Drinking water study raises health concerns for New Zealanders

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Quantifying the nitrate levels in bottled water in New Zealand

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Corrected Figure 3 for: Oliver, J., et al. (2018). "Group A Streptococcus pharyngitis and pharyngeal carriage: A meta-analysis." PLoS Neglected Tropical Diseases 12(3): e0006335. <div><br></div><div>Note that the legend for Fig. 3B has been corrected from the version presented in the manuscript to state "Serologically confirmed GAS pharyngitis".<br><br> .<div><div></div></div></div

Additional file 3: of Food safety labelling of chicken to prevent campylobacteriosis: consumer expectations and current practices

Chicken label analysis criteria. (DOCX 19 kb

Additional file 1: of Food safety labelling of chicken to prevent campylobacteriosis: consumer expectations and current practices

Chicken mock-up labels presented to consumers. (A) Current standard chicken label. (B) Current standard chicken label with information displayed in a larger font size. (C) Brightly-coloured warning label with large bold font, separate from the price and/or weight label. Consumers were asked to state which mock-up label was most effective at presenting information on safe chicken preparation to them. Note that information content was standardised across all three mock-up labels in order to isolate display differences. (EPS 1367 kb

Additional file 2: of Food safety labelling of chicken to prevent campylobacteriosis: consumer expectations and current practices

Survey form. (DOCX 85 kb

Additional file 3: of Food safety labelling of chicken to prevent campylobacteriosis: consumer expectations and current practices

Chicken label analysis criteria. (DOCX 19 kb

Proposed model of taxane sensitization mediated by miR-337-3p and its targets RAP1A and STAT3.

<p>Proposed model of taxane sensitization mediated by miR-337-3p and its targets RAP1A and STAT3.</p

siRNA knockdown of regulatory targets of miR-337-3p sensitizes NCI-H1155 cells to paclitaxel.

<p>(A) Effect of knockdown of <i>RAP1A</i> and <i>STAT3</i> expression by siRNA on cell viability in the presence and absence of paclitaxel. Shown in red is cell viability in 16 nM paclitaxel normalized to viability in carrier as a function of increasing concentrations of siRNAs against <i>RAP1A</i> or <i>STAT3</i>. Shown in black is cell viability in the absence of paclitaxel. (B) Effect of combined knockdown of <i>RAP1A</i> and <i>STAT3</i> on paclitaxel sensitivity. Shown is the relative cell viability in the presence 16 nM paclitaxel normalized to control oligos. (C) Knockdown of STAT3 and RAP1A enhances paclitaxel-induced G₂/M arrest as measured by flow cytometry. The ratio (R) of the G₂ to G₁ fractions induced by paclitaxel treatment was determined as above. (D) Cell viability as a function of oligo concentration (miR-337-3p mimic or negative control mimic) in the presence of cucurbitacin. *, p<0.05.</p

STAT3 and pSTAT3 levels correlate with resistance to taxanes in a panel of NSCLC cell lines.

<p>STAT3 and pSTAT3 protein levels were measured by RPPA. IC₅₀s were measured by MTS assay. Protein levels plotted against IC₅₀s for (A) paclitaxel and (B) docetaxel in 25 NSCLC cell lines. Correlations assumed that data were sampled from Gaussian populations (Pearson), and significance was assessed by one-tailed test.</p