π½ΠΈ со Сноксапарин, ΠΏΠΎ ортопСдски ΠΎΠΏΠ΅Ρ€Π°Ρ‚ΠΈΠ²Π΅Π½ Π·Π°Ρ„Π°Ρ‚ Π·Π° ΠΈΠΌΠΏΠ»Π°Π½Ρ‚Π°Ρ†ΠΈΡ˜Π° Π½Π° ΠΏΡ€ΠΎΡ‚Π΅Π·Π° Π½Π° ΠΊΠΎΠ»ΠΊ ΠΈΠ»ΠΈ ΠΊΠΎΠ»Π΅Π½ΠΎ

    The Influence of Anterior Cruciate Ligament Remnant on Postoperative Clinical Results in Patients with Remnant Preserving Anterior Cruciate Ligament Reconstruction

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    BACKGROUND: Anterior Cruciate Ligament (ACL) remnants have important biomechanical, vascular and proprioceptive function.AIM: To determine the influence of the ACL residual remnants after partial and complete ACL ruptures on postoperative clinical results in patients with remnant preserving ACL reconstruction.PATIENTS AND METHODS: The study included 66 patients divided into two groups. In patients from the investigation group remnant preserving ACL reconstruction was performed, in patients from the control group single bundle ACL reconstruction was performed. The results were assessed by Rolimeter measurements, Lysholm and Tegner scores and proprioception evaluation.RESULTS: The mean side-to-side difference of anterior tibia displacement (mm) was improved from 4.4 ± 1.06 to 0.4 ± 0.7 in the investigation group, and from 4.6 ± 0.68 to 1.9 ± 0.64 in the control group (p < 0.001). Difference in the angles in which the knee was placed by the device and the patient has improved from 1.5 ± 0.96° to 0.5 ± 0.53° in the investigation group and from 1.8 ± 0.78° to 1.3 ± 0.97° in the control group (p < 0.05).  Tegner and Lysholm scores showed no difference between the groups.CONCLUSION: Preservation of the ACL residual bundle provides a better knee stability and proprioceptive function

    Intracapsular and para- articular chondroma of knee: a report of four cases and review of the literature

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    Intracapsular and para-articular chondroma is a rare variant of the extraskeletal chondromas. It arises from the capsule and/or the para-articular connective tissue of the large joints (mostly the knee) and is a result of cartilaginous metaplasia. In course of time these tumors ossify and this is where their second name comes from: Para-articular osteochondromas. According to Jaffe, not dependent on the degree of ossification of this tumor, there is one single entity in question

    Computer assisted diagnosis of benign bone tumours

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    The aim of this study is to determine the correlation between computer-assisted diagnosis(CAD) of benign bone tumours (BBT) and their histological type. Diagnosis and treatment of benign bone tumours (BBT) is a multidisciplinary task. Teams of diverse subspecialists are involved in the process. Good quality plain X-rays may be most helpful in 9 of 10 cases. Bone scan, CT and MRI are additionally needed for the diagnosis, staging and decision making on the management of BBT. The diagnosis of histological type can be done exclusively by a patohistyologist

    Radiologic-pathologic correlation of 100 consecutive biopsied soft tissue musculoskeletal lesions after multimodality imaging.

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    To correlate radiologic imaging diagnosis with histopathology in cases with soft tissue musculoskeletal lesions. Before ultrasound (US)-guided core needle biopsy, radiologic imaging diagnosis was done using multimodality imaging. Correlation of histopathologic Method: diagnoses after biopsy and surgical specimen was done

    Diagnostic and treatment problems with parosteal osteosarcoma. A clinical and a histological study of 7 cases and review of the literature

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    Parosteal osteosarcoma is a rare low-grade bone tumour. The operation material must undergo a careful patohistological analysis, because the extent of invasion of the medullar cavity and most probably the extent of dedifferentiated areas determines the prognosis and occurrence of local recurrence and metastases
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