371 research outputs found
Sovereign Liability for Defective or Dangerous Plan or Design--California Government Code Section 830.6
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X-ray Insights into the Nature of Weak Emission-Line Quasars at High Redshift
We present Chandra observations of nine high-redshift quasars (z=2.7-5.9)
discovered by the Sloan Digital Sky Survey with weak or undetectable
high-ionization emission lines in their UV spectra (WLQs). Adding archival
X-ray observations of six additional sources of this class has enabled us to
place the strongest constraints yet on the X-ray properties of this remarkable
class of AGNs. Although our data cannot rule out the possibility that the
emission lines are overwhelmed by a relativistically boosted continuum, as
manifested by BL Lac objects, we find that WLQs are considerably weaker in the
X-ray and radio bands than the majority of BL Lacs found at much lower
redshifts. If WLQs are high-redshift BL Lacs, then it is difficult to explain
the lack of a large parent population of X-ray and radio bright weak-lined
sources at high redshift. We also consider the possibility that WLQs are
quasars with extreme properties, and in particular that the emission lines are
suppressed by high accretion rates. Using joint spectral fitting of the X-ray
spectra of 11 WLQs we find that the mean photon index in the hard X-ray band is
consistent with those observed in typical radio-quiet AGNs with no hint of an
unusually steep hard-X-ray spectrum. This result poses a challenge to the
hypothesis that WLQs have extremely high accretion rates, and we discuss
additional observations required to test this idea.Comment: 13 pages (emulateapj), 7 figures. Accepted for publication in Ap
Genetic Variation in the Population of Ibiza (Spain): Genetic Structure, Geography, and Language
This is the published version, also available here: http://www.jstor.org/stable/41465529
Heritability of anthropometric phenotypes in caste populations of Visakhapatnam, India
This is the publisher's version, also available electronically from http://digitalcommons.wayne.edu/humbiol/vol74/iss3/1/.In this study, we used anthropometric data from six Andhra caste populations to examine heritability patterns of 23 anthropometric phenotypes (linear, craniofacial, and soft tissue measures) with special reference to caste differences. We obtained anthropometric data from 342 nuclear families from Brahmin, Reddy, Telaga, Nagara, Ag. Kshatriya, and Mala castes of Visakhapatnam, India. These caste groups represent the existing hierarchical stratification of Indian populations. We used a variance components approach to determine the heritability (h2) of these 23 anthropometric phenotypes (height, weight, BMI, etc.). The sample consisted of 1918 individuals ranging in age from 6 to 72 years (mean = 21.5, S.D. = 13.8). The heritabilities (h2 ± S.E.) for all anthropometric traits for the entire sample were significant (p < 0.0001) and varied from 0.25 ± 0.05 (BMI) to 0.61 ± 0.05 (bizygomatic breadth) after accounting for sex, age, and caste effects. Since data on socioeconomic and nutritional covariates were available for a subset of families, we repeated the genetic analyses using this subset, which has yielded higher heritabilities ranging from 0.21 ± 0.16 (head breadth) to 0.72 ± 0.18 (nasal breadth). In general, craniofacial measurements exhibited higher h2 compared to linear measures. Breadth measurements and circumferences yielded more or less similar heritabilities. Age and sex effects were significant (p < 0.0001) for most of the traits, while the effects of caste, socioeconomic status, and nutritional status were inconsistent across the traits. In conclusion, anthropometric phenotypes examined in this study are under appreciable additive genetic influences
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Reverse time migration in tilted transversely isotropic media
This paper presents a reverse time migration (RTM) method for the migration of shot records in tilted transversely isotropic (TTI) media. It is based on the tilted TI acoustic wave equation that was derived from the dispersion relation. The RTM is a full depth migration allowing for velocity to vary laterally as well as vertically and has no dip limitations. The wave equation is solved by a tenth-order finite difference scheme. Using 2D numerical models, we demonstrate that ignoring the tilt angle will introduce both lateral and vertical shifts in imaging. The shifts can be larger than 0.5 wavelength in the vertical direction and 1.5 wavelength in the lateral direction
Examining Social Vulnerability and the association With Covid-19 incidence in Harris County, Texas
