3,810 research outputs found

    Properties of a Polar Coronal Hole During the Solar Minimum in 2007

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    We report measurements of a polar coronal hole during the recent solar minimum using the Extreme Ultraviolet Imaging Spectrometer on Hinode. Five observations are analyzed that span the polar coronal hole from the central meridian to the boundary with the quiet-Sun corona. We study the observations above the solar limb in the height range of 1.03-1.20 R ☉. The electron temperature T e and emission measure (EM) are found using a geometric mean emission measure method. The EM derived from the elements Fe, Si, S, and Al are compared in order to measure relative coronal-to-photospheric abundance enhancement factors. We also studied the ion temperature T i and the non-thermal velocity v nt using the line profiles. All these measurements are compared to polar coronal hole observations from the previous (1996-1997) solar minimum and to model predictions for relative abundances. There are many similarities in the physical properties of the polar coronal holes between the two minima at these low heights. We find that the electron density, T e, and T i are comparable in both minima. T e shows a comparable gradient with height. Both minima show a decreasing T i with increasing charge-to-mass ratio q/M. A previously observed upturn of T i for ions above q/M>0.25 was not found here. We also compared relative coronal-to-photospheric elemental abundance enhancement factors for a number of elements. These ratios were ~1 for both the low first ionization potential (FIP) elements Si and Al and the marginally high FIP element S relative to the low FIP element Fe, as is expected based on earlier observations and models for a polar coronal hole. These results are consistent with no FIP effect in a polar coronal hole

    Light-induced nuclear export reveals rapid dynamics of epigenetic modifications

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    We engineered a photoactivatable system for rapidly and reversibly exporting proteins from the nucleus by embedding a nuclear export signal in the LOV2 domain from phototropin 1. Fusing the chromatin modifier Bre1 to the photoswitch, we achieved light-dependent control of histone H2B monoubiquitylation in yeast, revealing fast turnover of the ubiquitin mark. Moreover, this inducible system allowed us to dynamically monitor the status of epigenetic modifications dependent on H2B ubiquitylation

    The Design and Development of an Integrated Researcher Profile System at Texas A&M to Enrich Scholarly Identity of Faculty.

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    Researcher profile systems (RPS) are web-based tools to discover and use research and scholarly information about people and resources. These systems serve as knowledge management systems for the research enterprise as they connect institution-level/enterprise systems, national research networks, publicly available research data (e.g., grants and publications), and restricted/proprietary data by harvesting information from disparate sources into compiled expertise profiles for faculty, investigators, scholars, clinicians, community partners, and facilities. RPS tools facilitate the development of new collaborations and team science to address new or existing research challenges through the rapid discovery and recommendation of researchers, expertise, and resources. In addition, data harvested into an RPS is accessible for broad repurposing, especially if available as linked open data (RDF triples). Thus RPS can enhance research support activities by providing data for customized, up-to-date web pages, CV/biosketch generation, and data tables for grant proposals as well as serve the needs of an academic organization. In 2014, the library started experimenting with VIVO, an open source, semantic researcher profile system available through Duraspace. VIVO is an open source semantic web application originally developed and implemented at Cornell. When installed and populated with researcher interests, activities, and accomplishments, it enables the discovery of research and scholarship across disciplines at that institution and beyond. VIVO supports browsing and a search function that returns faceted results for rapid retrieval of desired information. Content in any local VIVO installation may be maintained manually, brought into VIVO in automated ways from local systems of record, such as HR, grants, course, and faculty activity databases, or from database providers such as publication aggregators and funding agencies. As our project continued, we worked on integrating several other tools to create a more useful and compelling system that meets the needs of a range of campus stakeholders. Our integrated system includes: VIVO: aggregator of faculty profiles supporting the discovery of expertise and the reuse of profile data. PLUMX: Plum Analytics is a tool that provides insight into scholarly reputation. Plum™ Analytics measures metrics for individual research artifacts and aggregates the data labs, departments and other meaningful groups. The tool collects impact metrics in 5 major categories: usage, captures, mentions, social media, and citations. Plum Analytics tracks more than 20 different types of artifacts, including journal articles, books, videos, presentations, conference proceedings, datasets, source code, cases, and more. ORCIDs: a third-party, not for profit organization that provides a platform for the assignment of unique researchers ID numbers. The primary purpose of ORCID is to provide an authoritative way to differentiate authors with similar names and to unify works by the same author published under different names (e.g., maiden and married names, transliterated names. Publication and Data Repositories: OAKTrust, TDL data repository, PubMed, etc. Symplectic Elements: Third-party support for faculty profile data harvesting. This presentation will cover the use cases identified at Texas A&M, the technical development of our integrated researcher profile system, and our process in working with the Texas A&M community

    Quantitative diffusion tensor imaging detects dopaminergic neuronal degeneration in a murine model of Parkinson\u27s disease.

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    Early diagnosis of Parkinson\u27s disease (PD) is required to improve therapeutic responses. Indeed, a clinical diagnosis of resting tremor, rigidity, movement and postural deficiencies usually reflect \u3e50% loss of the nigrostriatal system in disease. In a step to address this, quantitative diffusion tensor magnetic resonance imaging (DTI) was used to assess nigrostriatal degeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) intoxication model of dopaminergic nigral degeneration. We now demonstrate increased average diffusion (p\u3c0.005) and decreased fractional anisotropy (p\u3c0.03) in the substantia nigra (SN) of 5- to 7-day MPTP-treated animals when compared to saline controls. Transverse diffusivity demonstrated the most significant differences (p \u3c or = 0.002) and correlated with the numbers of SN dopaminergic neurons (r=-0.75, p=0.012). No differences were found in the striatum, corpus callosum, cerebral cortex, or ventricles. These results demonstrate that DTI may be used as a surrogate biomarker of nigral dopaminergic neuronal degeneration

    Optimizing phosphorus diffusion for photovoltaic applications: Peak doping, inactive phosphorus, gettering, and contact formation

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    The phosphosilicate glass (PSG), fabricated by tube furnace diffusion using a POCl3 source, is widely used as a dopant source in the manufacturing of crystalline silicon solar cells. Although it has been a widely addressed research topic for a long time, there is still lack of a comprehensive understanding of aspects such as the growth, the chemical composition, possible phosphorus depletion, the resulting in-diffused phosphorus profiles, the gettering behavior in silicon, and finally the metal-contact formation. This paper addresses these different aspects simultaneously to further optimize process conditions for photovoltaic applications. To do so, a wide range of experimental data is used and combined with device and process simulations, leading to a more comprehensive interpretation. The results show that slight changes in the PSG process conditions can produce high-quality emitters. It is predicted that PSG processes at 860?°C for 60?min in combination with an etch-back and laser doping from PSG layer results in high-quality emitters with a peak dopant density Npeak?=?8.0?×?1018?cm?3 and a junction depth dj?=?0.4?m, resulting in a sheet resistivity?sh?=?380 ?/sq and a saturation current-density J0 below 10 fA/cm2. With these properties, the POCl3 process can compete with ion implantation or doped oxide approaches

    The Promise of Prediction Markets

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    Prediction markets are markets for contracts that yield payments based on the outcome of an uncertain future event, such as a presidential election. Using these markets as forecasting tools could substantially improve decision making in the private and public sectors. We argue that U.S. regulators should lower barriers to the creation and design of prediction markets by creating a safe harbor for certain types of small stakes markets. We believe our proposed change has the potential to stimulate innovation in the design and use of prediction markets throughout the economy, and in the process to provide information that will benefit the private sector and government alike.Technology and Industry
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