7,485 research outputs found

    How alternative food networks work in a metropolitan area? An analysis of Solidarity Purchase Groups in Northern Italy

    Get PDF
    Our paper focuses on Solidarity Purchase Group (SPG) participants located in a highly urbanized area, with the aim to investigate the main motivations underlining their participation in a SPG and provide a characterization of them. To this end, we carried out a survey of 795 participants involved in 125 SPGs in the metropolitan area of Milan (Italy). Taking advantage of a questionnaire with 39 questions, we run a factor analysis and a two-step cluster analysis to identify different profiles of SPG participants. Our results show that the system of values animating metropolitan SPG practitioners does not fully conform to that traditionally attributed to an alternative food network (AFN). In fact, considerations linked to food safety and healthiness prevail on altruistic motives such as environmental sustainability and solidarity toward small producers. Furthermore, metropolitan SPGs do not consider particularly desirable periurban and local food products. Observing the SPGs from this perspective, it emerges as such initiatives can flourish also in those places where the lack of connection with the surrounding territory is counterbalanced by the high motivation to buy products from trusted suppliers who are able to guarantee genuine and safe products, not necessarily located nearby

    Kinetics and functional consequences of BK channels activation by N-type Ca2+ channels in the dendrite of mouse neocortical layer-5 pyramidal neurons

    Get PDF
    The back-propagation of an action potential (AP) from the axon/soma to the dendrites plays a central role in dendritic integration. This process involves an intricate orchestration of various ion channels, but a comprehensive understanding of the contribution of each channel type remains elusive. In this study, we leverage ultrafast membrane potential recordings (Vm) and Ca2+ imaging techniques to shed light on the involvement of N-type voltage-gated Ca2+ channels (VGCCs) in layer-5 neocortical pyramidal neurons’ apical dendrites. We found a selective interaction between N-type VGCCs and large-conductance Ca2+-activated K+ channels (BK CAKCs). Remarkably, we observe that BK CAKCs are activated within a mere 500 μs after the AP peak, preceding the peak of the Ca2+ current triggered by the AP. Consequently, when N-type VGCCs are inhibited, the early broadening of the AP shape amplifies the activity of other VGCCs, leading to an augmented total Ca2+ influx. A NEURON model, constructed to replicate and support these experimental results, reveals the critical coupling between N-type and BK channels. This study not only redefines the conventional role of N-type VGCCs as primarily involved in presynaptic neurotransmitter release but also establishes their distinct and essential function as activators of BK CAKCs in neuronal dendrites. Furthermore, our results provide original functional validation of a physical interaction between Ca2+ and K+ channels, elucidated through ultrafast kinetic reconstruction. This insight enhances our understanding of the intricate mechanisms governing neuronal signaling and may have far-reaching implications in the field

