7 research outputs found

    Perceptions of Secondary School Students towards Natural Resources Management: Case Study of Participants in FoF and Non-Participants

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    Integrating natural resources management in the secondary school curriculum in Kenya has received a lot of talk without adequate practical activities. The Farmers of the Future Programme under the World Agroforestry Centre, formally the International Centre for Research in Agroforestry (ICRAF), initiated a practical approach to integration of natural resources management in the secondary school curriculum in Kenya. This paper provides information on significant findings of a study that was carried out to determine the potential of FoF in integrating natural resources management into the secondary school curriculum in Kenya. A comparison between secondary school students who are involved in FoF programme and those not involved was done to determine their perceptions towards natural resources management. Further, comparison of perceptions by gender among learners who are involved in the FoF initiative was done. The study employed an ex-post-facto design in data collection using questionnaires. Questionnaires and were analysed using t-test at alpha = 0.05. The findings indicated that the FoF programme had a significant influence on learners’ perceptions towards natural resources management. It was therefore concluded that FoF programme enhanced positive perceptions towards natural resources management among learners. On the basis of the findings, it was recommended that the FoF programme be expanded to cover more schools

    Integration of Natural Resource Management in the Primary Education Curriculum in Kenya

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    The Farmers of the Future (FoF) initiative implemented a programme of integrating natural resources management in the basic education curriculum. The purpose of the study was to document activities and determine the effects of FoF programme on primary school learners’ perceptions towards natural resources management by comparing learners involved in the FoF programme and those not involved. Further, comparison of perceptions by gender among learners involved in the FoF was done. The study employed an ex-post-facto design. The location of the study was the western region of Kenya. The sample was composed of 120 learners and 6 teachers, making a total of 126 respondents. This was in accordance with recommendations by Kathuri and Pals (1993). The data were collected using questionnaires and analysed using t-test at alpha = 0.05. The instruments were validated by two experts in the Department of Agricultural Education and Extension at Egerton University and one expert from ICRAF. Reliability was tested through pilot testing and indicated a reliability coefficient of 0.72 The findings indicated that the FoF programme had a significant influence on learners’ positive perceptions towards natural resources management thus the programme forms an integral part in sustainable agriculture

    Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study

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    Background: Human genetic factors are important determinants of malaria risk. We investigated associations between multiple candidate polymorphisms—many related to the structure or function of red blood cells—and risk for severe Plasmodium falciparum malaria and its specific phenotypes, including cerebral malaria, severe malaria anaemia, and respiratory distress. Methods: We did a case-control study in Kilifi County, Kenya. We recruited as cases children presenting with severe malaria to the high-dependency ward of Kilifi County Hospital. We included as controls infants born in the local community between Aug 1, 2006, and Sept 30, 2010, who were part of a genetics study. We tested for associations between a range of candidate malaria-protective genes and risk for severe malaria and its specific phenotypes. We used a permutation approach to account for multiple comparisons between polymorphisms and severe malaria. We judged p values less than 0·005 significant for the primary analysis of the association between candidate genes and severe malaria. Findings: Between June 11, 1995, and June 12, 2008, 2244 children with severe malaria were recruited to the study, and 3949 infants were included as controls. Overall, 263 (12%) of 2244 children with severe malaria died in hospital, including 196 (16%) of 1233 with cerebral malaria. We investigated 121 polymorphisms in 70 candidate severe malaria-associated genes. We found significant associations between risk for severe malaria overall and polymorphisms in 15 genes or locations, of which most were related to red blood cells: ABO, ATP2B4, ARL14, CD40LG, FREM3, INPP4B, G6PD, HBA (both HBA1 and HBA2), HBB, IL10, LPHN2 (also known as ADGRL2), LOC727982, RPS6KL1, CAND1, and GNAS. Combined, these genetic associations accounted for 5·2% of the variance in risk for developing severe malaria among individuals in the general population. We confirmed established associations between severe malaria and sickle-cell trait (odds ratio [OR] 0·15, 95% CI 0·11–0·20; p=2·61 × 10−58), blood group O (0·74, 0·66–0·82; p=6·26 × 10−8), and –α3·7-thalassaemia (0·83, 0·76–0·90; p=2·06 × 10−6). We also found strong associations between overall risk of severe malaria and polymorphisms in both ATP2B4 (OR 0·76, 95% CI 0·63–0·92; p=0·001) and FREM3 (0·64, 0·53–0·79; p=3·18 × 10−14). The association with FREM3 could be accounted for by linkage disequilibrium with a complex structural mutation within the glycophorin gene region (comprising GYPA, GYPB, and GYPE) that encodes for the rare Dantu blood group antigen. Heterozygosity for Dantu was associated with risk for severe malaria (OR 0·57, 95% CI 0·49–0·68; p=3·22 × 10−11), as was homozygosity (0·26, 0·11–0·62; p=0·002). Interpretation: Both ATP2B4 and the Dantu blood group antigen are associated with the structure and function of red blood cells. ATP2B4 codes for plasma membrane calcium-transporting ATPase 4 (the major calcium pump on red blood cells) and the glycophorins are ligands for parasites to invade red blood cells. Future work should aim at uncovering the mechanisms by which these polymorphisms can result in severe malaria protection and investigate the implications of these associations for wider health. Funding: Wellcome Trust, UK Medical Research Council, European Union, and Foundation for the National Institutes of Health as part of the Bill & Melinda Gates Grand Challenges in Global Health Initiative
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