Dynamical fermion masses under the influence of Kaluza-Klein fermions in extra dimensions

The dynamical fermion mass generation in the 4-dimensional brane is discussed in a model with 5-dimensional Kaluza-Klein fermions in interaction with 4-dimensional fermions. It is found that the dynamical fermion masses are generated beyond the critical radius of the compactified extra dimensional space and may be made small compared with masses of the Kaluza-Klein modes.Comment: 11 pages, 3 figures, REVTeX; typos corrected, comment about the symmetry breaking added in section 4, new references for section 1 adde

Advanced Gastric Neuroendocrine Carcinoma with an Adenocarcinoma Component

In the present study, we observed that the adenocarcinoma component in the mucosa was continuous with neuroendocrine carcinoma (NEC) in the deeper layers; this suggests the normal course of NEC carcinogenesis at the histological level. A 72-year-old man was admitted to our hospital with a chief complaint of tarry stools. Endoscopic examination of the upper gastrointestinal tract revealed a 2-cm tumor, with a deep central depression, surrounded by a smooth elevated area, in the middle of the stomach body. A biopsy showed that the tumor was a moderately differentiated gastric adenocarcinoma. The patient underwent total gastrectomy and standard lymph node dissection. The resected tumor was a 3.5 × 2.5 cm type 2 lesion. It comprised two elements at the histological level: (i) a moderately differentiated adenocarcinoma in the superficial portion of the mucous membrane layer, and (ii) NEC-like cells with dark, round nuclei and scant cytoplasm, presenting a solid and trabecular pattern, in the submucosal and muscularis propria layers. Immunohistochemical findings showed that the NEC-like cells were diffusely positive for chromogranin A, synaptophysin, neural cell adhesion molecule, and neuron-specific enolase, but were negative for carcinoembryonic antigen. The Ki-67 labeling index was 95%. The final pathological diagnosis was gastric NEC with an adenocarcinoma component and a high cellular proliferative potential

Gasdermin Cは、大腸癌においてApc変異の存在下でTGFβII型受容体の不活化により発現亢進し、癌細胞の増殖を亢進する。

内容の要旨 , 審査の要旨広島大学(Hiroshima University)博士(医学)Doctor of Philosophy in Medical Sciencedoctora

ナタネ種実のGoitrogenic Substanceに関する研究 : (第2報) Oxazolidinethioneを生成するthioglucosidesの加熱による破壊

Effect of heating two kinds of rapeseed and their meal under various conditions was examined on destruction of thioglucosides contained in them which may impart toxity and unpalatability to them by changing themselves into oxazolidinethiones. The thioglucosides were easily destroyed by autoclaving, of which the optimum conditions were; 150 min. at 120℃ for Brassica napus seed, 50 min. at 120℃ for B. napus defatted meal, and 100 min. at 100℃ for B. campestris seed oil meal; whereas dry-heating treatments were not only ineffective but also resulted in more serious toxity and unpalatability than the untreated sample