    The Beauty of the Commons? Consumers participation in Food Community Networks

    Get PDF
    Why are consumers increasingly joining farmers to co-produce and transact sustainable foods world-wide? May these networks be a new tool to promote sustainable practices? As stated by Sandler (2010): “Longitudinal collective action environmental problems are likely to be effectively addressed only by an enormous number of individuals each making a nearly insignificant contribution to resolving them”. Consumers-farmers networks may serve this scope by inducing individual actors to change their preferences towards sustainable products. However participation in these networks is still not well understood. On one hand new institutional economics explains consumers joining farmers in creating a network as a choice of the “most cost-economizing” governance structure to carry out a transaction where credence attributes are involved (i.e. sustainable-produced foodstuff). Thus a credence food is transacted through a consumers-farmers network if this governance structure can ensure the minimization of the transaction costs. However the way different (transactional) contexts can influence the change of consumers perceptions and preferences for credence foods is still not completely addressed. On the other hand behavioral economics underlines the role of social and psychological motivations such as altruism and fairness, to describe this type of decision making process. Still a clear link between transaction costs, motivations and the choice context to describe consumers participation in these networks is not completely understood and analysed. In this paper we use both new institutional and behavioural economics arguments to conceptualize the consumers participation in this new type of governance structures, which we have defined as food community network (FCN). More specifically we have investigated an Italian fast-spreading type of FCN named Solidarity Purchase Group . GAS are associations of consumers whose behavior is characterized by a strong philosophical and ethical agreement in which the territorial, economic and social ties between the individuals involved in it, tend to evolve into networks of participative economy. The present study, which is part of a wider study financed by the Sicilian Regional Authority, analyses the GAS presence in Sicily (a region in Southern Italy), where 32 active GAS are present, representing an estimated number of 1,200 families. Although this phenomenon is still marginal and limited to recent years, it can be particularly interesting because of its rapid proliferation. Attention to this type of participative consumerism is warranted for two reasons: firstly, because of its progressive expansion into rural areas, far from the main cities where the phenomenon originated, and secondly, because of its potential impact on the sustainability of food production in this region. To evaluate the potential impact of this phenomenon in Sicily a sample of involved consumers has been interviewed. This sample included some 200 individuals (those in the household in charge of buying) belonging to the main GAS operating in Sicily. This group represents 946 consumers. More specifically a survey was developed to investigate consumers participation in this GAS. In the questionnaire three main issues have been investigated: transaction costs, motivations and social preferences (i.e. altruism and trust), and choice context features as driving factors of consumers participation. Moreover we controlled for i) attitudes towards environmental protection and nature, industrial food production, technological progress, animal welfare, food and environment; ii) consumption frequencies and type of purchased products (i.e. organic, other certified products, conventional products, environmental friendly products and not certified products); and iii) socio-demographic characteristics of the respondents, including food-related lifestyle (FRL). The transaction-costs-related, motivational and choice-context-related variables have used to analyse different level of participation, comparing results from a conditional logit model with a latent-class one. Results indicate different factors affecting participation and profiles of GAS participants, which we can classify as follow: environmentalism and ecological sensitivity (1); gourmet, innovations and creativity (2); cultural patriotism and ethnocentrism (3); animal welfarism (4); cost and price awareness (5); belief in food traditionalism and purity of cuisine (6). Based on these results policy implications have been drawn to promote public support of GAS and food community networks both in the Italian and European contexts

    Robust stationary entanglement of two coupled qubits in independent environments

    Full text link
    The dissipative dynamics of two interacting qubits coupled to independent reservoirs at nonzero temperatures is investigated, paying special attention to the entanglement evolution. The counter-rotating terms in the qubit-qubit interaction give rise to stationary entanglement, traceable back to the ground state structure. The robustness of this entanglement against thermal noise is thoroughly analyzed, establishing that it can be detected at reasonable experimental temperatures. Some effects linked to a possible reservoir asymmetry are brought to light.Comment: 8 pages, 6 figures; version accepted for publication on Eur. Phys. J.

    Application of the Maximum Power Extrapolation Procedure for Human Exposure Assessment to 5G Millimeter Waves: Challenges and Possible Solutions

    Get PDF
    This paper describes an investigation on the application of the Maximum Power Extrapolation (MPE) technique on a fully operational Fixed Wireless Access (FWA) FR2-band 5G gNB. The data was acquired in [27.1-27.3] GHz band using a network scanner over nearly 10 minutes periods to allow a statistical analysis and an accurate estimation of the role of each contribution to the total uncertainty, including the fading affecting the 5G FR2 reference signal. The results show that the level of the electromagnetic field is well below the limits imposed by Italian legislation. However the goal of the paper is more fundamental, and shows an approach that can be used to identify the critical elements of the measurement set-up, suggesting where to concentrate efforts to improve the measurement procedure. In particular, the uncertainty budget highlights three contributions, (i.e. estimation of the traffic beam level, of the probe response and of the 5G FR2 reference signal) that deserve further investigations

    BMQ

    Full text link
    BMQ: Boston Medical Quarterly was published from 1950-1966 by the Boston University School of Medicine and the Massachusetts Memorial Hospitals. Pages 49-52, v17n2, provided courtesy of Howard Gotlieb Archival Research Center

    Innovation and valorization in supply chain network

    Get PDF

    Theodicy and End-of-Life Care

    Get PDF
    Acknowledgments The section on Islamic perspective is contributed by information provided by Imranali Panjwani, Tutor in Theology & Religious Studies, King's College London.Peer reviewedPublisher PD

    Neuron splitting in compute-bound parallel network simulations enables runtime scaling with twice as many processors

    Get PDF
    Neuron tree topology equations can be split into two subtrees and solved on different processors with no change in accuracy, stability, or computational effort; communication costs involve only sending and receiving two double precision values by each subtree at each time step. Splitting cells is useful in attaining load balance in neural network simulations, especially when there is a wide range of cell sizes and the number of cells is about the same as the number of processors. For compute-bound simulations load balance results in almost ideal runtime scaling. Application of the cell splitting method to two published network models exhibits good runtime scaling on twice as many processors as could be effectively used with whole-cell balancing
    corecore