ABOUT RISK PROCESS ESTIMATION TECHNIQUES EMPLOYED BY A VIRTUAL ORGANIZATION WHICH IS DIRECTED TOWARDS THE INSURANCE BUSINESS

In a virtual organization directed on the insurance business, the estimations of the risk process and of the ruin probability are important concerns: for researchers, at the theoretical level, and for the management of the company, as these influence the insurer strategy. We consider the evolution over an extended period of time of the insurer surplus process. In this paper, we present some methods for the estimation of the ruin probability and for the evaluation of a reserve fund. We discuss the ruin probability with respect to: the parameters of the individual claim distribution, the load factor of premiums and the intensity parameter of the number of claims process. We analyze the model in which the premiums are computed according to the mean value principle. Also, we attempt the case when the initial capital is proportional to the expected value of the individual claim. We give numerical illustration.virtual organization, ruin probability, risk process, adjustment coefficient

ADAPTING THE THEORY TO REALITY. THE TRIAD GLOBALIZATION-PROTECTIONISM-ECONOMIC PATRIOTISM

A science is adjusting and developing in time – on this trajectory the evolution of economic science is situated. The emergence of new concepts, as well as re-theorizing of some traditional concepts comes to support this viewpoint. In order to demonstraprotectionism, globalization, economic patriotism.

Changing Methodologies in Financial Audit and Their Impact on Information Systems Audit

This paper tries to provide a better understanding of the relation between financial audit and information systems audit and to assess the influence the change in financial audit methodologies had on IS audit. We concluded that the COSO Internal Control – Integrated Framework was the starting point for fundamental changes in both financial and IS audit and that the Sarbanes-Oxley Act should be viewed as an enabler rather than an enforcer in establishing strong governance models. Finally, our research suggests that there is a direct causality effect between the employment of BRA (business risk audit) methodologies and the growing importance of IS audit

Reverse logistics and space allocation for recovery management in new urban settlements

This paper presents the authors’ vision about the planning foundation for the new residential areas from the large cities outskirts, in a sustainable development framework. One considers the great generation potential of the high and very high income population in case of the used products with remained reuse value, or new and undesired products, available in the residential places. We propose a space allocation model with a hexagonal hierarchical structure for the centralized return centers in a reverse logistics. The space allocation model for the recovery centers implementation takes into consideration: the recovery habits, environmental care and sustainable development education, “moral” compensations, centralized recovery centers facilities, walking willingness of the average inhabitant of the considered area, decision makings involvement at the local Public Authority level, and local community. One reveals the importance of the data collecting stage for the potential and availability of the exhausted products (having reuse value) in a specific area with high and very high income populationreverse logistics; centralized return centres; recovery potential; space allocation

Decisions of hypermarkets location in dense urban area – effects on streets network congestion in the Bucharest case

The paper represents some partial results of the research carried out by the Transportation, Traffic and Logistics Department - University POLITEHNICA of Bucharest, funded by the Romanian Ministry of Research and Education through the National University Research Council. In this paper we provide: a brief description of the interrelation between the life style changes of Romanian people during the last decades and the car traffic congestion in large cities; the streets network modelling of a radial-circular urban structure (the characteristic of a historically developed city as Bucharest city is), in case of car traffic congestion; the assessment model of the additional car traffic congestion for certain locations with large attractivity. Having an important effect on the entire lifestyle of urban people, the decision of a hypermarket location might be a complex one, taking into consideration the new leisure and shopping tendencies but also the additional car traffic congestion caused by the chosen location

Influence of the freight transnational rail liner service on the train scheduling in case of major corridors

In this paper we discuss several consequences of the freight transnational rail liner service on the rail corridor capacity. The Northern part of the IVth TEN-T corridor on Romanian territory has specific feature related to the passenger flows connecting important Romanian demographic and economic clusters, on one side, and on the other side, to its diagonal crossing aspect, from the Western border to the Constanta port, connecting the Central Europe countries to the Black Sea regions, which means that there are a lot of expectation in terms of this corridor rail capacity: this corridor will, be for a long time further, the single and first completed continuous upgraded and modernised rail corridor. Its utilization will necessarily be heterogeneously planned (meaning for passengers rapid trains and freight rapid trains, from domestic/internal market, but especially for external market of Romania). In this paper, we consider a simple mathematical model for the calculus of capacity in two different cases: for a homogeneous utilization, meaning that all trains have the same running speeds and for heterogeneous utilization, when the passenger trains have the higher speed and hence, the higher priority over the freight trains, even if some of them are freight transnational liner service. Special feature of liner rail service has to be considered (fixed schedule, no stops for passenger train advance). We draw several useful possible solutions to be considered in order to preserve the active corridor capacity, and to assure a smooth flow for the transnational liner services, which ultimately will enhance the rail attractiveness

