1,662 research outputs found

    Developing a Research Culture and Scholarship Plan in Information Studies

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    Information research may take many forms. When the researchers are situated within an information technology faculty, there is a natural orientation towards the technology and the systems that make possible the use of the technology. Despite this, a focus on information itself and its effective utilisation can be achieved in an environment that may otherwise be more concerned with the technology than the information that the technology carries. This focus can contribute to research that has a systems orientation, as well as both foster and be fostered by interdisciplinary work in areas such as education, management and psychology. Here we explain the development of a research program in ‘information use’ within the Socio-technical systems theme of the School of Information Systems at QUT. Our emphasis is on the processes – research supervision, industry linkage, consultancy, grant development, conference contribution and publication - that have advanced the development of the research group. We also provide a summary of research projects in the form of models that are being developed to help illuminate the research frameworks

    Changes in Behavior, Movement, and Home Ranges of Largemouth Bass Following Large-scale Hydrilla Removal in Lake Seminole, Georgia

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    About 1,200 ha of hydrilla ( Hydrilla verticillata L.f. Royle) was eliminated in the Spring Creek embayment of Lake Seminole, Georgia, using a drip-delivery application of fluridone (1- methyl-3-phenyl-5-[3-(trifluoromethl) phenyl]-4(1H)-pyridinone) in 2000 and 2001. Two groups of 15 and 20 largemouth bass (Micropterus salmoides Lacepede) were implanted with 400-day radio tags in February 2000 and 2001 to determine changes in movement and behavior before and after hydrilla reduction.(PDF contains 8 pages.

    Reevaluation of the Impact of Coal Mining on the Virginia State Budge

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    Downstream Strategies, an environmental consulting and policy analysis firm, published The Impact of Coal on the Virginia State Budget in 2012, finding that the coal mining industry was responsible for a net cost of 21.9 million USD to the Commonwealth in 2009 (considering only the Virginia General Assembly's General Fund and Transportation Fund revenues and expenditures). We provide a reanalysis of the same topic, considering the effect the presence of the coal industry has on the entire state budget that is not limited to the General Fund. We estimate that in our study year of 2011, the coal industry contributed 31.95 million USD in taxes and fees to the state while the Commonwealth's expenditures relating to the coal industry totaled 24.4 million USD. However, firms producing coal in Virginia also benefit from two exclusive refundable tax credits which we estimate combine to 49.37 million USD. We find that the coal industry was associated with a net cost of 36.7 million USD to the Virginia state budget in 2011

    Zero Temperature Thermodynamics of Asymmetric Fermi Gases at Unitarity

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    The equation of state of a dilute two-component asymmetric Fermi gas at unitarity is subject to strong constraints, which affect the spatial density profiles in atomic traps. These constraints require the existence of at least one non-trivial partially polarized (asymmetric) phase. We determine the relation between the structure of the spatial density profiles and the T=0 equation of state, based on the most accurate theoretical predictions available. We also show how the equation of state can be determined from experimental observations.Comment: 10 pages and 7 figures. (Minor changes to correspond with published version.

    Taking Measure of Ohio's Opioid Crisis

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    Opioid addiction, abuse, and overdose deaths have become the most pressing public health issue facing Ohio. Ohio leads the country in drug overdose deaths per capita, a rate that continues to rise, overwhelming families, communities, and local governments across the state. In this policy brief, we aim to contribute to the understanding of this unfolding crisis and highlight insights that can inform policymaking

    Passive and catalytic antibodies and drug delivery

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    Antibodies are one of the most promising components of the biotechnology repertoire for the purpose of drug delivery. On the one hand, they are proven agents for cell-selective delivery of highly toxic agents in a small but expanding number of cases. This technology calls for the covalent attachment of the cytotoxin to a tumor-specific antibody by a linkage that is reversible under appropriate conditions (antibody conjugate therapy, ACT —"passive delivery”). On the other hand, the linker cleavage can be accomplished by a protein catalyst attached to the tumor-specific antibody ("catalytic delivery”). Where the catalyst is an enzyme, this approach is known as antibody-directed enzyme prodrug therapy (ADEPT). Where the transformation is brought about by a catalytic antibody, it has been termed antibody-directed abzyme prodrug therapy (ADAPT). These approaches will be illustrated with emphasis on how their demand for new biotechnology is being realized by structure-based protein engineerin

    The Atacama Cosmology Telescope: Sunyaev-Zel'dovich Selected Galaxy Clusters at 148 GHz from Three Seasons of Data

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    [Abridged] We present a catalog of 68 galaxy clusters, of which 19 are new discoveries, detected via the Sunyaev-Zel'dovich effect (SZ) at 148 GHz in the Atacama Cosmology Telescope (ACT) survey of 504 square degrees on the celestial equator. A subsample of 48 clusters within the 270 square degree region overlapping SDSS Stripe 82 is estimated to be 90% complete for M_500c > 4.5e14 Msun and 0.15 < z < 0.8. While matched filters are used to detect the clusters, the sample is studied further through a "Profile Based Amplitude Analysis" using a single filter at a fixed \theta_500 = 5.9' angular scale. This new approach takes advantage of the "Universal Pressure Profile" (UPP) to fix the relationship between the cluster characteristic size (R_500) and the integrated Compton parameter (Y_500). The UPP scalings are found to be nearly identical to an adiabatic model, while a model incorporating non-thermal pressure better matches dynamical mass measurements and masses from the South Pole Telescope. A high signal to noise ratio subsample of 15 ACT clusters is used to obtain cosmological constraints. We first confirm that constraints from SZ data are limited by uncertainty in the scaling relation parameters rather than sample size or measurement uncertainty. We next add in seven clusters from the ACT Southern survey, including their dynamical mass measurements based on galaxy velocity dispersions. In combination with WMAP7 these data simultaneously constrain the scaling relation and cosmological parameters, yielding \sigma_8 = 0.829 \pm 0.024 and \Omega_m = 0.292 \pm 0.025. The results include marginalization over a 15% bias in dynamical mass relative to the true halo mass. In an extension to LCDM that incorporates non-zero neutrino mass density, we combine our data with WMAP7+BAO+Hubble constant measurements to constrain \Sigma m_\nu < 0.29 eV (95% C. L.).Comment: 32 pages, 21 figures To appear in J. Cosmology and Astroparticle Physic

    The Atacama Cosmology Telescope: Cross Correlation with Planck maps

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    We present the temperature power spectrum of the Cosmic Microwave Background obtained by cross-correlating maps from the Atacama Cosmology Telescope (ACT) at 148 and 218 GHz with maps from the Planck satellite at 143 and 217 GHz, in two overlapping regions covering 592 square degrees. We find excellent agreement between the two datasets at both frequencies, quantified using the variance of the residuals between the ACT power spectra and the ACTxPlanck cross-spectra. We use these cross-correlations to calibrate the ACT data at 148 and 218 GHz, to 0.7% and 2% precision respectively. We find no evidence for anisotropy in the calibration parameter. We compare the Planck 353 GHz power spectrum with the measured amplitudes of dust and cosmic infrared background (CIB) of ACT data at 148 and 218 GHz. We also compare planet and point source measurements from the two experiments.Comment: 9 pages, 8 figure
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