Studies have investigated the association between social vulnerability and SARS-CoV-2 incidence. However, few studies have examined small geographic units such as census tracts, examined geographic regions with large numbers of Hispanic and Black populations, controlled for testing rates, and incorporated stay-at-home measures into their analyses. Understanding the relationship between social vulnerability and SARS-CoV-2 incidence is critical to understanding the interplay between social determinants and implementing risk mitigation guidelines to curtail the spread of infectious diseases. The objective of this study was to examine the relationship between CDC\u27s Social Vulnerability Index (SVI) and SARS-CoV-2 incidence while controlling for testing rates and the proportion of those who stayed completely at home among 783 Harris County, Texas census tracts. SARS-CoV-2 incidence data were collected between May 15 and October 1, 2020. The SVI and its themes were the primary exposures. Median percent time at home was used as a covariate to measure the effect of staying at home on the association between social vulnerability and SARS-CoV-2 incidence. Data were analyzed using Kruskal Wallis and negative binomial regressions (NBR) controlling for testing rates and staying at home. Results showed that a unit increase in the SVI score and the SVI themes were associated with significant increases in SARS-CoV-2 incidence. The incidence risk ratio (IRR) was 1.090 (95% CI, 1.082, 1.098) for the overall SVI; 1.107 (95% CI, 1.098, 1.115) for minority status/language; 1.090 (95% CI, 1.083, 1.098) for socioeconomic; 1.060 (95% CI, 1.050, 1.071) for household composition/disability, and 1.057 (95% CI, 1.047, 1.066) for housing type/transportation. When controlling for stay-at-home, the association between SVI themes and SARS-CoV-2 incidence remained significant. In the NBR model that included all four SVI themes, only the socioeconomic and minority status/language themes remained significantly associated with SARS-CoV-2 incidence. Community-level infections were not explained by a communities\u27 inability to stay at home. These findings suggest that community-level social vulnerability, such as socioeconomic status, language barriers, use of public transportation, and housing density may play a role in the risk of SARS-CoV-2 infection regardless of the ability of some communities to stay at home because of the need to work or other reasons
Identifying Sensitive Windows of Exposure to NO2 and Fetal Growth Trajectories in a Spanish Birth Cohort
Background: We previously identified associations between trimester-specific NO2 exposures and reduced fetal growth in the Spanish INfancia y Medio Ambiente (INMA) project. Here, we use temporally refined exposure estimates to explore the impact of narrow (weekly) windows of exposure on fetal growth. Methods: We included 1,685 women from INMA with serial ultrasounds at 12, 20, and 34 gestational weeks. We measured biparietal diameter (BPD), femur length, and abdominal circumference (AC) and from them calculated estimated fetal weight (EFW). We calculated z-scores describing trajectories of each parameter during early (0-12 weeks), mid (12-20 weeks), and late (20-34 weeks) pregnancy, based on longitudinal growth curves from mixed-effects models. We estimated weekly NO2 exposures at each woman's residence using land-use regression models. We applied distributed lag nonlinear models to identify sensitive windows of exposure. We present effect estimates as the percentage change in fetal growth per 10 mu g/m(3) increase in NO2 exposure, and we calculated cumulative effect estimates by aggregating estimates across adjacent lags. Results: We identified weeks 5-12 as a sensitive window for NO2 exposure on late EFW (cumulative beta = -3.0%; 95% CI = -4.1%, -1.9%). We identified weeks 6-19 as a sensitive window for late growth in BPD (cumulative beta = -2.0%; 95% CI = -2.7%, -1.4%) and weeks 8-13 for AC (cumulative beta = -0.68%; 95% CI = -0.97%, -0.40%). We found suggestive evidence that third trimester NO2 exposure is associated with increased AC, BPD, and EFW growth in late pregnancy. Conclusions: Our findings are consistent with the hypothesis that NO2 exposure is associated with alterations in growth of EFW, BPD, and AC dependent on the specific timing of exposure during gestation.K.W.W. and E.S. were partially supported by the P30 Environmental Health Sciences Core Center grant P30ES030285 from the National Institute
Operations in the homology spectral sequence of a cosimplicial infinite loop space
Consider the mod 2 homology spectral sequence associated to a cosimplicial
space X. We construct external operations whose target is the spectral sequence
associated to E\Sigma_2 \times_{\Sigma_2} (X\times X). If X is a cosimplicial
E_\infty-space, we couple these external operations with the structure map
E\Sigma_2 \times_{\Sigma_2} (X\times X) \to X to produce internal operations in
the spectral sequence. In the sequel we show that they agree with the usual
Araki-Kudo operations on the abutment H_*(Tot X).Comment: final versio
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