Recurrent intraoral HSV-1 infection : a retrospective study of 58 immunocompetent patients from Eastern Europe

Objectives. To revise the clinical features of the recurrent intraoral herpetic infection (RIOH) with respect to precipitating factors, demographic, clinical features and outcome. Study design. Fifty-eight, unrelated Caucasian, immunocompetent patients with positive laboratory test for intraoral Herpes simplex virus infection were studied. Results. The mean age in the women?s group (n=42) was 41.23 years (± 21.73) and in the men?s group was 32.25 years (± 15.68). Possible trigger factors were identified in 9 cases (15.5%). General symptoms were noted in 20 cases (34.48%). Most of patients in this study presented multiple lesions. 14 patients had vermillion lesions associated with intraoral lesions. In most of the cases both fixed and mobile mucosa was concomitantly involved. Treatment was prescribed in order to control the symptoms and to shorten the evolution with minimal side effects. Conclusions. Intraoral secondary herpetic infection could be polymorphous and sometimes associated with general symptoms. The recognition of its atypical features may prevent unnecessary and costly investigations and treatments for unrelated though clinically similar-appearing disorders

Oral lichen planus: a retrospective study of 633 patients from Bucharest, Romania

Objective: In this retrospective study, patients' medical records were reviewed to investigate the profiles of 633 OLP cases in a group of Romania. Material and Methods: In this retrospective study, the following clinical data were obtained from the medical charts of patients: gender, age, clinical presentation of OLP, site affected, presence of symptoms, extraoral manifestations of lichen planus, presence of systemic diseases, and history of medications. Results: Most (78.67%) OLP patients were female and the mean age at presentation was 52 years. The white type of the disease (reticular/papular/plaque lesions) was the main form encountered in this sample (48.97%). Among patients with available hepatitis C virus test results, 9.6% were serum-positive. OLP was associated with gallbladder disease (i.e. cholecystitis, cholelithiasis) in 19% of patients. Six patients (0.95%) developed squamous cell carcinoma at a site with confirmed OLP lesions. Conclusions: To the best of our knowledge, no similar study has been conducted in a Romanian population. The present investigation revealed the predominance of OLP among middle-aged white women and the prevalence of bilateral involvement of the buccal mucosa with reticular white lesions. Anti-HCV circulating antibodies were more common in patients with OLP than in the general population and, notably, OLP was associated with gallbladder disease (cholecystitis, cholelithiasis) in 19% of patients

EVOLUTION OF WINTER WHEAT CROP UNDER THE INFLUENCE OF AGROTEHNICAL MEASURES AND CLIMATE CHANGES

In the context of climate change, crop technologies must be updated and adapted by identifying and implementing new technological links regarding: soil tillages, the fertilization system, the previous plant, which will contribute to significantly reducing the negative impact of climate change on production and quality for wheat crop. The relationship production - quality - technology highlighted the negative influence of excessive temperatures and deficient precipitation in important stages in the evolution of plants. Wheat yield and quality are affected by management practices, climate conditions and genetic characteristics. The research was carried out in the period 2019 – 2021, in the experimental field of NARDI Fundulea and the purpose of this study was to evaluate the effect of agrotechnical measures and climatic conditions on the yield and quality of wheat. The experiment involved three different soil works and four fertilized options. Yields and quality were maximized by associated factors. Soil conservation works associated with manure fertilization increase production values and final quality by 5-10%, depending on the variant

How opportune is multigene testing in metastatic colorectal cancer? A review

Personalized treatment in oncology is the most innovative method of care. The best method to establish personalized treatment is by genetic characterization of the malignant cell. Theoretically, the more detailed the characterization, the more effective the choice of treatment becomes. Currently, there are fast and relatively low-cost options that allow such genetic characterization. However, test results sometimes do not detect targetable alterations and, even if they do detect, the use of the treatment-alteration combination does not always generate a satisfactory oncological response. The present paper aims to answer two questions. First, how targetable can the most common gene alterations in colorectal cancer be. Second, whether it makes sense to use broad molecular testing as a standard in all metastatic patients