1,470 research outputs found
MARKET FORCES AND CHANGES IN THE PLANT INPUT SUPPLY INDUSTRY
Agribusiness, Input Supply Industry, Fertilizer, Plant Nutrients, Seed, Capital, Market Forces, Structural Change, Porter’s Five Forces, Agribusiness, Q13, L10, L22, M22, L80,
Physics Opportunities with Meson Beams
Over the past two decades, meson photo- and electro-production data of
unprecedented quality and quantity have been measured at electromagnetic
facilities worldwide. By contrast, the meson-beam data for the same hadronic
final states are mostly outdated and largely of poor quality, or even
nonexistent, and thus provide inadequate input to help interpret, analyze, and
exploit the full potential of the new electromagnetic data. To reap the full
benefit of the high-precision electromagnetic data, new high-statistics data
from measurements with meson beams, with good angle and energy coverage for a
wide range of reactions, are critically needed to advance our knowledge in
baryon and meson spectroscopy and other related areas of hadron physics. To
address this situation, a state of-the-art meson-beam facility needs to be
constructed. The present paper summarizes unresolved issues in hadron physics
and outlines the vast opportunities and advances that only become possible with
such a facility.Comment: 46 pages, 10 figures, 4 table
BB Intermeson Potentials in the Quark Model
In this paper we derive quark model results for scattering amplitudes and
equivalent low energy potentials for heavy meson pairs, in which each meson
contains a heavy quark. This "BB" system is an attractive theoretical
laboratory for the study of the nuclear force between color singlets; the
hadronic system is relatively simple, and there are lattice gauge theory (LGT)
results for V_BB(r) which may be compared to phenomenological models. We find
that the quark model potential (after lattice smearing) has qualitative
similarities to the LGT potential in the two B*B* channels in which direct
comparison is possible, although there is evidence of a difference in length
scales. The quark model prediction of equal magnitude but opposite sign for I=0
and I=1 potentials also appears similar to LGT results at intermediate r. There
may however be a discrepancy between the LGT and quark model I=1 BB potentials.
A numerical study of the two-meson Schrodinger equations in the (bqbar)(bqbar)
and (cqbar)(cqbar) sectors with the quark model potentials finds a single
"molecule", in the I=0 BB* sector. Binding in other channels might occur if the
quark model forces are augmented by pion exchange.Comment: 30 pages, 5 figures, revtex and epsfig. Submitted to Phys. Rev.
Sorting growing-finishing pigs by weight fails to improve growth performance or weight variation
A trial was conducted to determine the effects of sorting pigs by body weight at
placement on growth performance and weight variation at finishing. Unsorted pigs and heavy sorted pigs had higher ADG than medium or light sorted pigs. By the end of the trial, final body weights ranked in the
following descending order: heavy sorted,
unsorted, medium sorted, and light sorted.
