Instructional planning and new technologies in teacher education: the initial phase of a research project

The purpose of this work is to present the initial phase of a research project focused on the integration of technologies in the education of kindergarten and primary school student teachers through instructional planning. Firstly, we illustrate a tool designed for planning integrated learning units and describe the training path in which it was used. Secondly, we report the results of a preliminary study conducted with 96 students attending a university course that investigates two personal traits considered as prerequisites for using the tool: perceived proficiency in technology use, and opinions on the importance of each constituent element of the tool. With regard to both traits, some statistically significant variations emerged. The results obtained are an encouragement to continue the research project to verify whether the tool could be suitable to help student teachers develop an integrated planning procedure

MICROVASCULAR CHARACTERISTICS OF THE HUMAN FILIFORM PAPILLAE:A VIDEOCAPILLAROSCOPIC STDY.

The aim of this study was to observe the microcirculation characteristics of the human filiform papillae in healthy patients in vivo. Twenty healthy patients were examined using lingual capillaroscopy to investigate the characteristics of microcirculation of the human filiform papillae. Visibility, course, tortuosity, as well as the possible presence of microhemorrhages, the average caliber of the capillary loops and the number of visible capillary loops per square millimeter were evaluated for each patient. The investigation was simple, non-invasive and repeatable for each patient. Microcirculation architecture was characterized by a network of capillaries in polygonal mesh with parallel orientation in regard to the surface. Rare microhemorrhages were observed. The caliber of visible capillary loops was 12.5071.46 mm (mean7SD). The number of visible capillaries was 9.8871.06 (mean7SD). Our study shows that capillaroscopy of lingual filiform papillae is a practicable method. Future studies might evaluate whether microcirculation in that area is compromised or not during systemic pathologies involving peripheral microcirculation alterations. This method could also be applied to the study of microcirculation in pathologies which strictly pertain to the dental stomatological field

STUDY OF MICROCIRCULATION IN ORAL LICHEN PLANUS BY VIDEOCAPILLAROSCOPY

Objective. The aim of this study was to evaluate “in vivo” the oral microcirculatory characteristics in patients with oral lichen planus (OLP) and to discover any differences in microcirculation in comparison with healthy patients. Study design. Twenty patients with established diagnosis of OLP and 20 healthy patients were examined in our laboratory by means of contact optical probe videocapillaroscopy. The examined areas for each patient were the right and the left buccal mucosae. Capillary density and total capillary diameter, as well as afferent and efferent loop diameter were studied; the discovery of characteristic (tortuous, branched) loops was also investigated. Results. The results were observed by 2 different researchers using the capillaroscope’s software. Capillary density and the diameter of the afferent and efferent ansa were found to be significantly increased in OLP patients compared with controls. There was also a significant difference between the study of capillary tortuousity and the discovery of characteristic branched loops, indicating angiogenesis. Conclusions. Our methodology allowed an in vivo observation of the angiogenesis. Angiogenesis was interpreted as an increase in capillary density, total vascular caliber, and afferent and efferent loop caliber; the discovery of tortuous, branched loops, indicating the angiogenic phenomenon in vivo, was particularly significant. The capillaroscopy in correspondence with the lesion can be a very important method in the evaluation of the microcirculation of the patients suffering from OLP

A randomized trial assessing the effectiveness of different concentrations of isotretinoin in the management of lichen planus

The aim of our 10-year study was to test the effectiveness of topical therapy based on 0. 18% isotretinoin, comparing it with that most frequently used, i.e. at 0.05% concentration. Seventy patients with an established diagnosis of oral lichen planus were involved in the study. The patients were randomly divided into two groups, and the drug was administered topically at 0.05% and 0. 18% concentrations. The drug at the higher concentration, according to the same protocol, was administered to the patients who did not benefit from the therapy at the lower concentration. None of the cases of reticular lichen planus showed clinical or histological improvement. In contrast, the atrophic-erosive forms showed a significant improvement, both clinical and histological: in 26 patients (at 0.18% concentration) and in nine patients (at 0.05% concentration), the symptoms, as well as the erosions or ulcers observed, disappeared. The disappearance of dysplasic phenomena was observed at 0. 18% concentration. Topical application of the drug was accompanied by an increase in soreness and pain, as well as greater sensitivity to hot foods. However, these side effects were transitory, and considered acceptable by the patients. The proposed therapeutic protocol was effective towards highly active atrophic-erosive oral lichen planus with dysplasic phenomena, which is the form of the disease at higher risk of malignant evolution

Periodontal Alteration of the Microcirculation and Hypercholesterolemia: A Possible Correlation?

