OPM database and PPM web server: resources for positioning of proteins in membranes

The Orientations of Proteins in Membranes (OPM) database is a curated web resource that provides spatial positions of membrane-bound peptides and proteins of known three-dimensional structure in the lipid bilayer, together with their structural classification, topology and intracellular localization. OPM currently contains more than 1200 transmembrane and peripheral proteins and peptides from approximately 350 organisms that represent approximately 3800 Protein Data Bank entries. Proteins are classified into classes, superfamilies and families and assigned to 21 distinct membrane types. Spatial positions of proteins with respect to the lipid bilayer are optimized by the PPM 2.0 method that accounts for the hydrophobic, hydrogen bonding and electrostatic interactions of the proteins with the anisotropic water-lipid environment described by the dielectric constant and hydrogen-bonding profiles. The OPM database is freely accessible at http://opm.phar.umich.edu. Data can be sorted, searched or retrieved using the hierarchical classification, source organism, localization in different types of membranes. The database offers downloadable coordinates of proteins and peptides with membrane boundaries. A gallery of protein images and several visualization tools are provided. The database is supplemented by the PPM server (http://opm.phar.umich.edu/server.php) which can be used for calculating spatial positions in membranes of newly determined proteins structures or theoretical models

Uranyl Sulfate Nanotubules Templated by N-phenylglycine

The synthesis, structure, and infrared spectroscopy properties of the new organically templated uranyl sulfate Na(phgH+)7[(UO2)6(SO4)10](H2O)3.5 (1), obtained at room temperature by evaporation from aqueous solution, are reported. Its structure contains unique uranyl sulfate [(UO2)6(SO4)10]8− nanotubules templated by protonated N-phenylglycine (C6H5NH2CH2COOH)+. Their internal diameter is 1.4 nm. Each of the nanotubules is built from uranyl sulfate rings sharing common SO4 tetrahedra. The template plays an important role in the formation of the complex structure of 1. The aromatic rings are stacked parallel to each other due to the effect of π–π interaction with their side chains extending into the gaps between the nanotubules

Dimethyl-​silyl-​bridged-​1-​substituted-​2-​indenyl metallocene complexes for olefin polymerization, polymerization of olefins and to polymers

The metallocene complex is dimethylsilylene-​bridged-​1-​substituted-​2-​indenyl ligand of Ti, Zr or Hf. The metallocene complex catalyst is for prepg. polyolefins, a process for polymg. olefins and to polymers prepd. by the catalyst system

Dihydrocarbyl-​silyl-​bridged-​1,​3 disubstituted-​2-​indenyl metallocene complexes for olefin polymerization

The invention relates to a metallocene complexes, I (R1 = C1-​10 alkyl, C6-​20 aryl, C7-​20 aralkyl groups, C1-​10 alkoxy groups; R2 = H, C1-​10 alkyl; R3-​R6, R10 = H, C1-​10 alkyl, C6-​10 aryl, R3 and R4, R4 and R5, or R5 and R6 can be connected to form a ring structure; M = Ti, Zr, Hf, X = anionic ligand to M, z is the no. of X groups and equals the valence of M minus 2, and wherein each R7 independently is selected from C1-​6 alkyl or aryl groups)​. The invention also relates to a catalyst comprising the reaction product of the metallocene complex and a cocatalyst. Further the invention relates to a (co)​polymn. process of olefinic monomers

Dihydrocarbyl-silyl-bridged-substituted cyclopentadienyl metallocene complexes for olefin polymerization

he invention relates to a metallocene complexes, I (R1 = C2-​10 alkyl, preferably C3-​10 alkyl, C6-​20 aryl, C7-​20 aralkyl; R2 = H, C1-​10 alkyl; R3, R4, R5, R6 = H, C1-​10 alkyl, C6-​20 aryl, C7-​20 aralkyl groups and wherein R3 and R4, R4 and R5, or R5 and R6 can be connected to form a ring structure; M = Ti, Zr, Hf; X = an anionic ligand to M)​. The invention also relates to a catalyst comprising the reaction product of the metallocene complex and a cocatalyst. Further the invention relates to a (co)​polymn. process of olefinic monomers