A Synchronous undifferentiated nasopharyngeal carcinoma and infiltrating ductal carcinoma of the breast successfully treated with induction chemotherapy followed by local control of both tumours: a case report

<p>Abstract</p> <p>Background</p> <p>Multiple primary cancers have a low incidence particularly when cancers are synchronous. Few cases of synchronous head and neck cancer and breast carcinoma are reported in the literature.</p> <p>Case presentation</p> <p>We report here an exceptional case of a 47 years old Moroccan woman presenting two synchronous cancers, the first in the nasopharynx and the second in the breast. The patient was treated successfully with a combined strategy associating chemotherapy, radiation therapy, and surgery. She remains disease free after 27 months of follow up.</p> <p>Conclusions</p> <p>Treatment strategy in the case of multiple primary cancers remains controversial because of the variety of presentations; initial aggressive treatment reports good results.</p

Triple malignancy in a single patient including a cervical carcinoma, a basal cell carcinoma of the skin and a neuroendocrine carcinoma from an unknown primary site: A case report and review of the literature

<p>Abstract</p> <p>Introduction</p> <p>The occurrence of multiple primary cancers is rare. Only a few cases and patient reviews of an association of triple malignancy have been reported.</p> <p>Case presentation</p> <p>We report here a case of a 78-year-old Moroccan woman presenting initially with a synchronous double malignancy, the first in her cervix and the second in her skin. Our patient was treated with radiation therapy for both tumors and remained in good control for 17 years, when she developed a metastatic disease from a neuroendocrine carcinoma of an unknown primary site.</p> <p>Conclusions</p> <p>Although the association of multiple primary cancers can be considered a rare occurrence, improving survival in cancer patients has made this situation more frequent.</p

Effect of the greenhouse design on the thermal behavior and microclimate distribution in greenhouses installed under semi-arid climate

International audienceGreenhouse design and cover material properties may strongly impact greenhouse energy. To study the effect of these parameters, three typical unheated agricultural buildings equipped with rows of canopy were considered, and two-dimensional simulations were conducted using the discrete ordinate model for simulating radiative transfers. Experiments were conducted to establish the boundary conditions and to validate the model. Two parametric studies were carried out: one for the nocturnal period when the energy performance of each type of greenhouse was investigated, and one for the diurnal period, when the sun path was simulated taking into account the type of the cover, its spectral optical and thermal properties. Results indicate that for the diurnal period, and for both plastic greenhouses equipped with fully opened side vents, the air located between the rows of canopy and ground surfaces remained very slow, not exceeding 0.2 m/s; for the Venlo glasshouse, the recirculation loop situated above the crop improved the air mixing and induced a good homogenization. Results also indicate that the cover material with the highest absorptivity, deteriorated the natural ventilation, increasing the air temperature by convection, enhancing local air temperature favoring the development of a secondary recirculation, and reduced the available photosynthetically active radiation. Concerning the nocturnal period, the ambient air temperature in the tunnel and in the vertical wall of the greenhouse was relatively homogenous and warmer than the temperature in the Venlo greenhouse. During the nocturnal period, the plastic greenhouse (in particular the one with the tunnel) performed better in regard to the homogenization of the climate and thermal energy storage

Numerical Simulation of the Airflow and Temperature Distribution in a Closed Empty Venlo Glasshouse under Hot and Arid Climate

International audienceThe thermal behavior of the inside air of a closed Venlo glasshouse without plants was analysed under semi-arid climate conditions. The aim of the study was to investigate to what extent the characteristics of the greenhouse design and outside climatic conditions influence airflow and temperature patterns inside the greenhouse. For the purpose of the present work, a CFD modeling approach was combined with field surveys. The study focuses on the effects of (i) the thermal inertia of the soil, (ii) the movement of the interior air, and (iii) the distribution of the temperature inside the greenhouse. Two contrasted days were considered: a windy overcast day and clear day. From the results, it is concluded that when the greenhouse is fully closed with bare soil, the heat absorbed and stored by the ground during daytime represents a significant heat source which enhances buoyancy forces, the main driving forces of the movement of the air, especially during the night. The temperature of the roof was relatively low and the air temperature distribution inside the greenhouse disclosed a vertical gradient from the roof towards the ground surface due to the movement of the air above the surface of the ground absorbing thermal energy (solar energy). Maximum air velocities inside the greenhouse were observed near the ground surface, while they reached their minimum values in the middle of the greenhouse. Similar results were obtained for the windy overcast day and for the clear day

Discrete Distortion for 3D Data Analysis

We investigate a morphological approach to the analysis and understanding of three-dimensional scalar fields, and we consider applications to 3D medical and molecular images as examples.We consider a discrete model of the scalar field obtained by discretizing its 3D domain into a tetrahedral mesh. In particular, our meshes correspond to approximations at uniform or variable resolution extracted from a multi-resolution model of the 3D scalar field, that we call a hierarchy of diamonds. We analyze the images based on the concept of discrete distortion, that we have introduced in [26], and on segmentations based on Morse theory. Discrete distortion is defined by considering the graph of the discrete 3D field, which is a tetrahedral hypersurface in R 4, and measuring the distortion of the transformation which maps the tetrahedral mesh discretizing the scalar field domain into the mesh representing its graph in R 4. We describe a segmentation algorithm to produce Morse decompositions of a 3D scalar field which uses a watershed approach and we apply it to 3D images by using as scalar field both intensity and discrete distortion. We present experimental results by considering the influence of resolution on distortion computation. In particular, we show that the salient features of the distortion field appear prominently in lower resolution approximations to the dataset

Brainhack: a collaborative workshop for the open neuroscience community

Brainhack events offer a novel workshop format with participant-generated content that caters to the rapidly growing open neuroscience community. Including components from hackathons and unconferences, as well as parallel educational sessions, Brainhack fosters novel collaborations around the interests of its attendees. Here we provide an overview of its structure, past events, and example projects. Additionally, we outline current innovations such as regional events and post-conference publications. Through introducing Brainhack to the wider neuroscience community, we hope to provide a unique conference format that promotes the features of collaborative, open science