OBJECTIVE: We evaluated the morphological and parametric characteristics of the periodontal microcirculation in patients diagnosed as having hypercholesterolemia and high levels of low-density lipoprotein (LDL). METHODS: Forty patients were recruited, 20 of whom were affected by hypercholesterolemia and 20 of whom were considered healthy. A videocapillaroscopic examination was carried out on the periodontal mucosa in the proximity of the frenulum (II, V sextant). RESULTS: The difference between the parameters of the hypercholesterolemia group and the control group was evaluated with the Mann-Whitney U-test for non-parametric ordinal data; the level of significance being P < 0.05. The videocapillaroscopy documented extremely significant differences between the two groups, regarding the following parameters: total diameter of the loop (P = 0.0017), diameter of the afferent loops (P = 0.0004), diameter of the efferent loops (P = 0.00008) and periodontal density (P = 0.0001). CONCLUSIONS: The capillaroscopic examination revealed a morphological alteration of the periodontal microcirculation in patients with hypercholesterolemia, which is an expression of peripheral vascular phlogosis

Italian survey on benign paroxysmal positional vertigo

Benign paroxysmal positional vertigo (BPPV) is the most common type of peripheral vertigo. BPPV often relapses after the first episode, with a recurrence rate between 15% and 50%. To date both the aetiopathogenetic processes that lead to otoconia detachment and the factors that make BPPV a relapsing disease are still unclear, but recent epidemiological studies have shown a possible association with cardiovascular risk factors. The aim of the present study (Sesto Senso Survey) was to evaluate in the Italian population through an observational survey, the main demographic and clinical characteristics of patients with BPPV (first episode or recurrent) with particular focus on the potential cardiovascular risk factors. The survey was conducted in 158 vestibology centres across Italy on 2,682 patients (mean age 59.3 ± 15.0 years; 39.1% males and 60.9% females) suffering from BPPV, from January 2013 to December 2014. The results showed a high prevalence of cardiovascular risk factors such as high blood pressure (55.8%), hypercholesterolaemia (38.6%) and diabetes (17.7%), as well as a family history of cardiovascular disease (49.4%). A high percentage of patients also had hearing loss (42.9%), tinnitus (41.2%), or both (26.8%). The presence of hypertension, dyslipidaemia and pre-existing cardiovascular comorbidities were significantly related to recurrent BPPV episodes (OR range between 1.84 and 2.31). In addition, the association with diabetes and thyroid/autoimmune disease (OR range between 1.73 and 1.89) was relevant. The survey results confirm the significant association between cardiovascular comorbidities and recurrent BPPV and identify them as a potential important risk factor for recurrence of BPPV in the Italian population, paving the way for the evaluation of new therapeutic strategies in the treatment of this disease

placement optimization of biodiesel production plant by means of centroid mathematical method

Abstract The uncertainty about the world energy production, the lack of crude oil reserves, the environmental problems caused by a massive use of fossil fuels and their increased prices, are the main reasons inducing modern society to find alternative solutions for fuels production. According to this point of view, a great attention is addressed to the biodiesel production as substitute of diesel derived by fossil hydrocarbons. The use of biomasses from different sources for the energy production constitutes one of the main objects thanks to which European Community intends to reduce its dependence from oil importations and derived products over the medium to longer term. Several sources can be used for biodiesel production, among these Brassica carinata and Brassica napus are considered as possible dedicated energy crops. The present work is based on the implementation of a model that allows to analyze the insertion of agro-energetic farms, identifying and evaluating the crops previously mentioned, economically suitable to enter in rotation with cereals and legumes. Through the analysis of official statistical data and cereals and legumes production, an estimation of potential biodiesel production in relation with the considered territory chosen as case study. It was implemented a model based on a procedure of logistics and distribution management in Matlab and in a Gis environment in order to find the best location for a potential production plant. The model considered some collection points of crops according the administrative units of the territory of reference. Moreover, for the same territory, thanks to some simulations it was calculated how the potential biodiesel production could affect fuels consumption and the potential reduction of the amount of CO2 in the environment

