10 research outputs found
Fathers of Four Male Children With Primary Conduct Disorders: A Casework Study of Four Fathers, Whose Sons Indicate a Primary Disturbance in Conduct, Serviced at Catholic Charities Guidance Institute
Fathers play an important role in the lives of their children. Practitioners working with patients who indicate behavioral difficulties and personality maladjustments are gradually becoming more aware of the importance and impact of the father-child relationship, and the ramifications resulting from this relationship. More research is needed in this area and it is hoped that this project would augment, however slight, the knowledge that has been gained through research and study up to the present time
Free Edges in Epithelial Cell Sheets Stimulate Epidermal Growth Factor Receptor Signaling
Epithelia tend to migrate when edges are present, for instance, after wounding or during development. Using a new tissue culture model, we found that the existence of free edges is in itself a signal that causes activation of the epidermal growth factor and cell motility
Interactome of Two Diverse RNA Granules Links mRNA Localization to Translational Repression in Neurons
Transport of RNAs to dendrites occurs in neuronal RNA granules, which allows local synthesis of specific proteins at active synapses on demand, thereby contributing to learning and memory. To gain insight into the machinery controlling dendritic mRNA localization and translation, we established a stringent protocol to biochemically purify RNA granules from rat brain. Here, we identified a specific set of interactors for two RNA-binding proteins that are known components of neuronal RNA granules, Barentsz and Staufen2. First, neuronal RNA granules are much more heterogeneous than previously anticipated, sharing only a third of the identified proteins. Second, dendritically localized mRNAs, e.g., Arc and CaMKIIα, associate selectively with distinct RNA granules. Third, our work identifies a series of factors with known roles in RNA localization, translational control, and RNA quality control that are likely to keep localized transcripts in a translationally repressed state, often in distinct types of RNPs
Multiple residues in the distal C terminus of the α-subunit have roles in modulating human epithelial sodium channel activity
Brief treatment with heparin-binding EGF-like growth factor, but not with EGF, is sufficient to accelerate epithelial wound healing
Navidades de Madrid y noches entretenidas: edición digital de seis novelas
Una edición digital anotada de seis novelas procedentes de la colección de Mariana de Carvajal y Saavedra, Navidades de Madrid y noches entretenidas (1663), preparada por los estudiantes de la clase SPAN 365: Escritoras y su empoderamiento en la literatura del Siglo de Oro (Gettysburg College, primavera de 2021)
English: A digital annotated edition of six novels from Mariana de Carvajal y Saavedra’s collection Navidades de Madrid y noches entretenidas (1663), prepared by students in SPAN 365: Female Authors and Empowerment in Spain’s Golden Age (Gettysburg College, Spring 2021)https://cupola.gettysburg.edu/oer/1008/thumbnail.jp