G4RNA: an RNA G-quadruplex database

Abstract: G-quadruplexes (G4) are tetrahelical structures formed from planar arrangement of guanines in nucleic acids. A simple, regular motif was originally proposed to describe G4-forming sequences. More recently, however, formation of G4 was discovered to depend, at least in part, on the contextual backdrop of neighboring sequences. Prediction of G4 folding is thus becoming more challenging as G4 outlier structures, not described by the originally proposed motif, are increasingly reported. Recent observations thus call for a comprehensive tool, capable of consolidating the expanding information on tested G4s, in order to conduct systematic comparative analyses of G4-promoting sequences. The G4RNA Database we propose was designed to help meet the need for easily-retrievable data on known RNA G4s. A user-friendly, flexible query system allows for data retrieval on experimentally tested sequences, from many separate genes, to assess G4-folding potential. Query output sorts data according to sequence position, G4 likelihood, experimental outcomes and associated bibliographical references. G4RNA also provides an ideal foundation to collect and store additional sequence and experimental data, considering the growing interest G4s currently generate

Additional file 2: of Extent of pre-translational regulation for the control of nucleocytoplasmic protein localization

Classification of all NLS motifs considered in this study, including their sequence, class, regulation modes, number of encoding transcripts and number of encoding exons. (XLSX 23 kb

Melaleuca leucadendron L.

原著和名: カユプテ科名: フトモモ科 = Myrtaceae採集地: 台湾 士林 (台湾省 土林)採集日: 1968/9/1採集者: 萩庭丈壽整理番号: JH048602国立科学博物館整理番号: TNS-VS-99860