182 research outputs found
Power scalable TEM(oo) CW Nd: YAG laser with thermal lens compensation
We present finite-element analyzes and experimental results to validate our approach for building high-power single-mode Nd:YAG lasers. We show that the thermooptical and thermomechanical properties of a slab laser can be controlled. This is essential for the use of the proposed unstable resonator. We include demonstration of an efficient subscale laser operating at 20 W TEM00.D. Mudge, M. Ostermeyer, P. J. Veitch, J. Munch, B. Middlemiss, D. J. Ottaway and M. W. Hamilto
Energy and symmetry of excitations in undoped layered cuprates measured by Cu resonant inelastic x-ray scattering
We measured high resolution Cu edge resonant inelastic x-ray scattering
(RIXS) of the undoped cuprates LaCuO, SrCuOCl, CaCuO
and NdBaCuO. The dominant spectral features were assigned to
excitations and we extensively studied their polarization and scattering
geometry dependence. In a pure ionic picture, we calculated the theoretical
cross sections for those excitations and used them to fit the experimental data
with excellent agreement. By doing so, we were able to determine the energy and
symmetry of Cu-3 states for the four systems with unprecedented accuracy and
confidence. The values of the effective parameters could be obtained for the
single ion crystal field model but not for a simple two-dimensional cluster
model. The firm experimental assessment of excitation energies carries
important consequences for the physics of high superconductors. On one
hand, having found that the minimum energy of orbital excitation is always
eV, i.e., well above the mid-infrared spectral range, leaves to
magnetic excitations (up to 300 meV) a major role in Cooper pairing in
cuprates. On the other hand, it has become possible to study quantitatively the
effective influence of excitations on the superconducting gap in cuprates.Comment: 22 pages, 11 figures, 1 tabl
Foreign policy beliefs and support for Stephen Harper and the Conservative Party
Similar to other recent Canadian elections, foreign policy did not feature prominently in the 2011 federal election campaign. In fact, many doubt Canadian public opinion on international affairs is linked to the actions taken by recent Governments. In this paper, we examine Canadian public opinion toward a range of foreign policy issues and argue that the survey questions measure two latent dimensions âmilitarism and internationalism. Our survey evidence indicates the existence of an âissue publicâ which is prepared to endorse military action and is skeptical of human rights and overseas aid programs, and this group is far more supportive of Prime Minister Harper and the Conservative Party than other Canadians. The absence of an elite discussion, either among politicians or between media elites, about the direction of Canadian foreign policy does not prevent the Canadian voter from thinking coherently about questions pertaining to this issue domain and employing these beliefs to support or oppose political parties and their leaders
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Adiposity and systolic blood pressure
OBJECTIVES: The positive association between adiposity and hypertension is well recognized. However, not all overweight individuals have elevated blood pressure (BP). Moreover, different factors may be associated with high BP in normal-weight versus overweight individuals. The aim of the current study was to examine the influence of adiposity on the relationship between SBP and underlying haemodynamic mechanisms in young adults. METHOD: Data from 2502 patients were available from the Enigma study. Detailed demographic, biochemical, and haemodynamic data were obtained in all individuals. Data were analysed between lower and upper tertiles of BMI and SBP, separately for each sex. RESULTS: In normal-weight individuals, cardiac output (CO) was elevated in those with higher SBP, independently of body size. Moreover, higher CO was associated with an increased stroke volume in men (Pâ<â0.001), but an increased heart rate in women (Pâ=â0.002). In contrast, in overweight individuals, peripheral vascular resistance (PVR) was elevated in men with higher SBP (Pâ=â0.02) and those with lower SBP had the lowest PVR of all groups. In linear regression analyses, there was a stronger association between SBP and CO in normal-weight individuals, but a stronger association between SBP and PVR in overweight individuals. CONCLUSION: Different haemodynamic mechanisms are associated with elevated SBP in young adults, depending on body size and sex. These data suggest the need for differential approaches to the identification and management of young adults with elevated BP.This work was funded by the British Heart Foundation and the NIHR Cambridge Biomedical Research CentreThis is the final version of the article. It was first available from Lippincott Williams & Wilkins via http://dx.doi.org/10.1097/HJH.000000000000079
High-Resolution Solid-State Oxygen-17 NMR of Actinide-Bearing Compounds: An Insight into the 5f Chemistry
Palliative and end-of-life care research in Scotland 2006-2015: A systematic scoping review
Background:
The Scottish Government set out its 5-year vision to improve palliative care in its Strategic Framework for Action 2016â2021. This includes a commitment to strengthening research and evidence based knowledge exchange across Scotland. A comprehensive scoping review of Scottish palliative care research was considered an important first step. The aim of the review was to quantify and map palliative care research in Scotland over the ten-year period preceding the new strategy (2006â15).
