Antitumor Activity of Selected Derivatives of Pyrazole- Benzenesulfonamides from Dilithiated C(α), N-Phenylhydrazones and Lithiated Methyl 2-(Aminosulfonyl)benzoate

Several pyrazole-benzenesulfonamides were subjected to biological evaluation involving tumor formation on potato discs caused by Agrobacterium tumefaciens. This assay led to some excellent and promising initial results with three of the pyrazole compounds showing increased tumor inhibition when compared to a recognized standard, camptothecin. The select pyrazole-benzenesulfonamides were prepared by condensation-cyclization of several dilithiated C(α),N-phenylhydrazones with lithiated methyl 2-aminosulfonyl-benzoate

CCDC 689210: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.,Related Article: C.R.Metz, J.D.Knight, S.J.Pastine, W.T.Pennington, C.F.Beam|2010|J.Chem.Cryst.|40|536|doi:10.1007/s10870-010-9692-

CCDC 657942: Experimental Crystal Structure Determination

Related Article: J.D.Knight, C.R.Metz, C.F.Beam, W.T.Pennington, D.G.VanDerveer|2008|Synth.Commun.|38|2465|doi:10.1080/00397910802138488,An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures

CCDC 1017987: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.,Related Article: S. Patrick Dunn, Matthew J. Walters, Clyde R. Metz, Charles F. Beam, William T. Pennington and Mariusz Krawiec|2004|J.Heterocycl.Chem.|41|1005|doi:10.1002/jhet.557041062

CCDC 695551: Experimental Crystal Structure Determination

Related Article: C.Potter, A.M.R.Smith, C.R.Metz, W.T.Pennington, D.G.VanDerveer, C.F.Beam|2010|J.Chem.Cryst.|40|541|doi:10.1007/s10870-010-9693-y,An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures

CCDC 695552: Experimental Crystal Structure Determination

Related Article: C.Potter, A.M.R.Smith, C.R.Metz, W.T.Pennington, D.G.VanDerveer, C.F.Beam|2010|J.Chem.Cryst.|40|541|doi:10.1007/s10870-010-9693-y,An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures

CCDC 955135: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.,Related Article: Clyde R. Metz, Jennifer L. Radke, William G. Shuler, Marco Gattoni Celli, Colin D. McMillen, William T. Pennington, Charles F. Beam|2014|J.Chem.Cryst.|44|401|doi:10.1007/s10870-014-0529-

CCDC 689212: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.,Related Article: C.R.Metz, J.D.Knight, A.C.Dawsey, W.T.Pennington, D.G.VanDerveer, J.B.Brown, K.J.Bigham, C.F.Beam|2010|J.Chem.Cryst.|40|296|doi:10.1007/s10870-009-9649-

CCDC 689211: Experimental Crystal Structure Determination

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.,Related Article: C.R.Metz, J.D.Knight, A.C.Dawsey, W.T.Pennington, D.G.VanDerveer, J.B.Brown, K.J.Bigham, C.F.Beam|2010|J.Chem.Cryst.|40|296|doi:10.1007/s10870-009-9649-