Laser-generated plasmas by graphene nanoplatelets embedded into polyethylene

AbstractGraphene micrometric particles have been embedded into polyethylene at different concentrations by using chemical–physical processes. The synthesized material was characterized in terms of mechanical and optical properties, and Raman spectroscopy. Obtained targets were irradiated by using a Nd:YAG laser at intensities of the order of 1010 W/cm2 to generate non-equilibrium plasma expanding in vacuum. The laser–matter interaction produces charge separation effects with consequent acceleration of protons and carbon ions. Plasma was characterized using time-of-flight measurements of the accelerated ions. Applications of the produced targets in order to generate carbon and proton ion beams from laser-generated plasma are presented and discussed

Integration of HVSR measures and stratigraphic constraints for seismic microzonation studies: the case of Oliveri (ME)

Because of its high seismic hazard the urban area of Oliveri has been subject of first level seismic microzonation. The town develops on a large coastal plain made of mixed fluvial/marine sediments, overlapping a complexly deformed substrate. In order to identify points on the area probably suffering relevant site effects and define a preliminary Vs subsurface model for the first level of microzonation, we performed 23 HVSR measurements. A clustering technique of continuous signals has been used to optimize the calculation of the HVSR curves. 42 reliable peaks of the H/V spectra in the frequency range 0.6–10 Hz have been identified. A second clustering technique has been applied to the set of 42 vectors, containing Cartesian coordinates, central frequency and amplitude of each peak to identify subsets which can be attributed to continuous spatial phenomena. The algorithm has identified three main clusters that cover significant parts of the territory of Oliveri. The HVSR data inversion has been constrained by stratigraphic data of a borehole. To map the trend of the roof of the seismic bedrock, from the complete set of model parameters only the depth of the seismic interface that generates peaks fitting those belonging to two clusters characterized by lower frequency has been extracted

Factors influencing the development of otitis media among Sicilian children affected by upper respiratory tract infections

Introduction: Upper respiratory tract infection is a nonspecific term used to describe an acute infection involving the nose, paranasal sinuses, pharynx and larynx. Upper respiratory tract infections in children are often associated with Eustachian tube dysfunction and complicated by otitis media, an inflammatory process within the middle ear. Environmental, epidemiologic and familial risk factors for otitis media (such as sex, socioeconomic and educational factors, smoke exposure, allergy or duration of breastfeeding) have been previously reported, but actually no data about their diffusion among Sicilian children with upper respiratory tract infections are available. Objective: To investigate the main risk factors for otitis media and their prevalence in Sicilian children with and without upper respiratory tract infections. Methods: A case-control study of 204 children with upper respiratory tract infections who developed otitis media during a 3 weeks monitoring period and 204 age and sex-matched healthy controls. Seventeen epidemiologically relevant features were inventoried by means of standardized questionnaires and skin tests were performed. Univariate analysis and multivariate logistic regression analysis were used to examine the association between risk factors and occurrence of otitis media. Results: Otitis media resulted strongly associated to large families, low parental educational attainment, schooling within the third years of life (p &lt;. 0.05); children were more susceptible to develop otitis media in the presence of asthma, cough, laryngopharyngeal reflux disease, snoring and apnea (p &lt;. 0.05). Allergy and urban localization increased the risk of otitis media in children exposed to smoke respectively of 166% and 277% (p &lt;. 0.05); the joint effect of asthma and presence of pets in allergic population increased the risk of recurrence of 11%, while allergy, cough and runny nose together increased this risk of 74%. Conclusions: Upper respiratory tract infections and otitis media are common childhood diseases strongly associated with low parental educational attainment (p = 0.0001), exposure to smoke (p = 0.0001), indoor exposure to mold (p = 0.0001), laryngopharyngeal reflux disease (p = 0.0002) and the lack of breast-feeding (p = 0.0014); an increased risk of otitis media recurrences was observed in the presence of allergy, persistent cough and runny nose (p = 0.0001). The modification of the identified risk factors for otitis media should be recommended to realize a correct primary care intervention