Methods:
A systematic scoping review was undertaken. Palliative care research involving at least one co-author from a Scottish institution was eligible for inclusion. Five databases were searched with relevant MeSH terms and keywords; additional papers authored by members of the Scottish Palliative and End of Life Care Research Forum were added.
Results:
In total, 1919 papers were screened, 496 underwent full text review and 308 were retained in the final set. 73% were descriptive studies and 10% were interventions or feasibility studies. The top three areas of research focus were services and settings; experiences and/or needs; and physical symptoms. 58 papers were concerned with palliative care for people with conditions other than cancer â nearly one fifth of all papers published. Few studies focused on ehealth, health economics, out-of-hours and public health. Nearly half of all papers described unfunded research or did not acknowledge a funder (46%).
Conclusions:
There was a steady increase in Scottish palliative care research during the decade under review. Research output was strong compared with that reported in an earlier Scottish review (1990â2005) and a similar review of Irish palliative care research (2002â2012). A large amount of descriptive evidence exists on living and dying with chronic progressive illness in Scotland; intervention studies now need to be prioritised. Areas highlighted for future research include palliative interventions for people with non-malignant illness and multi-morbidity; physical and psychological symptom assessment and management; interventions to support carers; and bereavement support. Knowledge exchange activities are required to disseminate research findings to research users and a follow-up review to examine future research progress is recommended
Proteomics of a toxic dinoflagellate Alexandrium catenella DH01: Detection and identification of cell surface proteins using fluorescent labeling
The Core Value Compass: visually evaluating the goodness of brands that do good
yesBrands that do good for the society as well as for
themselves are motivated by the core values they espouse,
which necessitates a better understanding of what qualities a
true core value must possess. The inherent tension within
brands that do good, between commercial interests to
increase competitiveness, and societal interests that are
closely linked to the brandâs authenticity, has largely been
overlooked. Hence, we develop and demonstrate a relatively
easy-to-apply visual tool for evaluating core values based on
a set of âgoodnessâ criteria derived from extant theory. The
Core Value Compass adopts a paradox-based, evolutionary
perspective by incorporating the inherent tensions within
true core values, and classifying them according to their
temporal orientation. Thus, we contribute towards a better
understanding of underlying tensions of core values and
provide a practical tool that paves the way for improved, and
indeed ethical, corporate branding strategies. Furthermore,
we demonstrate the Compassâ application using the case of a
public sector brand, which is a quintessential brand that does
good. Therefore, we also contribute to the nascent theoretical
discourse on public sector branding. This paper therefore
adds to the notable attempts to bridge the gap between theory
and practice in core values-based corporate branding
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Reply.
We agree with many of the points made by Lurbe and Redon,1 which were similar to those raised in our own article. Certainly, the ability to assess central blood pressure (BP) noninvasively has increased our understanding of isolated systolic hypertension (ISH) in young people. However, rather than providing any mechanistic information, assessment of central BP simply highlights that ISH in young people cannot be attributed to exaggerated amplification of a normal central BP, but, instead, is associated with elevated central and brachial systolic BP. In this regard, measurements of cardiac output and stroke volume are more informative and could, potentially, be used to stratify risk in young individuals in the future
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