Final weights of unsorted pigs were heavier
than the average final weight of all sorted
pigs. Additionally, differences in body
weight variation were not detectable by the
end of the study. These data suggest that
sorting pigs uniformly by weight to pens has
little effect on final variability in individual body weights and placing pigs into pens regardless of weight may increase the amount of pork produced from a system and
reduce turnaround time in barns
Benthic-pelagic trophic coupling in an Arctic marine food web along vertical water mass and organic matter gradients
Source at: http://doi.org/10.3354/meps12582Understanding drivers of benthic-pelagic coupling in Arctic marine ecosystems is key to identifying benthic areas that may be sensitive to climate-driven changes in hydrography and surface production. We coupled algal biomass and sedimentary characteristics with stable isotope data for 113 fishes and invertebrates in the Canadian Beaufort Sea and Amundsen Gulf to examine how trophic structure was influenced by the vertical water mass structure and organic matter input regimes, from 20 to 1000 m depths. Indices of community-level trophic diversity (isotopic niche size, 13C enrichment relative to a pelagic baseline, and δ13C isotopic range) increased from west to east, coincident with the use of more diverse dietary carbon sources among benthic functional groups. Data suggested benthic-pelagic trophic coupling was strongest in the western study region where pelagic sinking flux is relatively high, intermediate in the central region dominated by riverine inputs of terrestrial organic matter, and weakest in the east where strong pelagic grazing is known to limit sinking flux. Differences in δ13C between pelagic and benthic functional groups (up to 5.7 ‰) increased from west to east, and from the nearshore shelf to the upper slope. On the upper slope, much of the sinking organic matter may be intercepted in the water column, and dynamic hydrography likely diversifies available food sources. In waters > 750 m, there were no clear trends in benthic-pelagic coupling or community-level trophic diversity. This study represents the first description of fish and invertebrate food web structure > 200 m in the Canadian Beaufort Sea
Inefficient Vaginal Transmission of Tenofovir-Resistant HIV-1
Transmission of drug-resistant HIV has been postulated to be a threat to current first-line antiretroviral therapy (ART) regimens and the efficacy of several antiretroviral-based preexposure prophylaxis (PrEP) strategies being tested. Here we evaluated the effect of the common tenofovir (TFV) resistance mutation K65R on vaginal HIV transmission. Our results demonstrate that despite no overt loss of overall replication competence in vivo, this mutation results in significantly reduced mucosal transmission. When transmitted, the mutant virus eventually reverted to the wild type in 2 of 3 animals examined
The 2005 Nevada Rangeland Vegetation Survey General Public Questionnaire and Survey of Responses
The 2005 Nevada Rangeland Vegetation Survey was conducted as a collaborative effort between the University of Nevada, Reno (UNR) Department of Resource Economics and the University of Nevada Cooperative Extension (UNCE) Natural Resources Program to fulfill two roles
Consistency of Efficacy Results Across Various Clinical Measures and Statistical Methods in the Lecanemab Phase 2 Trial of Early Alzheimer’s Disease
BACKGROUND: Lecanemab (BAN2401) is a humanized IgG1 monoclonal antibody that preferentially targets soluble aggregated Aβ species (protofibrils) with activity at insoluble fibrils and slowed clinical decline in an 18-month phase 2 proof-of-concept study (Study 201; ClinicalTrials.gov NCT01767311) in 856 subjects with early Alzheimer\u27s disease (AD). In this trial, subjects were randomized to five lecanemab dose regimens or placebo. The primary efficacy endpoint was change from baseline in the Alzheimer\u27s Disease Composite Score (ADCOMS) at 12 months with Bayesian analyses. The key secondary endpoints were ADCOMS at 18 months and Clinical Dementia Rating-Sum-of-Boxes (CDR-SB) and Alzheimer\u27s Disease Assessment Scale-Cognitive Subscale (ADAS-Cog14) at 18 months. The results have been published previously. Herein, we describe the results of sensitivity analyses evaluating the consistency of the lecanemab efficacy results in Study 201 at the identified dose, the ED90, across multiple statistical methods and multiple endpoints over the duration of the study.
METHODS: The protocol-specified analysis model was a mixed model for repeated measures (MMRM). Sensitivity analyses address the consistency of the conclusions using multiple statistical methods. These include a disease progression model (DPM), a natural cubic spline (NCS) model, a quadratic mixed model (QMM), and 2 MMRMs with additional covariates.
RESULTS: The sensitivity analyses showed positive lecanemab treatment effects for all endpoints and all statistical models considered. The protocol-specified ADCOMS analysis showed a 29.7% slower decline than placebo for ADCOMS at 18 months. The various other analyses of 3 key endpoints showed declines ranging from 26.5 to 55.9%. The results at 12 months are also consistent with those at 18 months.
CONCLUSIONS: The conclusion of the primary analysis of the lecanemab Study 201 is strengthened by the consistently positive conclusions across multiple statistical models, across efficacy endpoints, and over time, despite missing data. The 18-month data from this trial was utilized in the design of the confirmatory phase 3 trial (Clarity AD) and allowed for proper powering for multiple, robust outcomes
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